Dermatolgical Complications of B.C.G. Vaccinatton.

Dostrovsky, A.; Sagher, F.

doi:10.1111/j.1365-2133.1963.tb13547.x

Cited by 43 publications

(15 citation statements)

References 6 publications

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“…Unter anderem sind wie beim vorliegenden Fall Ulzerationen beschrieben worden, z. B. infolge bakterieller Superinfektion, Kratzen, zu tiefer, d. h. subkutaner Injektion [4] oder Injektion einer zu großen Impfdosis [3], sowie Lupus-vulgaris-artige Reaktionen [8] und Keloide. Neben einer Vergröße-rung der regionalen Lymphknoten sind eitrig-einschmelzende, z. T. fistulierende Lymphadenitiden in 0,5-5% der Impfungen bekannt [13].…”

Section: Diskussionunclassified

BCG-Ulkus

Fritz

2002

Der Hautarzt

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Following BCG vaccination, local or systemic complications may occur. A 19-year-old female patient with negative tuberculin skin test developed a blister evolving over two weeks into an ulcer in a vaccination site on the left hip. Ulcerations following BCG vaccination are rare and show a tendency to chronicity. The treatment recommendations are controversial and range from non-specific topical treatment to systemic tuberculostatic therapy. In this case, the ulcer cleared rapidly after topical treatment with INH powder.

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Section: Diskussionunclassified

BCG-Ulkus

Fritz

2002

Der Hautarzt

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“…These skin tuberculosis lesions induced by B.C.G. vaccination develop more quickly, are more benign, and heal more easily than those of ordinary cutaneous tuberculosis (1). Clinically, the skin lesions in our patient did not fit into any of the preceding categories of cutaneous tuberculosis because of their unusual morphology and distribution.…”

Section: Case Reportmentioning

confidence: 88%

“…vaccination (1). These included scrofuloderma-like lesions, excessive specific lymphadenitis, papular tuberculid and lichen scrofulosorum like lesions, lichen nitidus lesions, and excessive ulceration at the vaccination site (1).…”

Section: Introductionmentioning

confidence: 99%

An Unusual Form of Skin Tuberculosis Following B.C.G. Vaccination

Lee

Hann

Chun

et al. 1994

The Journal of Dermatology

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A 25-year-old female has had brown to erythematous telangiectatic patches and grouped papules on her face, neck, arm, and trunk since childhood following B.C.G. vaccination. Histopathologically, the lesions consisted of hyperkeratosis, slight acanthosis, tuberculoid granulomas with some Langerhans type giant cells in the mid-dermis. Although various forms of cutaneous tuberculosis after B.C.G. vaccination have been reported, it was difficult for us to assign the patient's skin lesion to any specific disease entity. Remission of her cutaneous lesions occurred clinically and histopathologically after treatment with isoniazid and rifampin.

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“…Although enlargement of the draining lymph node is the expected result of vaccination and is not considered a complication, the breakdown of lymph nodes certainly is a complication. [9][10][11][12] The incidence of lupus vulgaris after BCG vaccination is very rare, estimated to be approximately 5 per million. 4,9 The reported time of onset of lupus vulgaris after BCG vaccine immunization could be as early as 1 month and as late as 4 years.…”

Section: Discussionmentioning

confidence: 99%