“…Splanchnic and cerebral perfusion during arch reconstruction, avoidance of deep hypothermia (and its attendant coagulopathy, disruption of cellular homeostasis, and autoregulation), and judicious blood product control have shown decreased renal insult, decreased respiratory compromise, decreased perioperative instability, and have even made feasible the extubation of Norwood patients in the operating room. 13 Early separation from mechanical ventilation, minimal blood product transfusion, avoidance of deep hypothermia, continuous splanchnic, and cerebral perfusion during arch reconstruction show progress toward lower overall operative insult, shorter duration of mechanical ventilation, shorter ICU stay, and fewer complications, which are all shown to affect transplant-free survival. 13,14 The SVR data set continues to point to center differences that cloud the question of shunt type as a determinant of risk.…”