Dermatoscopy of a minute melanoma

Rosendahl, Cliff; Cameron, Alan; Bulinska, Agata; Williamson, Richard; Kittler, Harald

doi:10.1111/j.1440-0960.2010.00725.x

Cited by 14 publications

(18 citation statements)

References 9 publications

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“…Previously the dermatoscopic features of an in-situ melanoma with a diameter of 1.6 mm were reported [7]. Published dermatoscopy images revealed that even at this minute size there was unequivocal asymmetry of structure and the presence of the dermatoscopic clue to melanoma of gray dots.…”

Section: Discussionmentioning

confidence: 99%

A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

Pellizzari¹,

Magee

Weedon

et al. 2013

Dermatol Pract Concept

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We present a case of an early invasive melanoma (Breslow thickness 0.25 mm), 1.6 mm in diameter on the arm of a 38-year-old woman. She was under surveillance due to having multiple (>100) nevi, and the melanoma was assessed as a new lesion by the examining doctor. Clinically the lesion was hyper-pigmented compared with surrounding nevi and dermatoscopically it had a clue of pseudopods/lines radial, but they were arranged in an arguably symmetrical circumferential pattern around a structureless blue-gray center. Generally melanomas are expected to be dermatoscopically asymmetrical, but we believe that this case illustrates the fact that small melanomas may be recognized by clues such as pseudopods/lines radial and dermatoscopic gray even when they have not yet developed unequivocal asymmetry.

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Section: Discussionmentioning

confidence: 99%

A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

Pellizzari¹,

Magee

Weedon

et al. 2013

Dermatol Pract Concept

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“…It has previously been reported that small melanomas may not be asymmetrical [1,2]. It has also been reported that hyperpigmentation was the defining feature in all of 13 small melanomas (<4 mm diameter) in one series of 95 melanomas [12], but Pellizzari et al pointed out that this may in fact be due to selection bias, with darker lesions being discovered, while paler, hypomelanotic lesions may not be suspected at the stage where they are very small [2].…”

Section: Discussionmentioning

confidence: 99%

“…Small melanomas (diameter < 4 mm) present diagnostic difficulties, as the clinical and dermatoscopic characteristics of such lesions have been reported only rarely [1]. Another recent case report by Pellizzari et al suggests that in very small lesions chaos (asymmetry of structure or color) may not be unequivocally present [2].…”

Section: Introductionmentioning

confidence: 99%

When algorithms falter: a case report of a very small melanoma excised due to the dermatoscopic “ugly duckling” sign

Inskip¹,

Magee

Weedon

et al. 2013

Dermatol Pract Concept

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We present a case report of a 3.5 mm diameter superficial spreading melanoma on the upper back of a 27-year-old woman, signed out as Clark level 2, Breslow thickness 0.2 mm with regression to 0.45 mm. The patient, with Fitzpatrick type 1 skin and minimal actinic damage, had presented for a routine skin check with no previous history of skin cancers. At the age of 17 she had received chemotherapy and radiotherapy for Ewing’s sarcoma of the right hip with pulmonary metastases. The skin lesion was assessed as dermatoscopically symmetrical and was not predicted as a melanoma by any algorithmic method. The provisional diagnosis of melanoma was made on the basis that this lesion was completely different in dermatoscopic pattern to her other nevi, a dermatoscopic “ugly duckling” lesion. We draw attention to the recently established link between defects in the STAG2 gene and Ewing’s sarcoma, glioblastoma and melanoma.

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“…Gray structures, and more specifically gray circles, have been described as a clue to melanoma [7,8] correlating with extension of melanin-containing melanoma cells down hair follicles, and asymmetrically pigmented follicular openings are described as a clue to lentigo maligna [9]. Furthermore it has been recommended that the presence of any dermatoscopic gray structures on the face should lead to a biopsy [6]. …”

Section: Case Reportmentioning

confidence: 99%

“…Currently, few very small melanomas are diagnosed [4,5]. The increased use of dermatoscopy and digital monitoring should lead to more small melanomas being encountered [6]. What is not known is how commonly these very small melanomas, at the ‘infantile’ stage of Ackerman’s analogy, lack sufficient criteria to make the diagnosis of melanoma.…”

Section: Introductionmentioning

confidence: 99%