2010
DOI: 10.1111/j.1468-3083.2010.03929.x
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Dermatomyositis related to autoimmune thyroiditis

Abstract: Prevalence of cancer in coexistent DM and AIT may be very low. Also, it is reasonable to suggest that DM patients with AIT should be routinely evaluated for thyroid function and the emergence of comorbidities. Moreover, corticosteroids combined with levothyroxine may be useful for these patients as a standard treatment.

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Cited by 9 publications
(9 citation statements)
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References 48 publications
(53 reference statements)
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“…The fatigue‐associated variables such as thyroid disease in ADM and female sex in SLE are consistent with past studies. Fatigue is a hallmark symptom in thyroid disease, and autoimmune thyroid dysfunction is particularly common in dermatomyositis . Fatigue has also been found to be more prevalent in women …”
Section: Discussionmentioning
confidence: 99%
“…The fatigue‐associated variables such as thyroid disease in ADM and female sex in SLE are consistent with past studies. Fatigue is a hallmark symptom in thyroid disease, and autoimmune thyroid dysfunction is particularly common in dermatomyositis . Fatigue has also been found to be more prevalent in women …”
Section: Discussionmentioning
confidence: 99%
“…Given the known association of autoimmune thyroiditis with DM, the patient was likely genetically predisposed to DM development, and lacosamide may have acted as an environmental trigger. 6 Lacosamide, a third-generation antiepileptic drug (AED), acts on neuronal voltage-gated sodium channels and has only been previously described to cause cutaneous manifestations through hypersensitivity reactions. 7 The mechanism for drug-induced DM remains unclear; however, it has been proposed that certain drugs may inflict damage to endothelial cells leading to release of cellular antigens and epitope spreading, which causes an autoimmune reaction.…”
Section: Discussionmentioning
confidence: 99%
“…It is possible that our patient also had a history of autoimmune thyroiditis, given the elevated antithyroperoxidase antibody. Interestingly, several case reports have described an association between DM and autoimmune thyroiditis 11 12. Wang et al 12 identified 3 of 11 patients in their review of DM and autoimmune thyroiditis who had thyroidectomy for nodular goitres before a diagnosis of DM was made.…”
Section: Discussionmentioning
confidence: 99%
“…Interestingly, several case reports have described an association between DM and autoimmune thyroiditis 11 12. Wang et al 12 identified 3 of 11 patients in their review of DM and autoimmune thyroiditis who had thyroidectomy for nodular goitres before a diagnosis of DM was made. One patient in this retrospective review had non-Hodgkin's lymphoma but it is unclear what nodal sites or organs were involved.…”
Section: Discussionmentioning
confidence: 99%