Dermatological Lesions of Cholesterol Embolization Syndrome and Kaposi Sarcoma Mimic Primary Systemic Vasculitis

Abstract

Primary systemic vasculitis can present with a wide spectrum of manifestations ranging from systemic non-specific features such as fever, malaise, arthralgia, and myalgia to specific organ damage. We describe two cases of cholesterol embolization syndrome and Kaposi sarcoma mimicking primary systemic vasculitis, both of which were characterized by features such as livedo reticularis, blue toe syndrome, a brown, purpuric skin rash, and positive p-ANCA associated with Kaposi sarcoma. Establishing the right diagnosis was challenging, and thus we aim in this study to highlight the possible ways to distinguish them from primary systemic vasculitis.
 Keywords: Dermatological lesions, Cholesterol embolization syndrome, Kaposi sarcoma, vasculitis mimic.

On the problem of differential diagnosis in the detection of antineutrophil cytoplasmic antibodies

“…Иммуносупрессивная терапия AAB иногда провоцирует ЗНО и в то же время химиотерапия у пациентов со ЗНО может привести к развитию ААВ [88,89]. AНЦA к ПР3 или МПO встречаются и при рецидивирующем полихондрите [90], а среди неревматических заболеванийпри муковисцидозе [91] и синдроме холестериновой атероэмболии [92], что может привести к диагностическим ошибкам.…”