Dermatitis Venenata Caused by the Manzanillo Tree

Manchineel keratoconjunctivitis.

“…The mean period to complete resolution of epithelial damage was 3-75 days (range [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Two of our patients had stromal involvement: in one (patient 9), there was superficial stromal infiltrate in the acute phase (Fig 6) which disappeared in 3 weeks with return of visual acuity to 6/4.…”

“…"6 Duke-Elder also points out that some Euphorbiciae are responsible for a violent iridocyclitis with hypopyon (Tithymalus cyparissias and Euphorbia antiguorum), but Manchineel had not been reported to do so.' 5 Schaeffer et al'7 described the isolation of 2-hydro-4, 6-dimethoxy-acetophenone and a carotenoid substance from Manchineel leaves.…”

Contact Dermatitis Caused by the ‘Manzanillo’ <i>(Rhus striata) </i>Tree

“…The IHppomane mancinella L. (family Euphorbiaceac) is one of the poi sonous 'manzanillo' varieties with skin irritating properties which grows in tropical low lands near the seashore (3,6). Some sixty eases of Hippomane mancinella L. dermatitis were reported by Satui-Sky (7) and Satulsky and W irts (8) in Panamá; according to their description, it differs clinically from Rhus striata dermatitis. Furthermore, the geographical location where the dermatitis ap pears might be of diagnostic help, since Rhus striata grows only at 800 m and higher above the sea level.…”