Dermatoscopy in vulvar basal cell carcinoma

Vukojević, Danijela Dobrosavljević; Djurisic, Igor; Lukic, Silvana; Kastratović-Kotlica, Biljana; Vukičević, Jelica

doi:10.1111/jdv.13895

Cited by 8 publications

(10 citation statements)

References 9 publications

(15 reference statements)

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“…In the cases presented here, the presence of reddish and well-focused arborizing telangiectasia was a relevant clue to the diagnosis. Interestingly, both of our cases and one previously reported [ 6 ] showed prominent homogeneous whitish areas, which could be an additional clue for vulvar BCC. We hypothesize that these whitish areas could correlate with a peritumoral fibrosis that could be more visible on mucosa compared to the skin due to the absence of the stratum corneum and to the thinner epithelium.…”

Section: Discussionsupporting

confidence: 74%

“…Non-invasive imaging techniques, such as dermoscopy and RCM, are of great interest since they orient the diagnosis of this rare tumor in this sensitive area. The dermoscopic features of our cases and of the previously reported two patients with vulvar BCC [ 6 , 8 ] showed blue ovoid nests and telangiectasia as extragenital BCC. The previously published cases were both pigmented [ 6 , 8 ], whereas one of our cases was a non-pigmented BCC.…”

Section: Discussionsupporting

confidence: 71%

“…The dermoscopic features of our cases and of the previously reported two patients with vulvar BCC [ 6 , 8 ] showed blue ovoid nests and telangiectasia as extragenital BCC. The previously published cases were both pigmented [ 6 , 8 ], whereas one of our cases was a non-pigmented BCC. In the case of pigmented BCC, ovoid nests allow for diagnosis of this tumor easily.…”

Section: Discussionsupporting

confidence: 71%

“…Vulvar BCC can mimic inflammatory diseases such as eczema, psoriasis, and infections (chronic candidiasis). It can also simulate Bowen disease, Paget disease, squamous cell carcinoma, leukoplakia, lichen ruber planus, lichen sclerosus, melanocytic nevus, melanoma, seborrheic keratosis, angioma, and other pigmented and non-pigmented tumors [ 6 ]. Therefore, the diagnosis is frequently delayed and it is usually performed after inappropriate treatment [ 2 , 3 ].…”

Section: Discussionmentioning

confidence: 99%

“…Dermoscopic features of vulvar BCC have been reported in only two cases, but RCM features have not been reported yet [ 6 , 8 ]. Non-invasive imaging techniques, such as dermoscopy and RCM, are of great interest since they orient the diagnosis of this rare tumor in this sensitive area.…”

Section: Discussionmentioning

confidence: 99%

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Dermoscopic and reflectance confocal microscopy features of two cases of vulvar basal cell carcinoma

Cinotti

Tonini

Perrot

et al. 2018

Dermatol Praat Concept

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Basal cell carcinoma (BCC) is the most common malignant skin cancer. Its genital localization is rare, and the diagnosis in this site could be challenging. Here, we report two patients with vulvar BCC and describe their clinical, dermoscopic and in vivo and ex vivo reflectance confocal microscopic (RCM) features. Dermoscopy and RCM can be useful tools for helping the clinical diagnosis of vulvar BCC and for identifying the correct surgical margins.

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Section: Discussionsupporting

confidence: 74%

Section: Discussionsupporting

confidence: 71%

Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Dermoscopic and reflectance confocal microscopy features of two cases of vulvar basal cell carcinoma

Cinotti

Tonini

Perrot

et al. 2018

Dermatol Praat Concept

View full text Add to dashboard Cite

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Diagnosis and management of vulvar cancer: A review

Tan

Bieber

Stein

et al. 2019

Journal of the American Academy of Dermatology

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Dermatoscopy in the Diagnosis of Vulvar Basal Cell Carcinoma: A Case Report

Davalos¹,

Cepeda‐Valdés²,

Favela-Fernandez³

et al. 2021

Int J Dermatol Venereol

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Introduction: Basal cell carcinoma (BCC) is the most common human malignancy commonly in white people, but in less than 1% of cases it may appear on unexposed areas, like the perineal and anal regions. Vulvar BCC is often diagnosed late because it grows slowly and tends to be asymptomatic, with no specific physical findings.Here, we present a rare Latin patient with a 10-year history of vulvar BCC with dermatoscopic and histopathologic findings.Case report: A 65-year-old Latin woman presented with a nodule on her left labium majus, which she first noted 10 years ago, and that had grown slowly but constantly. She also reported a 20-year history of pruritus and occasional pain. Physical examination showed a 3.5 cm Â 3.0 cm erythematous lesion with a central rough without inguinal lymphadenopathy. Contact dermatoscopy (Dermalite DL3 Gen.) showed one blurred cluster of arborising vessels in a pinkish background with white homogeneous areas and lines radial converging. An incisional biopsy was realized, and histopathology diagnosed BCC.Discussion: Vulvar BCC is a rare malignancy that affects mainly Caucasian women over 70 years of age. The most common etiology for BCC is ultraviolet radiation, but as the vulva is unexposed its cause is unclear. Mutations in tumor suppressor and regulatory genes such as p53 are present in 50% of cases. Gorlin syndrome, chronic radiation, chronic arsenic exposure, xeroderma pigmentosum, and immunosuppression have been considered as risk factors. Conclusion:Vulvar BCC characteristics are the same as other cutaneous forms, featuring blue ovoid nests and arborizing telangiectasia, confused with inflammatory diseases, such as eczema, psoriasis, and chronic infection (especially if it is accompanied by pruritus), this makes diagnosis complex, with a delay of 5 to 6 years on average, with an average size of 2.1 cm. Diagnosis is enhanced with dermatoscopy, as the preferred treatment for most BCC cases is wide surgical excision.

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Dermatoscopy in vulvar basal cell carcinoma

Cited by 8 publications

References 9 publications

Dermoscopic and reflectance confocal microscopy features of two cases of vulvar basal cell carcinoma

Dermoscopic and reflectance confocal microscopy features of two cases of vulvar basal cell carcinoma

Diagnosis and management of vulvar cancer: A review

Dermatoscopy in the Diagnosis of Vulvar Basal Cell Carcinoma: A Case Report

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