Dermatology: how to manage acne vulgaris

Leung, Alexander K. C; Barankin, Benjamin; Lam, Joseph M.; Leong, Kin Fon; Hon, Kam Lun

doi:10.7573/dic.2021-8-6

Cited by 82 publications

(98 citation statements)

References 136 publications

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“…Benzoyl peroxide is a potent bactericidal mediator with a broad spectrum of activity due to its oxidizing activity [6]. In addition to having anti-inflammatory, keratolytic, and comedolytic properties, minor-to-temperate acne vulgaris is required to treat by the medication [7]. Physicians must balance the appropriate concentration, the vehicle base, and the risk of antagonistic effects, as greater concentrations are not usually effective.…”

Section: Benzoyl Peroxidementioning

confidence: 99%

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Endocrine Disorders and Hormonal Therapy for Adolescent Acne

Assawaruangsin¹

2022

ijcsrr

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Acne vulgaris is a worldwide disease which is mostly found in teenagers. This has a crucial impact on their life’s quality, particularly when endocrine disorders have been implicated. Current consideration regarding antibiotic stewardship, failing with antibiotic utilization, and the improvement of antibiotic-resistant Propionibacterium acnes, there are many treatment alternatives for pimple therapy have been acknowledged. A following analysis investigates hormonal treatments for the therapy of acne vulgaris.

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Section: Benzoyl Peroxidementioning

confidence: 99%

“…There is no concurrence regarding the relative beneficial effects of the topical retinoids presently available (tretinoin, adapalene, tazarotene, and isotretinoin). Tolerability may be affected by the carrier in which a retinoid is administered [5,7]. Adapalene was commonly more well-tolerated than all other retinoids studied.…”

Section: B Topical Retinoidsmentioning

confidence: 99%

Endocrine Disorders and Hormonal Therapy for Adolescent Acne

Assawaruangsin¹

2022

ijcsrr

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“…Acne vulgaris is the most common skin disease with a prevalence of acne ranging from 35% to close to 100% of adolescents having acne at some point [1][2][3]. Common treatments consisting of topically applied retinoids or benzoyl peroxide usually cause intolerance reactions, such as dryness of the skin, scaling, redness, irritation and even allergies [2]. Frequently used oral antibiotics may cause nausea, diarrhoea, disruption of the microbiome, photosensitivity, drug reactions and allergies [2].…”

Section: Introductionmentioning

confidence: 99%

“…Common treatments consisting of topically applied retinoids or benzoyl peroxide usually cause intolerance reactions, such as dryness of the skin, scaling, redness, irritation and even allergies [2]. Frequently used oral antibiotics may cause nausea, diarrhoea, disruption of the microbiome, photosensitivity, drug reactions and allergies [2]. Especially the prolonged use of oral or topical antibiotics leading to bacterial resistance is of major concern among dermatologists [4].…”

Section: Introductionmentioning

confidence: 99%

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A Prospective, Randomised, Controlled, Split-Face Clinical Trial to Assess the Safety and the Efficacy of Cold Atmospheric Plasma in the Treatment of Acne Vulgaris

et al. 2021

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The increase in antibiotic resistance requires effective non-antibiotic therapies for acne. Cold atmospheric plasma (CAP) inactivates bacteria and improves wound healing, but its effect on acne has not been investigated. The objective of this controlled split-face study was to assess safety and efficacy of CAP in moderate acne. One side of the face received 8–10 treatments with cold helium plasma within 4–6 weeks; follow-up was two and four weeks thereafter. Acne lesions were counted, followed by global acne severity ratings. Of the 34 patients included, 29 completed the study. No serious adverse events occurred. The two facial sides did not significantly differ in the number of inflammatory and non-inflammatory lesions. An interaction effect of number and type of treatment was found for inflammatory lesions. Lesion reduction after 10 treatments was significantly higher on the treated than on the untreated side. Percentage of patients reporting improved aesthetics was higher for the treated than for the untreated side after treatment completion (79% vs. 45%) and at the two- (72% vs. 45%) and four-week follow-up (79% vs. 52%). In conclusion, CAP was safe with excellent tolerability, showed moderate reduction in acne lesions and led to higher patient-based ratings of aesthetics than non-treatment.

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Prevalence, molecular characterization, and clinical features of human bocavirus in children under 5 years of age with acute gastroenteritis admitted to a specialized children's hospital in Iran: A cross‐sectional study

Kachooei,

Karbalaie Niya,

Khales

et al. 2023

Health Science Reports

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Background and AimsAlthough some reports have confirmed the role of human bocavirus (HBoV) in respiratory infections, the importance of this virus in causing acute gastroenteritis has not yet been proven. This study aimed to determine the molecular prevalence of HBoV in children under 5 years old with gastroenteritis and to compare the clinical symptoms of HBoV‐positive and ‐negative gastroenteritis cases.MethodsA total of 100 stool samples were collected from children with gastroenteritis hospitalized in a pediatric hospital in Tehran, Iran. Demographic and clinical data were collected from patients' medical records. Viral genomic DNA was extracted from stool samples and amplified using the PCR assay. Finally, sequencing was used to determine the genotype of HBoV.ResultsThe HBoV genome was detected in 14 samples (14%). The highest prevalence of HBoV was observed in the age range of 24–60 months (n = 5; 35.7%); However, no statistically significant relationship was observed between the prevalence of HBoV and age groups (p = 0.09). Nine (64.3%) and 5 (35.7%) HBoV‐positive cases were boys and girls, respectively (p = 0.45). Fever, vomiting, and heartache were seen in 5 (35.7%), 3 (21.4%), and 1 (7.1%) HBoV‐positive patients, respectively. Overall, no significant difference was observed in any of the investigated clinical manifestations between patients positive or negative for HBoV. Five HBoV‐positive samples were subjected to sequencing and all five sequenced samples were genotype 3.ConclusionHBoV infections can be considered a risk factor for causing at least a portion of acute gastroenteritis cases in children under 5 years of age.

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Dermatology: how to manage acne vulgaris

Cited by 82 publications

References 136 publications

Endocrine Disorders and Hormonal Therapy for Adolescent Acne

Endocrine Disorders and Hormonal Therapy for Adolescent Acne

A Prospective, Randomised, Controlled, Split-Face Clinical Trial to Assess the Safety and the Efficacy of Cold Atmospheric Plasma in the Treatment of Acne Vulgaris

Prevalence, molecular characterization, and clinical features of human bocavirus in children under 5 years of age with acute gastroenteritis admitted to a specialized children's hospital in Iran: A cross‐sectional study

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