“…This female predominance was obvious for all age groups except for patients aged between 41 and 60 years. This observation is in line with previous studies showing that female patients exhibit greater unease and concern with skin-related disorders [10, 15, 16]. …”
Section: Discussionsupporting
confidence: 82%
“…This percentage is in line with those reported by Gil Mateo et al [19] (86%), but slightly higher than that reported by Grillo et al [10] (57%).…”
Section: Discussionsupporting
confidence: 79%
“…Despite the broad range of the patient demographics and characteristics, ranging from neonates to elderly people, the average age of patients seeking evaluation was 45 years, a finding in line with previous reports [1, 10, 11, 15]. …”
Section: Discussionsupporting
confidence: 77%
“…Among the patients evaluated in our emergency consultation, 7.7% necessitated hospital admission, a percentage higher than that reported in the studies of Grillo et al [10] and of Bancalari-Díaz et al [15], in which hospital admission occurred in 2 and 1.9% of cases, respectively. It is conceivable that the presence in the same hospital of a dermatological inpatient ward facility make the admission of these patients easier.…”
Section: Discussioncontrasting
confidence: 48%
“…Furthermore, in southern Switzerland, most dermatological private practices are closed on Thursday afternoon, making access to specialized care more difficult. In apparent contrast to previous studies [5, 10, 15], Monday was the weekday with the smallest number of emergency visits. It is conceivable that this is related to the possibility to be examined either as emergency in our referral center during the weekend or in private practices of dermatology rapidly after the weekend.…”
Background/Aims: The spectrum of dermatological emergencies is broad. Only a few studies have assessed the profile of dermatological conditions resulting in an emergency visit in a referral hospital. We sought to assess the conditions prompting an urgent dermatological visit and to compare the diagnoses with those made during the regular scheduled encounters. Methods: We performed a cross-sectional study of all patients with a cutaneous problem attending our emergency consultation during a 7-month period. The study variables were gender, age, duration of symptoms, diagnosis, need for hospitalization and/or follow-up. We further evaluated patients attending scheduled visits to compare the demographic characteristics and diagnoses between the two groups. Results: Six hundred fifty-two consecutive patients with an urgent dermatological consultation were included. Three hundred sixty (55.2%) were women and 292 (44.8%) were men. Infectious diseases (32.8%) as well as various forms of eczema (24.8%) constituted the most frequent causes for an emergency visit. Approximately 40% of emergency visits took place more than 1 week after the development of the cutaneous manifestations. The most frequent disorders seen in the 1,738 control patients included benign melanocytic and nonmelanocytic tumors (27.2%) and malignant skin lesions (11.5%). Conclusions: Our study indicates that the dermatological diagnoses in the emergency visits significantly differ from those of the routinely scheduled appointments. In a significant portion of patients, the use of an emergency consultation was not justified. This study provides support to the idea that a specific training is required to manage dermatological emergencies and that efforts should be made to reduce unjustified emergency visit use.
