Dermoscopy of Merkel Cell Carcinoma

Dalle, S.; Parmentier, Laurent; Moscarella, Elvira; Phan, Alice; Argenziano, Giuseppe; Thomas, Luc

doi:10.1159/000337411

Cited by 47 publications

(34 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…had no cases demonstrating structureless areas . Structureless areas were not scored by Dalle et al . All MCCs in our series had structureless areas in our opinion.…”

Section: Discussionsupporting

confidence: 83%

Clinical and dermoscopic characteristics of Merkel cell carcinoma

et al. 2013

View full text Add to dashboard Cite

show abstract

“…had no cases demonstrating structureless areas . Structureless areas were not scored by Dalle et al . All MCCs in our series had structureless areas in our opinion.…”

Section: Discussionsupporting

confidence: 83%

Clinical and dermoscopic characteristics of Merkel cell carcinoma

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Both are non-pigmented nodules that commonly contain linear irregular vessels [36,37]. However, other vascular features may help discriminate, with hairpin vessels favoring the diagnosis of SCC and arborizing vessels favoring the diagnosis of Merkel cell carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Dermoscopic characteristics of nodular squamous cell carcinoma and keratoacanthoma

Lin

Pan

Jalilian³

et al. 2014

Dermatol Pract Concept

View full text Add to dashboard Cite

Background:Nodular squamous cell carcinoma (SCC) and keratoacanthoma (KA) may mimic a variety of other benign and malignant non-pigmented nodules.Objectives:To analyze the dermoscopic characteristics of nodular SCC and KA.Patients/Methods:Retrospective analysis of 50 nodular SCCs and 8 KAs collected from a tertiary dermatology referral center and a private dermatology practice in Melbourne, Australia, between 1 September 2009 and 1 October 2012. All lesions were nodules; defined as firm, elevated, round, palpable tumors with a diameter of 5 mm or more. Clinical and dermoscopic images were evaluated by two examiners in consensus.Results:Signs of keratinization were frequently observed and included keratin crust/scale (90% of SCCs, 100% of KAs), central keratin mass (32% of SCCs, 88% of KAs), white structureless areas (66% of SCCs, 50% of KAs), white circles (32% of SCCs, 38% of KAs) and white keratin pearls (14% of SCCs, 12% of KAs). Hemorrhage was present in 72% of SCCs and 88% of KAs and preferentially occurred centrally and in areas of keratinization. For nodular SCCs and KAs, we observed glomerular vessels (42% and 25% respectively), linear irregular vessels (36% and 25% respectively), atypical vessels (30% and 38% respectively) and hairpin vessels (30% and 25% respectively).Conclusions:Hemorrhage, keratinization and vascular features (glomerular, hairpin and linear irregular morphologies) are useful in diagnosing both nodular SCC and KA. Further research on the comparative dermoscopic characteristics of a range of amelanotic nodules is important in order to improve diagnosis of these clinically challenging tumors.

show abstract

“…There were some reports of non-BCC with AV (Table 2)34567891011121314. According to the keywords, 9 of 81 articles found with “arborizing vessel,” 8 of 21 articles with “arborizing vessel AND dermoscopy,” and 10 of 250 articles with “vascular AND dermoscopy” were included.…”

Section: Resultsmentioning

confidence: 99%

Arborizing Vessels on Dermoscopy in Various Skin Diseases Other Than Basal Cell Carcinoma

et al. 2017

View full text Add to dashboard Cite

BackgroundArborizing vessels (AVs) are dermoscopically defined as telangiectasias with distinct treelike branching, and are a characteristic feature of basal cell carcinoma (BCC). However, AVs are observed in various conditions other than BCC.ObjectiveThe aim of this study was to investigate skin diseases showing AV and investigates dermoscopic differences between BCC and non-BCC.MethodsDermoscopic images showing AV were prospectively collected and classified into BCC/non-BCC. Non-BCC was further classified into tumors (benign cystic, benign non-cystic, premalignant, and malignant) and non-tumors. We compared AV focusing, widest diameter of stem vessels, widest diameter ratio of stem vessel to first branch, and number of ramifications between groups.ResultsAmong 124 images, 54.0% were BCC and 46.0% were non-BCC. Non-BCC included epidermal cysts, hypertrophic scars/keloids, intradermal nevi, actinic keratoses, etc. The proportion of focused AV in BCC was significantly higher and the proportion of unfocused AV in BCC was lower than that of premalignant and malignant non-BCC. The widest diameter ratio of stem vessel to first branch was higher in non-BCC. Number of ramifications was significantly less in benign cystic non-BCC than BCC.ConclusionVarious skin diseases showed AV, so that diagnoses other than BCC should be considered. The findings in this study could help discriminate BCC from non-BCC.

show abstract

Dermoscopy of Merkel Cell Carcinoma

Cited by 47 publications

References 39 publications

Clinical and dermoscopic characteristics of Merkel cell carcinoma

Clinical and dermoscopic characteristics of Merkel cell carcinoma

Dermoscopic characteristics of nodular squamous cell carcinoma and keratoacanthoma

Arborizing Vessels on Dermoscopy in Various Skin Diseases Other Than Basal Cell Carcinoma

Contact Info

Product

Resources

About