Descensus Averno

Thymic targets for Abelson murine leukemia virus are early gamma/delta T lymphocytes.

“…We and others (22) have observed that Ab-MuLV(q-2) efficiently induces thymomas in weanling B6 mice; 31 of 64 (48%) mice injected intrathymically with Ab-MuLV(q-2) developed thymomas 22-50 days after injection. The Ab-MuLV proviral integration patterns of 17 of these tumors and of eight thymomas induced by AbMuLV(Mo-MuLV) were analyzed by digestion of the DNAs with EcoRI, which permits the detection of unique proviral integration fragments (11).…”

Leukemia initiated by hemopoietic stem cells expressing the v-abl oncogene.

“…All experiments in this report were done by using the new virus stock, which had a titer of 1 X 107 focus-forming units per ml. The helper-free status of the A-MuLV virus stock was confirmed by the XC plaque assay as reported (15,20).…”

Polyhydroxybutyrate, a Biodegradable Thermoplastic, Produced in Transgenic Plants

“…E n m e activitv was not detectable in leaf extracts of the untransformed wild-type plants. Leaf extracts of the seven transgenic lines exhibited specific activities ranging from 1.6 to 16.2 units per milligram of protein (12), compared to 1.4 units per milligram of protein for extracts of Escherichia coli DH5a that ex~ressed the bhbB mozygous transgenic lines dbtained by transformation with the phbB gene indicated the proper integration and transcription of the gene in the various lines (10). To assess whether the phbB mRNA was correctly translated and whether the polypeptide produced was functional, we assayed transgenic plants that had the phbB gene for activity in transgenic plants that contained the phbC gene was not considered an accurate reflection of whether the enzyme would function in plants that contained the additional enzymes of the pathway.…”