Dermatitis Nodularis Necrotica

Arteriolitis (Vasculitis) “Allergica” Cutis (Superficialis). A New Dermatological Concept

“…A pparently Latapi's view th at in this phenomenon other micro-organisms than the leprosy bacillus play an im portant role, is supported by this observation (see aetio-pathogenesis of a.a.c.!). Finally Binkley [1] came to the conclusion, that a poorly understood dermatosis as derm atitis nodularis necroticans represented a form of cutaneous allergic vasculitis. Orbaneja and Pujol made a similar observation and w rote: " It is quite possible th a t in future derm atitis nodularis necroticans should have to he considered as " a more ex tensive" variant of the papular-necrotic type of R uiter's allergic arteriolitis" .…”

Pathergic Granulomatosis

“…One of the earliest of these illnesses to be described was lethal midline granulomatosis.1 Soon after came dermatitis nodularis necrotica. [2][3][4] Dermatitis nodularis necrotica presents distinctive clinical features which, at first, forced one to regard it as unrelated to midline granuloma and other chronic dermonecrotic diseases; now I consider it a pathergic disease. Polyarteritis nodosa 5 belongs here, as does Wegener's granulomatosis 6 (pathergic granulomatosis 7) with all its designations and eponyms.…”