Dermatomyositis: a comprehensive review of clinical manifestations, serological features, and therapeutic approaches

Didona, Dario; Solimani, Farzan; Caposiena, Raffaele Dante; Santos, Antonio Manuel Sequeira; Hinterseher, Julia; Kussini, Jacqueline; Cunha, Tomas; Hertl, Michael; Didona, Biagio

doi:10.23736/s2784-8671.23.07458-3

Cited by 2 publications

(4 citation statements)

References 107 publications

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“…Some patients may have no muscle weakness while others may have minimal or diffuse muscle weakness. 7 More than 85% of dermatomyositis patients with muscle weakness have elevated serum creatinine kinase levels. 8 In a dermatomyositis suspected patient, detailed evaluation of their history and a physical examination emphasizing skin inspection and assessment of muscle strength are necessary.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Thyroid Neoplasm-Associated Dermatomyositis in Ethiopian Woman

Legese,

Tesfaye,

Ayele

et al. 2024

IMCRJ

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Background Dermatomyositis is an inflammatory myopathies causing proximal muscle weakness accompanied by muscular inflammation and skin rash. Dermatomyositis patients have a higher incidence of malignancy as compared to the general population. Case Report A 52-year-old known female patient with a toxic multi-nodular goiter presented with insidious onset of itchy erythematous rash on her neck and bilateral hands and progressive muscle weakness of 4 months’ duration. Associated with this, she had photosensitivity, and periorbital edema of 2 months’ duration. On physical examination, she had an anterior neck mass, proximal muscle weakness, periorbital edema, and violaceous skin rash on her bilateral arms, shoulders and neck. Thyroid function tests were normal, creatinine kinase was elevated, and muscle biopsy revealed inflammatory myositis. Ultrasound of the anterior neck mass and analysis of fine needle aspiration suggested thyroid cancer. Conclusion A high index of clinical suspicion is usually required for early diagnosis of dermatomyositis in resource-limited settings in order to prevent adverse outcomes and identify associated malignancies.

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Section: Discussionmentioning

confidence: 99%

Diagnosis of Thyroid Neoplasm-Associated Dermatomyositis in Ethiopian Woman

Legese,

Tesfaye,

Ayele

et al. 2024

IMCRJ

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“…Dermatomyositis is an autoimmune disease that belongs to the group of collagen diseases (Diffuse Connective Tissue Diseases [CTDs]). 1 There are four main variants of dermatomyositis, classic, amyopathic, paraneoplastic, and juvenile dermatomyositis. 1 Classic dermatomyositis is characterized by inflammation of the skin (“dermatous”) and the striated muscle (“myositis”).…”

mentioning

confidence: 99%

“… 1 There are four main variants of dermatomyositis, classic, amyopathic, paraneoplastic, and juvenile dermatomyositis. 1 Classic dermatomyositis is characterized by inflammation of the skin (“dermatous”) and the striated muscle (“myositis”). 1 Among various skin manifestations, heliotrope rash and violaceous papules located at the interphalangeal or metacarpophalangeal joints (Guttron's papules) are the most common.…”

mentioning

confidence: 99%

“… 1 Classic dermatomyositis is characterized by inflammation of the skin (“dermatous”) and the striated muscle (“myositis”). 1 Among various skin manifestations, heliotrope rash and violaceous papules located at the interphalangeal or metacarpophalangeal joints (Guttron's papules) are the most common. 1 Myositis presents with myalgia, proximal weakness, and elevated muscle enzymes.…”

mentioning

confidence: 99%

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NXP-2 positive dermatomyositis with marked dysphagia following an insect bite

Bombardi,

Scorza,

Finsterer

et al. 2024

Clinics

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Dermatomyositis: a comprehensive review of clinical manifestations, serological features, and therapeutic approaches

Cited by 2 publications

References 107 publications

Diagnosis of Thyroid Neoplasm-Associated Dermatomyositis in Ethiopian Woman

Diagnosis of Thyroid Neoplasm-Associated Dermatomyositis in Ethiopian Woman

NXP-2 positive dermatomyositis with marked dysphagia following an insect bite

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