Dermoscopy of Primary Cutaneous Amyloidosis in Skin of Color

Kaliyadan, Feroze; Alkhateeb, Abdulaziz; Kuruvilla, Joel; Swaroop, Krishna; Alabdulsalam, Abdulrahim A.

doi:10.5826/dpc.0903a17

Cited by 5 publications

(9 citation statements)

References 6 publications

(1 reference statement)

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“…Most common dermoscopy findings were sulcus cutis and crista cutis seen in all patients (100% and 99% [37][38][39] Thus this obviates the need for histopathology and other systemic investigations in such patients. Dermoscopy is a potential technique which is noninvasive for the diagnosis, prognosis, and monitoring of pigmentary disorders.…”

Section: Out Of 103 Patients 62 Patients Underwent Biopsy a Correlationmentioning

confidence: 99%

Therapeutic implications of dermoscopic findings in acanthosis nigricans: A clinical and histopathological study

Pardeshi

Khemani

Kamath

et al. 2020

Dermatologic Therapy

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Acanthosis nigricans is associated with numerous systemic disorders. These include endocrinological conditions such as, diabetes, acromegaly, Cushing's syndrome, thyroid dysfunction, as well as metabolic abnormalities like obesity and polycystic ovarian disease. Its association with visceral malignancy is known. Moreover, Acanthosis nigricans is known to be a cutaneous marker of insulin resistance (IR) and hyperinsulinemia. The primary aim of this study was to study clinical and histopathological patterns of acanthosis nigricans and its correlation with dermoscopic patterns and treatment implications. 103 patients clinically diagnosed as acanthosis nigricans were enrolled in the study. Clinical evaluation, dermoscopy, and skin biopsy was done for histopathological evaluation. Consistency was observed in the changes seen on dermoscopy with clinical and histopathological findings. Common dermoscopy findings were Crista Cutis, Sulcus Cutis, Papillary projections, hyperpigmented dots, crypts, and blotching Dermoscopic findings can be correlated with histopathological features. Dermoscopy allows visualization on higher magnification which helps to pick up subtle changes which are not visible to naked eye. Dermoscopy can be a useful tool to distinguish acanthosis nigricans from other pigmentary disorders in patients who are not willing for histopathological examination and helps in treatment making decisions.

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Section: Out Of 103 Patients 62 Patients Underwent Biopsy a Correlationmentioning

confidence: 99%

Therapeutic implications of dermoscopic findings in acanthosis nigricans: A clinical and histopathological study

Pardeshi

Khemani

Kamath

et al. 2020

Dermatologic Therapy

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“…In particular, radial streaks and venation were not seen. [ 4 ] It is noteworthy that streaks were similarly not well-visualized in our cases too. Even when seen, they were irregular and often broken [ Figure 2a ].…”

mentioning

confidence: 51%

“…[ 3 ] Further, the published indexed literature on dermoscopy of MA in patients with skin of color (SOC) is scarce, excepting for the singular case report by Kaliyadan et al . on dermoscopic features of PCA (biphasic) described in a 57-year-old Indian woman with SPT V.[ 4 ] While authors observed areas corresponding to the pattern described by Chuang et al . in the form of white hubs surrounded by different patterns of hyperpigmentation, the specific morphology and amount of pigmentation were different.…”

mentioning

confidence: 99%

Dermoscopy of Macular Amyloidosis

Sonthalia¹,

Agrawal

Sehgal³

2021

Indian Dermatology Online Journal

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“…Informaron, en un estudio de 35 casos, que en la variedad macular los patrones primarios observados incluían un centro blanco o marrón, rodeado de varias configuraciones de hiperpigmentación y para casos con hiperqueratosis prominente como en la amiloidosis liquenoide, el centro era reemplazado por una área blanca cicatrizal. 18…”

Section: Diagnósticounclassified

Manifestaciones dermatológicas en amiloidosis secundaria a mieloma múltiple

Ramos¹,

Rivero²,

Santos³

2021

Acta Médica Grupo Ángeles

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El mieloma múltiple (MM) es una enfermedad maligna de células plasmáticas de linfocitos; B. Bluefarb estimó que aproximadamente el 15% de los pacientes con MM desarrollarán alguna forma de amiloidosis. El término amiloidosis hace referencia a la acumulación extracelular de un material amiloide, debido a un mal plegamiento de las proteínas autólogas. El subtipo de amiloidosis de cadenas ligeras lambda (AL) es el más común en amiloidosis cutánea asociada con MM. En México, la frecuencia de amiloidosis cutánea en la consulta dermatológica es de aproximadamente 0.5% y predomina en mujeres. La infiltración de tejido por estos depósitos de amiloide se produce de forma localizada o sistémica. Cuando la amiloidosis afecta la piel, puede ser como una manifestación de amiloidosis sistémica, o una amiloidosis cutánea localizada. Las enfermedades amiloides cutáneas pueden tener manifestaciones heterogéneas, dependiendo de la ubicación del depósito amiloide dentro de la dermis o la epidermis. El diagnóstico de amiloidosis se realiza histológicamente mediante la demostración del depósito de amiloide. El tratamiento de la amiloidosis va enfocado a cada tipo. Los pacientes con mieloma asociado con amiloidosis AL con afectación de la piel tienen el peor pronóstico.

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Dermoscopy of Primary Cutaneous Amyloidosis in Skin of Color

Cited by 5 publications

References 6 publications

Therapeutic implications of dermoscopic findings in acanthosis nigricans: A clinical and histopathological study

Therapeutic implications of dermoscopic findings in acanthosis nigricans: A clinical and histopathological study

Dermoscopy of Macular Amyloidosis

Manifestaciones dermatológicas en amiloidosis secundaria a mieloma múltiple

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