Dermatomycosis in renal transplant recipients in Adana, Turkey

Polat, Esra; Demir, Erkan; İlkit, Macit; Aridogan, Ibrahim Atilla; Polat, Fatma; Erken, U.

doi:10.1111/j.1365-4632.2008.03599.x

Cited by 2 publications

(3 citation statements)

References 11 publications

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“…However, the prevalence of onychomycosis did not differ significantly between psoriasis patients and patients with other dermatologic diseases such as erysipelas, atopic dermatitis, eczema, scleroderma and bullous skin diseases . Length of time following kidney transplant, or time spent on dialysis appear to increase the risk of onychomycosis in renal transplant patients …”

Section: Discussionmentioning

confidence: 82%

“…The literature search yielded a total of 1914 articles after duplicates were deleted with 34 articles remaining after full‐text review (Fig. ) . The included studies, along with their respective prevalence estimates, are listed in Table .…”

Section: Resultsmentioning

confidence: 99%

“…42 Length of time following kidney transplant, or time spent on dialysis appear to increase the risk of onychomycosis in renal transplant patients. 47,48 All of the populations in this review had a higher prevalence of culture-confirmed toenail onychomycosis than the general population, with the exception of children. The increased rate of culture-confirmed toenail onychomycosis in these high-risk patient populations is likely due to impaired immunity, reduced peripheral circulation and alterations to the nail unit (trauma and/or onycholysis).…”

Section: Discussionmentioning

confidence: 95%

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The prevalence of culture‐confirmed toenail onychomycosis in at‐risk patient populations

Gupta

Daigle

Foley

2014

Acad Dermatol Venereol

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Onychomycosis is a fungal infection of the nail and is the most common nail affliction in the general population. Certain patient populations are at greater risk of infection and the prevalence of onychomycosis reported in the literature has yet to be summarized across these at-risk groups. We performed a systematic review of the literature and calculated pooled prevalence estimates of onychomycosis in at-risk patient populations. The prevalence of dermatophyte toenail onychomycosis was as follows: general population 3.22% (3.07, 3.38), children 0.14% (0.11, 0.18), the elderly 10.28% (8.63, 12.18), diabetic patients 8.75% (7.48, 10.21), psoriatic patients 10.22% (8.61, 12.09), HIV positive patients 10.40% (8.02, 13.38), dialysis patients 11.93% (7.11, 19.35) and renal transplant patients 5.17% (1.77, 14.14). Dialysis patients had the highest prevalence of onychomycosis caused by dermatophytes, elderly individuals had the highest prevalence of onychomycosis caused by yeasts (6.07%; 95% CI = 3.58, 10.11) and psoriatic patients had the highest prevalence of onychomycosis caused by non-dermatophyte moulds (2.49%; 95% CI = 1.74, 3.55). An increased prevalence of onychomycosis in certain patient populations may be attributed to impaired immunity, reduced peripheral circulation and alterations to the nail plate which render these patients more susceptible to infection.

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Section: Discussionmentioning

confidence: 82%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 95%

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The prevalence of culture‐confirmed toenail onychomycosis in at‐risk patient populations

Gupta

Daigle

Foley

2014

Acad Dermatol Venereol

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Hemodialysis and Kidney Transplantation as Predisposing Conditions to Onychomycosis

Filho

Ventura²,

Criado

et al. 2017

Nephron

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Background/Aim: Onychomycosis (OM) is one of the commonest superficial fungal infections. Patients undergoing hemodialysis (HD) treatment and kidney transplant recipients (KTR) are considered at risk of contracting fungal infections, but the few published data do not reach the conclusion of whether they are predisposed to OM. This study aimed to determine the prevalence and etiology of OM in these patients and to determine the antifungal susceptibility profile of the isolated fungal species. Methods: We recruited 149 HD patients, 187 KTR, and a control group comprising 174 patients attending an internal medicine service with other diseases than renal diseases. All patients underwent an examination of all toenails to check for the presence of OM. Antifungal susceptibility tests were performed following the Clinical and Laboratory Standards Institute (CLSI) recommendations. Results: The prevalence rates of OM in HD patients (23.4%) and KTR (23.0%) were significantly higher than those in age- and sex-matched control groups (13.2%). In HD patients, OM was associated with diabetes but not with the duration of dialysis. In KTR, OM was more prevalent in those without diabetes and likely also in those using mycophenolate mofetil or azathioprine but was not associated with the duration of transplantation. Trichophyton rubrum was the most prevalent species (45.9%) followed by T. mentagrophytes (24.5%) and Candida parapsilosis (18.0%). Fluconazole, itraconazole, voriconazole, and terbinafine were all efficient against the isolates of dermatophyte, with terbinafine showing the lowest and fluconazole the highest minimal inhibitory concentrations. All isolates of C. parapsilosis were sensitive to the antifungals according to the CLSI criteria. Conclusion: We found a high prevalence of OM in HD and KTR patients and suggest that these conditions should be considered a risk factor of OM. All 4 antifungals evaluated in the study showed good in vitro activity against the etiologic agents.

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Dermatomycosis in renal transplant recipients in Adana, Turkey

Cited by 2 publications

References 11 publications

The prevalence of culture‐confirmed toenail onychomycosis in at‐risk patient populations

The prevalence of culture‐confirmed toenail onychomycosis in at‐risk patient populations

Hemodialysis and Kidney Transplantation as Predisposing Conditions to Onychomycosis

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