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Cited by 6 publications
(7 citation statements)
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“…To date, only a handful of Theraphosidae venoms have been extensively characterized, including the venoms of the Chinese black earth tiger tarantula C. hainanus ( H. hainanum ), C. schmidti ( H. schmidti ), and C. guangxiensis , among others [28]. P. verdolaga is a recently described Theraphosidae spider distributed mainly in the region of Antioquia (Colombia) [29]. MS/MS and transcriptomics analyses of the venom-gland content showed that P. verdolaga venom is not only composed of theraphotoxins, but also by larger proteins, in agreement with what has been previously reported for tarantulas [17].…”
Section: Discussionmentioning
confidence: 99%
“…To date, only a handful of Theraphosidae venoms have been extensively characterized, including the venoms of the Chinese black earth tiger tarantula C. hainanus ( H. hainanum ), C. schmidti ( H. schmidti ), and C. guangxiensis , among others [28]. P. verdolaga is a recently described Theraphosidae spider distributed mainly in the region of Antioquia (Colombia) [29]. MS/MS and transcriptomics analyses of the venom-gland content showed that P. verdolaga venom is not only composed of theraphotoxins, but also by larger proteins, in agreement with what has been previously reported for tarantulas [17].…”
Section: Discussionmentioning
confidence: 99%
“…Finally, we found two more sequences that have the multicopper oxidase domine present (PF07732) (see Table 1 H) and one more similar to the zinc metalloproteases that would be an important modulator of the hemostatic system [ 7 ] (see Table 1 I). Based on phylogenetic analysis, P. verdolaga metalloproteinase is related to A. ventricosus (branch support 44%) (see Figure S3 on Supplementary File S1 ).…”
Section: Resultsmentioning
confidence: 99%
“…Lycotoxins are a wide group of peptides that function as insecticides and pore formers, increasing the membrane permeability and cell lysis widely reported in the Lycosa genera [ 35 , 36 ]. Other HMMCs found in P. verdolaga venom with clinical importance are those with the domain multicopper oxidase and the venom metalloproteinases, which can attack the hemostatic system of prey [ 7 ].…”
Section: Discussionmentioning
confidence: 99%
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