Dermoscopy of pagetoid reticulosis, with dermoscopic‐pathologic correlation

Abstract

Pagetoid reticulosis (PR), also known as Woringer‐Kolopp disease, is a rare variant of mycosis fungoides with distinctive clinicopathologic features. It clinically manifests as a solitary, erythematous, gradually enlarging, scaly, or verrucous plaque on the lower extremities, and due to its indolent course and nonspecific clinical features, may remain undiagnosed for years. In the current study, we describe the clinical and dermoscopic characteristics of a rare case of PR disease and correlate them with the corresponding histopathologic findings. Dermoscopy may prove beneficial in early diagnosis of this rare entity.

Dermoscopic and trichoscopic features of primary cutaneous lymphomas – systematic review

“…showed repetitive dermoscopic pattern of dotted/glomerular vessels, pink background and white scale. Similar features were observed also by Manoli et al 31 …”

“…Dermoscopy Cases reported by Suzaki et al 29 and Morariu et al 30 showed repetitive dermoscopic pattern of dotted/glomerular vessels, pink background and white scale. Similar features were observed also by Manoli et al 31 According to the authors, dotted and glomerular vessels correspond with hypertrophic vessels of the papillary dermis, whitish halowith hyperplastic epithelium, while red dots with hyperplastic vessels located at the top of the elongated dermal papillae. 25 Different patternwith white-pink structureless central area and brown peripheral lines associated with linear vesselswas presented by di Meo et al 32 Primary cutaneous anaplastic large cell lymphoma (PCALCL)…”

Not Every Isolated Plantar Lesion Is a Wart: A Case of Pagetoid Reticulosis Presenting as an Acral Lesion

“…In this case dermoscopy showed a white hyperkeratotic center, aligned red dots, and slight-pinkish background. Prior reports of PR described regular dotted and glomerular vessels in a pinkish background, vessels halos, and scales [1].…”

“…PR is a rare variant of mycosis fungoides, manifesting as solitary indolent scaly or verrucous plaque frequently misdiagnosed as dermatitis or psoriasis [1]. Dermoscopy provides diagnostic clues: plantar warts show disruption of dermatoglyphics and irregular capillaries due to weight bearing and trauma; calluses demonstrate homogenous opacities; corns exhibit a translucent core; Bowen disease has scale and glomerular vessels in clusters [2].…”

Pagetoid reticulosis

“…В инфильтрате отмечают тенденцию к мономорфности клеток, но могут наблюдаться незначительный полиморфизм и гиперхромазия, а также единичные клетки с церебриформными ядрами, характерные для классической формы грибовидного микоза. Выраженный акантоз и волнистость эпидермиса, в ряде случаев приводящие к веррукозной гиперплазии, тоже являются характерными гистопатологическими признаками ПР [10,11]. Дифференциальная диагностика ПР проводится с заболеваниями папулосквамозного, неопластического и инфекционного характера: экземой, псориазиформным дерматитом, бородавчатым туберкулезом кожи, Литература/References бластомикозом, лейшманиозом, дерматофитиями и др.…”