ChronicObstructive Pulmonary Disease (COPD) is a primary cause of death in global, particularly in lowresource settings with insufficient medical facilities arising because of high costs of medical apparatus, diagnosis and treatment. The Long Term Oxygen Therapy (LTOT) is used to treat COPD patients as it has been shown to improve patient survival and better life expectancy; however, it is also an expensive treatment, making it difficult to use in poor-resource settings. This review discusses various LTOT devices and evaluates their suitable applicability in resource poor settings. The devices are compared based on their cost (both capital and operational) and performance. The article also discusses the observation of oxygen supply during treatment and the use of delivery systems.