Desensitization therapy for elevated donor-specific antibody levels in haploidentical transplantation in Chilean patients
Mauricio Sarmiento,
Emilio Salinas,
Patricio Rojas
et al.
Abstract:Allogeneic stem cell transplantation (ALOSCT) is curative for several hematological diseases. Unrelated donors and cord blood stem cells are valid options but haploidentical donors (HAPLO) have been considered the main source of stem cells in several countries, partly due to easy access and low cost of the transplantation process. Unfortunately, some patients have antibodies against the HLA epitopes from family haploidentical donors (donor-specific antibodies [DSA]) which are associated with engraftment failur… Show more
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