Design and development of portable potentiostat for advanced research in electrochemical biosensing

Bukkawar, Sarika; Sarwade, Nisha; Panse, M. S.; Muthurajan, H.

doi:10.1109/icpcsi.2017.8392173

Cited by 5 publications

(7 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The electrode developed in this study showed comparable performance to that of other electrodes previously developed in different studies. A few research studies, such as those in [ 40 , 45 ], developed electrodes that had linear ranges outside the permissible levels in the water. Furthermore, the electrodes were developed using complicated and multiple preparation and modification steps, such as ball milling [ 47 ], reflux heating for the preparation of zinc-based metal-organic frameworks [ 41 ], and the implementation of numerous materials for detection, such as hemoglobin, Nafion, palladium, and graphene in Ref.…”

Section: Investigation Resultsmentioning

confidence: 99%

Towards Embedded Electrochemical Sensors for On-Site Nitrite Detection by Gold Nanoparticles Modified Screen Printed Carbon Electrodes

Adiraju

Munjal

Viehweger

et al. 2023

Sensors

View full text Add to dashboard Cite

The transition of electrochemical sensors from lab-based measurements to real-time analysis requires special attention to different aspects in addition to the classical development of new sensing materials. Several critical challenges need to be addressed including a reproducible fabrication procedure, stability, lifetime, and development of cost-effective sensor electronics. In this paper, we address these aspects exemplarily for a nitrite sensor. An electrochemical sensor has been developed using one-step electrodeposited (Ed) gold nanoparticles (EdAu) for the detection of nitrite in water, which shows a low limit of detection of 0.38 µM and excellent analytical capabilities in groundwater. Experimental investigations with 10 realized sensors show a very high reproducibility enabling mass production. A comprehensive investigation of the sensor drift by calendar and cyclic aging was carried out for 160 cycles to assess the stability of the electrodes. Electrochemical impedance spectroscopy (EIS) shows significant changes with increasing aging inferring the deterioration of the electrode surface. To enable on-site measurements outside the laboratory, a compact and cost-effective wireless potentiostat combining cyclic and square wave voltammetry, and EIS capabilities has been designed and validated. The implemented methodology in this study builds a basis for the development of further on-site distributed electrochemical sensor networks.

show abstract

Section: Investigation Resultsmentioning

confidence: 99%

Towards Embedded Electrochemical Sensors for On-Site Nitrite Detection by Gold Nanoparticles Modified Screen Printed Carbon Electrodes

Adiraju

Munjal

Viehweger

et al. 2023

Sensors

View full text Add to dashboard Cite

show abstract

“…Our prototype has also carried out tests for 6 different measurement methods. [3] Unreported USB C8051F005 CV 1 [4] 50 Bluetooth, Wifi ESP 32, Arduino Uno CV, LSV, CA 1 [5] Unreported USB ATxmega32E5 CV, LSV, SWV, ASV, CA 1 [7] Unreported USB ATmega328 LSV 1 [8] 40 USB Arduino Uno CV, LSV, CA 1 [9] 55 USB Arduino Teensy 3.2 CV, LSV, CA, CC 1 [10] Unreported USB STM32F103RCT6 Unreported 1 [19] While in the CA, the graph pattern was appropriate, indicating the same measurement characteristics as the Emstat Pico potentiostat with its module only integrated with the USB module. We can also see that, in general, potentiostats have one measurement channel, while in this study, we show that three measurement channels can be run semi-parallelly.…”

Section: Electrochemical Measurements and Performance Comparisonmentioning

confidence: 99%

“…Ministat, according to research by Adams et al, uses the R environment for the graphical user interface (GUI) [5], while Pansodtee uses Python [6]. In contrast, Bukkawar et al prefer to use Microsoft Excel as the GUI [7]. In addition, instruments to support chemistry learning have been developed specifically for electrochemistry using a similar approach.…”

Section: Introductionmentioning

confidence: 99%

“…The implementation was carried out to manufacture electrochemical instruments with potentiostats based on several microcontrollers. Several studies that implement microcontroller-based potentiostats, including those conducted by Melenbrink et al using Arduino [8], Glasscott et al using Teensy [9], Adams et al using ATxmega32E5 [7], and Ning et al using STM32 as their potentiostat microcontroller [10].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

ESPotensio: A Low-Cost and Portable Potentiostat With Multi-Channel and Multi-Analysis Electrochemical Measurements

et al. 2022

View full text Add to dashboard Cite

Electrochemical method is often chosen to analyze various bio-chemical reactions due to its operation simplicity with versatile applications. Thus, for this purpose, the procurement of potentiostat, an electrochemical-based analysis instrument, also needs to focus on the low price, but maintaining its rich analysis features. In this paper, we designed a low-cost and portable potentiostat system based on the ESP32 microcontroller. Even with the low-cost system design, it supports various electrochemical measurement methods, i.e. cyclic voltammetry (CV), linear sweep voltammetry (LSV), square wave voltammetry (SWV), differential pulse voltammetry (DPV), normal pulse voltammetry (NPV), and the observation of electrochemical current against time based on chronoamperometry measurement method. The potentiostat performance was assessed by the electrochemical signal accuracy and errors. Furthermore, the measurements can also be carried out semi-parallelly within three measurement channels simultaneously. The results showed that it could produce voltammograms with an average accuracy of more than 90%, compared to the commercial Emstat Pico. Even though having this comprehensive and extensive electrochemical analysis, the cost of the total system realization could be downsized to only USD 21.4.

show abstract

“…The electrochemical equipment is also considerably smaller and more portable. For instance, a hand-held potentiostat that has been commercially available for years . However, more importantly, potential scanning can be modulated using the equipment, such that the measurements can “trace” or “resonate with” the molecular motion of the analyte molecules .…”

mentioning

confidence: 99%

Electrochemical Resonance of Molecular Motion Enabling Label-, Antibody-, and Enzyme-Free Detection of SARS-CoV-2

Zhou

Hao

et al. 2021

ACS Sens.

View full text Add to dashboard Cite

In this work, we developed a method to detect two viral marker proteins, the main protease and the spike protein (S protein), of SARS-CoV-2, as well as a host marker, chemokine receptor 5 (CCR5), which is associated with the risk of developing the severe acute respiratory syndrome. This assay can be completed in two steps in a label-free fashion, yielding a “signal-on” signal readout, which usually cannot be attained by electrochemical label-free detection using no labels or markers to tag the target protein. The proposed assay also utilizes no antibodies or enzyme-based reagents. The method achieves this performance by moderating the frequency of electrochemical potential scanning such that the scanning rate keeps pace with, or “resonances” with, the molecular motion of the probe molecule. This method has been successfully applied to detect the three target proteins in serum samples collected from patients infected with SARS-CoV-2, and the results indicate a strong correlation with the risk of deteriorating into severe acute conditions after virus infection. Soon, the clinical application of this method may provide a low-cost but effective method for virus surveillance in the general public.

show abstract

Design and development of portable potentiostat for advanced research in electrochemical biosensing

Cited by 5 publications

References 14 publications

Towards Embedded Electrochemical Sensors for On-Site Nitrite Detection by Gold Nanoparticles Modified Screen Printed Carbon Electrodes

Towards Embedded Electrochemical Sensors for On-Site Nitrite Detection by Gold Nanoparticles Modified Screen Printed Carbon Electrodes

ESPotensio: A Low-Cost and Portable Potentiostat With Multi-Channel and Multi-Analysis Electrochemical Measurements

Electrochemical Resonance of Molecular Motion Enabling Label-, Antibody-, and Enzyme-Free Detection of SARS-CoV-2

Contact Info

Product

Resources

About