“…This female predominance was obvious for all age groups except for patients aged between 41 and 60 years. This observation is in line with previous studies showing that female patients exhibit greater unease and concern with skin-related disorders [10, 15, 16]. …”
Section: Discussionsupporting
confidence: 82%
“…This percentage is in line with those reported by Gil Mateo et al [19] (86%), but slightly higher than that reported by Grillo et al [10] (57%).…”
Section: Discussionsupporting
confidence: 79%
“…Despite the broad range of the patient demographics and characteristics, ranging from neonates to elderly people, the average age of patients seeking evaluation was 45 years, a finding in line with previous reports [1, 10, 11, 15]. …”
Section: Discussionsupporting
confidence: 77%
“…Among the patients evaluated in our emergency consultation, 7.7% necessitated hospital admission, a percentage higher than that reported in the studies of Grillo et al [10] and of Bancalari-Díaz et al [15], in which hospital admission occurred in 2 and 1.9% of cases, respectively. It is conceivable that the presence in the same hospital of a dermatological inpatient ward facility make the admission of these patients easier.…”
Section: Discussioncontrasting
confidence: 48%
“…Furthermore, in southern Switzerland, most dermatological private practices are closed on Thursday afternoon, making access to specialized care more difficult. In apparent contrast to previous studies [5, 10, 15], Monday was the weekday with the smallest number of emergency visits. It is conceivable that this is related to the possibility to be examined either as emergency in our referral center during the weekend or in private practices of dermatology rapidly after the weekend.…”
Background/Aims: The spectrum of dermatological emergencies is broad. Only a few studies have assessed the profile of dermatological conditions resulting in an emergency visit in a referral hospital. We sought to assess the conditions prompting an urgent dermatological visit and to compare the diagnoses with those made during the regular scheduled encounters. Methods: We performed a cross-sectional study of all patients with a cutaneous problem attending our emergency consultation during a 7-month period. The study variables were gender, age, duration of symptoms, diagnosis, need for hospitalization and/or follow-up. We further evaluated patients attending scheduled visits to compare the demographic characteristics and diagnoses between the two groups. Results: Six hundred fifty-two consecutive patients with an urgent dermatological consultation were included. Three hundred sixty (55.2%) were women and 292 (44.8%) were men. Infectious diseases (32.8%) as well as various forms of eczema (24.8%) constituted the most frequent causes for an emergency visit. Approximately 40% of emergency visits took place more than 1 week after the development of the cutaneous manifestations. The most frequent disorders seen in the 1,738 control patients included benign melanocytic and nonmelanocytic tumors (27.2%) and malignant skin lesions (11.5%). Conclusions: Our study indicates that the dermatological diagnoses in the emergency visits significantly differ from those of the routinely scheduled appointments. In a significant portion of patients, the use of an emergency consultation was not justified. This study provides support to the idea that a specific training is required to manage dermatological emergencies and that efforts should be made to reduce unjustified emergency visit use.
that approximately 20 to 30 NMEs were approved each year from 2000 through 2013. Topical NMEs are developed at a much lower rate (0.9 NMEs per year). These findings are consistent with prior studies 5 illustrating the underrepresentation of all drugs developed for primarily dermatological uses. Dermatological illnesses are not often fatal and may be considered lower priority by policymakers. Priority designations are assigned by the US Food and Drug Administration to new drugs that represent significant improvements over existing options and command more resource investment and regulatory attention. Only 5 total topical applications and 1 topical NME were given the priority review designation compared with 45% of all pharmaceutical and biological NMEs from 2000 through 2009. 6 Beyond being considered lower priority, traditional metrics of blood and urine drug levels often do not apply to topical therapies. The lack of accepted surrogate end points may explain why the median approval time for topical medications is comparable with oral and intravenous therapies despite representing a lower systemic risk. Given these regulatory challenges, the low number of active companies with the necessary expertise to develop topical therapeutics likely contributes to the continued high cost and low availability of these drugs. Prior studies on medical innovation of devices, small molecules, and biotechnology suggest a multifaceted approach to spur future development. 7 Strategies most likely to succeed include continued research funding to study diseases that are likely to be responsive to topical therapeutics and increased collaboration between academic and industry professionals. In the short term, adoption of more surrogate end points reduces the regulatory burden and may encourage companies to invest more resources in this underserved area.
Background
Urticaria is a common condition presenting both as acute and chronic disease within primary care. To those without specialist training it is poorly understood from the points of view of diagnosis and management. It causes a considerable disease burden to sufferers with marked impact on quality of life.
Purpose of this review
The recent publication of the EAACI/GA²LEN/EuroGuiDerm/APAAACI Guideline for the Definition, Classification, Diagnosis and Management of Urticaria guideline prompted us to take this excellent resource and re‐configure its findings and recommendations to a non‐specialist audience with particular reference to the needs of the primary care team.
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