Design and Development of Peel-off Mask Gel Formulation of Citronella Oil for Acne Vulgaris

Rahmasari, Dyah; Ermawati, Dian Eka; Nugraheni, Raditya Weka; Putri, Dwi Ramadhaningtyas; Pratiwi, Indah Nur

doi:10.5220/0009126101570163

Cited by 4 publications

(7 citation statements)

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“…When the gel covers the skin's surface with a thick film, spreading the gel becomes hard for volunteers. However, the formula still has much water in it, which can make it take longer for the peel‐off mask to dry and create a solid layer, similar to other studies 45,46 …”

Section: Resultssupporting

confidence: 73%

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Formulation and evaluation of antioxidant and antibacterial activity of a peel‐off facial masks moisturizer containing curcumin and Rosa Damascena extract

Nemati,

Abedi,

Ghasemi

et al. 2024

J of Cosmetic Dermatology

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BackgroundAcne is a common skin issue that typically occurs during adolescence. It causes long‐lasting redness and swelling in the skin. An alternative approach to treating acne could involve using a cosmetic facial mask containing herbal ingredients such as Curcumin and Rosa Damascena extract for its antibacterial properties.AimsThis study aims to create and try out a peel‐off mask gel made from Curcumin and R. Damascena extract. This gel is intended to have the ability to kill bacteria such as Staphylococcus aureus, Escherichia coli, and Propionibacterium acnes and remove dead cells from the skin surface.MethodsThe peel‐off mask was made using polyvinyl alcohol (PVA) in 8% and 10% as solidifier. The evaluation of peel‐off masks comprises the examination of physiochemical and mechanical aspects. Furthermore, their longevity, effectiveness, and antibacterial properties are also considered.ResultsThe white color, pleasant smell, and soft texture were the defining features of the peel‐off gel mask. The changes in PVA affect the pH level, thickness, and how quickly the peel‐off mask dries. The stability test found that the peel‐off mask had no significant physical changes when exposed to freezing and thawing. However, there were some differences in color and separation when using the real‐time method. A prepared peel‐off mask containing 10% PVA and curcumin works best against P. acne. The amount of PVA in the formula affected the physical and chemical qualities, but it did not impact on the antibacterial abilities of the peel‐off mask gel. The best formula that gives the best results uses 10% PVA + curcumin.ConclusionsUsing the Curcumin and R. Damascena extract in the creation of the peel‐off mask gel ensures its efficacy and safety for skin application.

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Section: Resultssupporting

confidence: 73%

“…However, the formula still has much water in it, which can make it take longer for the peel-off mask to dry and create a solid layer, similar to other studies. 45,46 3.…”

Section: Spreadability Testmentioning

confidence: 99%

Formulation and evaluation of antioxidant and antibacterial activity of a peel‐off facial masks moisturizer containing curcumin and Rosa Damascena extract

Nemati,

Abedi,

Ghasemi

et al. 2024

J of Cosmetic Dermatology

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“…All formulations had appropriate pH in the range of 4 to 7, which is safe for use on the skin. In general, PVA is a water-soluble polymer which has a pH value of 5-8 (Rahmasari et al, 2019). An increase in the concentration of PVA from 7.5 %w/w to 20.0 %w/w resulted in the lower pH of formulations (6.24 vs 5.14) (Table I).…”

Section: Physical Characterization Of the Peel-off Mask Filmmentioning

confidence: 99%

Clindamycin peel-off mask film, an effective formulation for C. acnes treatment: characterization and microbiological activity

Morakul

Wongrakpanich²,

Teeranachaideekul³

et al. 2023

Indonesian J Pharm

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Clindamycin is the antibiotic of choice for treating Cutibacterium acnes (C. acnes) which was presented in various dosage forms such as topical solution, gel, and foam. In this current study, clindamycin was formulated as the peel-off mask gel, intending to form film, providing the drug release profile in a sustained manner leading to better antimicrobial efficacy and enabling peel-off after use. The peel-off mask gel was designed into many formulations with varying concentrations of film-forming agents. The major film-forming agent was 10 %w/w PVA that was combined with the additional film-forming agents PVP-K30 or SA. Clindamycin 1 %w/w was loaded in the selected formulations F18 (10 %w/w PVA and 20 %w/w PVP-K30) and F21 (10 %w/w PVA and 1.5 %w/w SA). The physical property evaluation of the peel-off mask gel showed that the types and concentrations of film-forming agents influenced the viscosity, spreadability, and film-forming ability. The film’s tensile strength indicating the preference of use was also determined. There was no interaction between the ingredients in the formulation evaluated by FT-IR, XRD, and DSC. The F18 and F21 formulations showed a good to very good spreadability and film-forming ability, a suitable tensile strength with a drying time of approximately 8 min, and pH 4-5. Both formulations provided the highest antimicrobial susceptibility for C. acnes compared to the blank film and the clindamycin solution indicating the potential to be developed as the new market formulation for acne treatment.

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“…The peel was allowed to dry. According to the studies, the ideal drying time of the peel able mask gel is 15-30 minutes [44]. The drying time of the gel mask was then determined using a stopwatch.…”

Section: ) Color and Odourmentioning

confidence: 99%

“…PVA is a lm-forming or gelling agent and has considerable exibility. This will cause a greater binding and retention of the uid by the gelling agent, so the viscosity of the mask increases [44]. The viscosity value of the peel off gel mask was determined 111.57 cSt.…”

Section: Determination Of Viscositymentioning

confidence: 99%

Formulation and evaluation of peel-off gel mask with St. John's Wort oil and activated carbon from pinecone

Yağmur

Kaya

Özer

2023

Preprint

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Objective Skin needs care to protect against environmental pollution. The facial skin can be protected such as cream, peel off mask and lotion facemask. This study aim is to develop the antibacterial peel-off mask gel containing St. John's Wort Oil (Hypericum perforatum oil).Methods This peel-off gel mask consists of ascorbic acid, polyvinyl alcohol (PVA, as preservative), polyethylene glycol (peg), glycrine (as plasticizer), polysorbate (tween twenty, as stabilizer), ethanol and distilled water with the addition of St. John's Wort Oil and active carbon. The peel-off physical properties (homogeneity, spreadability, viscosity, film-drying time), chemical properties (pH value, stability and antibacterial activity properties) were examined. Using of an active ingredient in peel off mask, it strengthens the role of peel off mask by opening the clogged pores. Activated carbon was added to this formulation as an active ingredient due to its adsorbent activity. In this present study, activated carbon was obtained from pinecone.Results The specific surface area (SBET) of activated carbon was found to be 536.998 m²/g. The antimicrobial activity of the St. John's Wort Oil was tested against Gram-negative bacteria (Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus) as well as one pathogenic fungus (Candida albicans, ATCC 10231). Disc diffusion method was used to study antimicrobial activity.Conclusion The prepared peel of mask showed a good peeling feature without causing edema or irritation on the skin and that it can increase skin cleansing by removing the dirt in the skin pores.

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Design and Development of Peel-off Mask Gel Formulation of Citronella Oil for Acne Vulgaris

Cited by 4 publications

References 0 publications

Formulation and evaluation of antioxidant and antibacterial activity of a peel‐off facial masks moisturizer containing curcumin and Rosa Damascena extract

Formulation and evaluation of antioxidant and antibacterial activity of a peel‐off facial masks moisturizer containing curcumin and Rosa Damascena extract

Clindamycin peel-off mask film, an effective formulation for C. acnes treatment: characterization and microbiological activity

Formulation and evaluation of peel-off gel mask with St. John's Wort oil and activated carbon from pinecone

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