Dermatologists’ Role in the Early Diagnosis of Psoriatic Arthritis: Expert Recommendations

Belinchón, I.; Salgado‐Boquete, Laura; López‐Ferrer, Anna; Ferrán, Marta; Coto‐Segura, Pablo; Rivera, R.; Vidal, David; Rodríguez, Lourdes; Cueva, Pablo de la; Queiró, Rubén

doi:10.1016/j.adengl.2020.10.025

Cited by 11 publications

(27 citation statements)

References 73 publications

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“…Currently, psoriasis is mainly diagnosed by skin computed tomography-(CT-) confocal laser scanning microscopy (CLSM), dermatoscopy examination, blood examination, skin biopsy, and trace element examination [12][13][14]. Due to the effectiveness and convenience of examination, skin CT examination has become the most widely used detection method.…”

Section: Introductionmentioning

confidence: 99%

Three-Dimensional Skin CT Based on Intelligent Algorithm in the Analysis of Skin Lesion Sites Features in Children with Psoriasis

Wang

Zheng

Ran

et al. 2022

Computational and Mathematical Methods in Medicine

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This research was to explore the application value of three-dimensional computed tomography (CT) based on artificial intelligent algorithm in analyzing the characteristics of skin lesions in children with psoriasis. In this study, 15 children with psoriasis were selected as the observation group, and 15 children with other skin diseases were selected as the control group. The CT images were optimized, and the feature selection was carried out based on artificial intelligent algorithm. Firstly, the results were compared with the results of simple skin three-dimensional CT to determine the effectiveness. Then, the two groups of three-dimensional skin CT image features of skin psoriasis-like hyperplasia, Munro microabscess, dermal papillary vascular dilation, and squamous epithelium based on intelligent algorithms were compared. After comparison, the detection rate of psoriasis-like hyperplasia, Munro microabscess, dermal papillary vascular dilation, and squamous epithelium in the observation group was higher than that in the control group, with significant difference and statistical significance ( P < 0.05 ). In addition, the sensitivity of psoriasis-like hyperplasia, Munro microabscess, dermal papilla vascular dilatation, and squamous epithelium in children with psoriasis was 80.0%, 86.7%, 80.0%, and 93.3%, respectively. The specificity of psoriasis-like hyperplasia, Munro microabscess, dermal papilla vascular dilatation, and squamous epithelium in children with psoriasis was 86.7%, 93.3%, 60.0%, and 73.3%, respectively. The results showed that Munro microabscess and psoriasis-like hyperplasia had high sensitivity and specificity in all diagnostic items, which could be used as important features of skin lesion sites in the diagnosis of psoriasis in children. The research provides a basis for the clinical diagnosis of psoriasis in children, which is worthy of clinical promotion.

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Section: Introductionmentioning

confidence: 99%

Three-Dimensional Skin CT Based on Intelligent Algorithm in the Analysis of Skin Lesion Sites Features in Children with Psoriasis

Wang

Zheng

Ran

et al. 2022

Computational and Mathematical Methods in Medicine

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“…However, the sensitivity and specificity of current screening methods of PsA remain relatively low. [2] Dermatology and rheumatology departments in China have begun to jointly participate in the online cooperation, aiming to find suitable screening tools for the early diagnosis of PsA. Early arthritis for psoriatic patients (EARP) is a simple and user-friendly screening tool, which is more sensitive than that of PASE and PEST.…”

mentioning

confidence: 99%

“…Notably, telemedicine is of great significance in the multidisciplinary management of psoriasis, especially in the current situation of COVID-19 epidemic. [2] Nowadays, the advantages of multidisciplinary treatment have become increasingly remarkable. PsA patients used to request for the treatment in the dermatology and rheumatology departments separately, and as a result, a coordination between specialists from each department and a thorough communication taking into consideration of multidisciplinary care is lacking, leading to a suboptimal care.…”

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confidence: 99%

A multidisciplinary team for the diagnosis and management of psoriatic arthritis

Zheng

2021

Chinese Medical Journal

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Psoriatic arthritis (PsA) is a special subtype of psoriasis, which severely influences the quality of life of the affected people. Clinical manifestations of PsA are diverse. In addition to skin lesions, PsA patients often have musculoskeletal symptoms, nail changes, and ophthalmological features that simultaneously or successively occur with the skin lesions. [1] Therefore, the diagnosis and treatment of PsA are challenging because of its various symptoms. In recent years, multidisciplinary management of PsA is gradually being valued, because early screening, diagnosis, and treatment can effectively control signs and symptoms of PsA, improve patients' quality of life, and slow down the disease progression to a larger extent. [1]

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“…IL-22 индуцирует остеопролиферацию в энтезисах и надкостнице через активацию STAT3 в остеобластах, вызывая образование новой костной ткани, проявляющееся формированием энтезофитов, шпор, анкилозов, сращением периферических суставов, а также образованием синдесмофитов в осевом скелете и изменениями в крестцово-подвздошных суставах [5,15,16 (артрит) и сухожилий сгибателей/разгибателей пальца (теносиновит), которое характеризует собой воспаление пальца -дактилит. Общие признаки различных клинических форм псориатического артрита -воспалительная боль, которая усиливается в покое и уменьшается при движениях, припухлость, ограничение подвижности суставов, возможно появление утренней скованности [17,18].…”

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“…Деструкция суставов у пациентов с псориатическим артритом может развиться всего через несколько лет после начала заболевания [22][23][24]. В ретроспективном исследовании показано, что задержка диагностики псориатического артрита всего на 6 месяцев связана с ухудшением долгосрочных рентгенологических и функциональных исходов [18,25], что определяет важное значение ранней диагностики псориатического артрита и выявления групп риска его развития, прежде всего в отношении больных псориазом.…”

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Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes

Kubanov

Карамова

Чикин

et al. 2021

Vestnik dermatologii i venerologii

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Psoriatic arthritis often develops in patients with psoriasis and can lead to joint deformity, stiffness, dysfunction, and disability. Psoriatic arthritis is a polygenic disease. and the issue of personalizing the prognosis of its development can only be resolved taking into account the variability of plenty genomic loci associated with the development of the disease. The personification of the prognosis of the disease can be solved taking into account the variability of the set of genomic loci with which its development is associated. The review examines genomic polymorphisms associated with the development of psoriatic arthritis not psoriasis, except of HLA polymorphisms. Genome regions containing polymorphisms, allelic variants of which are associated both with the development of psoriatic arthritis and reducing the likelihood of its occurrence, are described. It has been reported that the predisposition to the development of psoriatic arthritis in patients with psoriasis is determined by genes encoding proteins involved in inflammation and bone metabolism.

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Dermatologists’ Role in the Early Diagnosis of Psoriatic Arthritis: Expert Recommendations

Cited by 11 publications

References 73 publications

Three-Dimensional Skin CT Based on Intelligent Algorithm in the Analysis of Skin Lesion Sites Features in Children with Psoriasis

Three-Dimensional Skin CT Based on Intelligent Algorithm in the Analysis of Skin Lesion Sites Features in Children with Psoriasis

A multidisciplinary team for the diagnosis and management of psoriatic arthritis

Genetic markers for psoriatic arthritis in patients with psoriasis. Part I: non-HLA genes

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