<p>High-rise buildings are progressively being designed and constructed in increasingly slender and complex shapes. Consequently, excessive wind-induced vibrations of these structures are a growing serviceability concern due to their flexibility. Tuned mass dampers (TMDs) are regularly incorporated into high-rise buildings for mitigating excessive wind-induced vibrations. However, traditional TMDs are only effective over a narrow domain of frequencies, require an immense mass and occupy a significant volume of interior space. A novel modular air-tuned damper system was developed which is more cost-effective and flexible in distributing its mass throughout a building to make efficient use of unused space. Importantly, the air-tuned damper system is capable of being tuned across a broad domain of frequencies to more effectively alleviate wind-induced vibrations. This paper presents a case study demonstrating the performance of a high-rise building under 1- year and 10-year wind events whilst equipped with the air-tuned damper system. Dynamic analyses were performed for evaluating the reductions of the building’s lateral accelerations considering different air-tuned damper configurations. The performance of the building under the different damper configurations is discussed.</p>