Dermatological Problems

Vega‐López, F.; Ritchie, Sara

doi:10.1016/b978-0-7020-5101-2.00069-8

Cited by 4 publications

(3 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These natural antioxidants found in marine algae can be applied into skincare products for anti-aging, hence replace the use of the synthetic chemical hydroquinone, a skin-bleaching agent with harmful side effects especially to sensitive skin which may even cause ochronosis. 28 Anti-microbial compounds such as α-Kosin and phytosphingosine are found in both species. They are found to be able to treat bacteria-infected acne.…”

Section: Discussionmentioning

confidence: 99%

“…while 2‐fluoro palmitic acid is involved in the inhibition of sphingosine biosynthesis where sphingosine signals for cell apoptosis. These natural antioxidants found in marine algae can be applied into skincare products for anti‐aging, hence replace the use of the synthetic chemical hydroquinone, a skin‐bleaching agent with harmful side effects especially to sensitive skin which may even cause ochronosis 28 …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

LC–MS profiling‐based non‐targeted secondary metabolite screening for deciphering cosmeceutical potential of Malaysian algae

Lim

Yow

Gew

2023

J of Cosmetic Dermatology

View full text Add to dashboard Cite

BackgroundApplication of natural resources from the marine environment in the cosmeceutical industry is gaining great attention.AimThis study pursues to discover the cosmeceutical potential of two Malaysian algae, Sargassum sp. and Kappaphycus sp. by determining their antioxidant capacity and assessing the presence of their secondary metabolites with cosmeceutical potential using non‐targeted metabolite profiling.MethodsMetabolite profiling using Quadrupole Time‐of‐Flight (Q‐TOF) liquid chromatography‐mass spectrometry (LC–MS) in the Electrospray Ionization (ESI) mode resulted in 110 putative metabolites in Sargassum sp. and 47 putative metabolites in Kappaphycus sp. and were grouped according to their functions. To the best of our knowledge, the bioactive compounds of both algae have not been studied in any great detail. This is the first report to explore their cosmeceutical potential.ResultsSix antioxidants were detected in Sargassum sp., including fucoxanthin, (3S, 4R, 3'R)‐4‐Hydroxyalloxanthin, enzacamene N‐stearoyl valine, 2‐hydroxy‐hexadecanoic acid, and metalloporphyrins. Meanwhile, three antioxidants detected in Kappahycus sp., namely Tanacetol A, 2‐fluoro palmitic acid and idebenone metabolites. Three antioxidants are found in both algae species, namely, 3‐tert‐Butyl‐5‐methylcatechol, (−)‐isoamijiol, and (6S)‐dehydrovomifoliol. Anti‐inflammatory metabolites such as 5(R)‐HETE, protoverine, phytosphingosine, 4,5‐Leukotriene‐A4, and 5Z‐octadecenoic acid were also found in both species. Sargassum sp. possesses higher antioxidant capacity as compared to Kappahycus sp. which may be linked to its number of antioxidant compounds found through LC–MS.ConclusionsHence, our results conclude that Malaysian Sargassum sp. and Kappaphycus sp. are potential natural cosmeceutical ingredients as we aim to produce algae cosmeceutical products using native algae.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

LC–MS profiling‐based non‐targeted secondary metabolite screening for deciphering cosmeceutical potential of Malaysian algae

Lim

Yow

Gew

2023

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…Leishmaniasis comprises three protozoan parasitic diseases found in parts of the tropics, the subtropics and southern Europe and transmitted to humans by the bite of phlebotomine sand flies of the genus Phlebotomus or Lutzomya ( Vega-Lopez and Ritchie, 2014 ; CDC, 2020a ; WHO, 2022c ). Three main forms of leishmaniasis infect people: cutaneous, visceral and mucocutaneous ( WHO, 2022c ).…”

Section: Introductionmentioning

confidence: 99%