Desflurane requirements for laryngeal mask airway insertion during inhalation induction

Abstract

We demonstrated that N(2)O-desflurane inhalation induction with a normal tidal breathing technique after premedication with fentanyl can be used safely without any adverse airway events in nonparalyzed patients. In such patients, the EC(50) of desflurane for successful LMA insertion was 3.61 +/- 0.31% (95% CI, 3.13-3.90).

Desflurane Inhalation Provide Cardiovascular Stability During Intubation but Prevention of Rocuronium Injection Pain

“…Therefore they have a general tendency to start desflurane inhalation after tracheal intubation. But several studies [6][7][8][9] have demonstrated that desflurane can be used in inhalation induction. We hypothesized that early inhalation of desflurane would be good for cardiovascular stability during intubation and also rocuronium injection pain.…”

“…Many studies [8,9] used desflurane as induction agent showed a stepwise increase in desflurane for example desflurane was gradually increased by 1% every six breaths until the expiratory desflurane concentration reached 10% or desflurane was increased by 1% every 1 min, to a maximum of 6%. But we used desflurane vaporizer (D-vapor, Drager, Germany) was starting at 6%.…”