Desflurane Versus Sevoflurane to Reduce Blood Loss in Maxillofacial Surgery

Rossi, Alessandro; Falzetti, Gabriele; Donati, Abele; Orsetti, G.; Pelaia, P

doi:10.1016/j.joms.2008.12.012

Cited by 19 publications

(14 citation statements)

References 18 publications

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“…120 The effects were attributed to the enhanced stress response in patients undergoing anesthesia with a volatile agent. 120 Volatile anesthetics also often cause hypotension and transient hypoxia, 126,127 which promote tissue inflammation and increase cellular adhesion. These can, in turn, depress the T h 1 phenotype or promote cell-mediated immunity.…”

Section: Indirect Effectors Of Immunitymentioning

confidence: 99%

Immune Modulation by Volatile Anesthetics

et al. 2016

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Volatile general anesthetics continue to be an important part of clinical anesthesia worldwide. The impact of volatile anesthetics on the immune system has been investigated at both mechanistic and clinical levels, but previous studies have returned conflicting findings due to varied protocols, experimental environments, and subject species. While many of these studies have focused on the immunosuppressive effects of volatile anesthetics, compelling evidence also exists for immunoactivation. Depending on the clinical conditions, immunosuppression and activation due to volatile anesthetics can be either detrimental or beneficial. This review provides a balanced perspective on the anesthetic modulation of innate and adaptive immune responses as well as indirect effectors of immunity. Potential mechanisms of immunomodulation by volatile anesthetics are also discussed. A clearer understanding of these issues will pave the way for clinical guidelines that better account for the impact of volatile anesthetics on the immune system, with the ultimate goal of improving perioperative management.

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Section: Indirect Effectors Of Immunitymentioning

confidence: 99%

Immune Modulation by Volatile Anesthetics

et al. 2016

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“…27,29 Two studies had included HA as a part of the main predictive variable. 22,24 Rossi et al 24 examined 2 types of hypotensive anesthetic methods and found the use of remifentanil and desflurane as a part of a balanced HA, in contrast to the combination of remifentanil and sevoflurane, reduced IOB by approximately 25% (7.2 AE 2.8 vs 9.6 AE 3.7 mL/kg, P < .038). Enlund et al 22 found no significant decrease in total IOB Q3 when comparing normotensive and HA.…”

Section: Quality Assessmentmentioning

confidence: 99%

Prevention of Bleeding in Orthognathic Surgery—A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Olsen

Skov

Ingerslev

et al. 2016

Journal of Oral and Maxillofacial Surgery

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“…In maxillofacial surgery, in which the surgical view is again of great importance, desflurane and sevoflurane were compared by Rossi et al [15], and the amount of bleeding was measured in two groups with similar hemodynamic status. They reported that desflurane provides a better surgical view, by causing a lower amount of bleeding.…”

Section: Discussionmentioning

confidence: 99%