Design and characterization of Cu(II) complexes from 2-benzoylpyridine benzhydrazone: Crystallographic evidence for coordination versatility

Mangalam, Neema Ani; Sivakumar, S.; Kurup, M.R. Prathapachandra; Suresh, Eringathodi

doi:10.1016/j.saa.2009.11.040

Cited by 42 publications

(10 citation statements)

References 33 publications

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“…The inversion related pairs of molecules are linked together via CuÁÁÁO interactions. The CuÁÁÁO3A distance is 2.690 Å which is slightly longer than the common range of Cu-O bond lengths (1.9-2.6 Å ) (A: 1 -x, 2 -y, 1 -z) [27][28][29]. The copper atoms are separated by a distance of 3.352 Å .…”

Section: Structures Of 2 Andmentioning

confidence: 99%

Synthesis, structural characterization and thermal properties of three copper(II) complexes based on aryl hydrazide ligands

Zhao

Dou

et al. 2011

Transition Met Chem

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The thiosemicarbazide and hydrazide Cu(II) complexes, [Cu 3 L 2 1 (py) 4 Cl 2 ] (1), [Cu(HL 2 )py] (2) and [Cu(HL 3 )py] (3), (H 2 L 1 = 1-picolinoylthiosemicarbazide, H 3 L 2 = N 0 -(2-hydroxybenzylidene)-3-hydroxy-2-naphthohydrazide, H 3 L 3 = 2-hydroxy-N 0 -((2-hydroxy-naphthalen-1-yl)methylene)benzohydrazide) have been prepared and characterized through physicochemical and spectroscopic methods as well as X-ray crystallography. Complex 1 has a centrosymmetric structure with -N-N-bridged Cu 3 skeleton. Neighboring molecules are linked into a 3D supermolecular framework by p-p stacking interactions, N-HÁÁÁCl and C-HÁÁÁCl hydrogen bonds. Complexes 2 and 3 have similar planar structures but different dimers formed by concomitant CuÁÁÁN and CuÁÁÁO interactions, respectively. Solvent accessible voids with a volume of 391 Å 3 are included in the structure of complex 2, indicating that this complex is a potential host candidate. Thermogravimetric analysis shows that the three complexes are stable up to 100°C.

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Section: Structures Of 2 Andmentioning

confidence: 99%

Synthesis, structural characterization and thermal properties of three copper(II) complexes based on aryl hydrazide ligands

Zhao

Dou

et al. 2011

Transition Met Chem

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“…The C8–O3 bond length is very close to the expected enolato bond length (1.318 Å). [ 35 ] The torsion angle value of 178.6(3) of the N(2)–N(1)–C(7)–C(6) moiety indicates an E configuration with respect to C7–N1 bond. Also, compound adopts a Z configuration with respect to N2–C8 bond that is clear from the torsion angle value of the moiety N(1)–N(2)–C(8)–O(3) (−1.4(4)).…”

Section: Resultsmentioning

confidence: 99%

“…Newly formed (C=N) bond stretching is observed in the range 1601–1608 cm −1 . [ 35 ] Bands in the range 1114–1149 cm −1 are due to ν(N–N) stretching. [ 41 ] The ν(C–O) stretching in all these complexes is observed in the range 1211–1267 cm −1 (Figures S3–S5).…”

Section: Resultsmentioning

confidence: 99%

Novel dioxidomolybdenum complexes containing ONO chelators: Synthesis, physicochemical properties, crystal structures, Hirshfeld surface analysis, DNA binding/cleavage studies, docking, and in vitro cytotoxicity

Vineetha

Joy

Krishna

et al. 2021

Applied Organom Chemis

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A series of dioxidomolybdenum (VI) complexes, [MoO2(ESB)H2O]·DMF (1), [MoO2(ESB)MeOH] (2), and [MoO2(ESB)H2O]·EtOH (3), containing 3‐ethoxysalicylaldehyde benzoylhydrazone have been synthesized and analysed using various spectral and analytical techniques such as elemental analyses, IR spectra, UV–Vis absorption spectra, X‐ray crystallography, and Hirshfeld surface analysis. Based on the elemental and spectral analysis, six‐coordinate geometry was assigned for these complexes wherein the hydrazone ligand binds to the metal centre in its dianionic enolate form through ONO donor set. Distorted octahedral geometry of complexes 1 and 2 was evidenced from their crystal structures, which is typical for many cis‐dioxido complexes of MoVI. The proligand and the new complexes were examined for their DNA binding, DNA cleavage, and cytotoxic properties. The DNA binding efficiency of the compounds in terms of their binding constants (Kb) of the metal complexes was observed to be 1.3727 × 105 M−1, 3.0194 × 104 M−1, and 1.13206 × 104 M−1 for [MoO2(ESB)H2O]·DMF (1), [MoO2(ESB)MeOH] (2), and [MoO2(ESB)H2O]·EtOH (3), respectively, indicating that these complexes strongly bind to DNA. To determine the binding interactions of the complexes with DNA and protein (BSA), molecular docking studies were carried out. Gel electrophoresis study reveals the fact that the complexes cleaved supercoiled pUC‐18 DNA to nicked form (Form II) in the presence and absence of H2O2. The complexes showed significantly high cytotoxicity against MCF‐7 (breast cancer cells).

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“…This paper is an extension of our earlier studies with transition metal complexes of acylhydrazones [11,12]. An attractive aspect of hydrazones is that they are capable of exhibiting keto-enol tautomerism and can coordinate in tridentate neutral NNO donor mode [13], monoanionic NNO donor mode [14], dianionic tridentate ONO form [15], tetraanionic form [16] and bidentate neutral NO forms [17] to the metal ions generating mononuclear, dinuclear or polynuclear species.…”

Section: Introductionmentioning

confidence: 84%

Mn(II) complexes of some acylhydrazones with NNO donor sites: Syntheses, a spectroscopic view on their coordination possibilities and crystal structures

2010

Self Cite

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Mn(II) complexes derived from a set of acylhydrazones were synthesised and characterized by elemental analyzes, IR, UV-vis and X-band EPR spectral studies as well as conductivity and magnetic susceptibility measurements. In the reported complexes, the hydrazones exist either in the keto or enolate form, as evidenced by IR spectral data. Crystal structures of two complexes are well established using single crystal X-ray diffraction studies. In both of these complexes two equivalent monoanionic ligands are coordinated in a meridional fashion using cis pyridyl, trans azomethine nitrogen and cis enolate oxygen atoms positioned very nearly perpendicular to each other. EPR spectra in DMF solutions at 77 K show hyperfine sextets and in some of the complexes the low intensity forbidden lines lying between each of the two hyperfine lines are also observed.

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Design and characterization of Cu(II) complexes from 2-benzoylpyridine benzhydrazone: Crystallographic evidence for coordination versatility

Cited by 42 publications

References 33 publications

Synthesis, structural characterization and thermal properties of three copper(II) complexes based on aryl hydrazide ligands

Synthesis, structural characterization and thermal properties of three copper(II) complexes based on aryl hydrazide ligands

Novel dioxidomolybdenum complexes containing ONO chelators: Synthesis, physicochemical properties, crystal structures, Hirshfeld surface analysis, DNA binding/cleavage studies, docking, and in vitro cytotoxicity

Mn(II) complexes of some acylhydrazones with NNO donor sites: Syntheses, a spectroscopic view on their coordination possibilities and crystal structures

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