2011
DOI: 10.4103/0378-6323.74986
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Dermatitis neglecta

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Cited by 26 publications
(31 citation statements)
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“…[4,9] Other findings with special stains include increased melanin content in the compact hyperkeratotic and basal areas of the epidermis (Fontana-Masson), [1,3] scattered keratin globules throughout stratum corneum (Toluidine blue) [1,3,9] and occasional yeast cells indicative of Pityrosporum (Periodic Acid Schiff). [3,9,10] The precise mechanism of TFFD remains obscure. Existing data does not support a familial predominance or genetic susceptibility.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…[4,9] Other findings with special stains include increased melanin content in the compact hyperkeratotic and basal areas of the epidermis (Fontana-Masson), [1,3] scattered keratin globules throughout stratum corneum (Toluidine blue) [1,3,9] and occasional yeast cells indicative of Pityrosporum (Periodic Acid Schiff). [3,9,10] The precise mechanism of TFFD remains obscure. Existing data does not support a familial predominance or genetic susceptibility.…”
Section: Discussionmentioning
confidence: 99%
“…[10][11][12] TFFD is distinguished from DN arbitrarily by presence of adequate hygiene, absence of cornflake-like brownish scales and successful eradication of pigmentation with isopropyl alcohol in the former and effective clearance of lesions with soap and water in the latter. [1,3,4,[7][8][9][10][11] However, isopropyl alcohol is operative in both disorders. [1,9] Histologically, DN is similar to TFFD, except for the absence of whorled hyperkeratosis in DN.…”
Section: Discussionmentioning
confidence: 99%
“…3 Pode afetar todas as faixas etárias e ambos os sexos. 4,5 Frequentemente é uma afecção subdiagnosticada 3,6 e eventos estressantes anteriores ao início do quadro podem atuar como fatores desencadeantes. 6 Higiene inadequada gera acúmulo progressivo de restos celulares, sebo, suor e outras substâncias exógenas (medicamentos tópi-cos, "lixo") resultando clinicamente em áreas de hiperpigmentação plana e até placas verrucosas com escamas aderentes.…”
Section: Discussionunclassified
“…Esta afecção deve fazer parte dos diagnósticos diferenciais de lesões hiperpigmentadas localizadas, principalmente em paciente com quadros crônicos caracterizados por dor e imobilidade. 6 Entre os diagnósticos diferenciais citamos recidiva tumoral, nevo verrucoso, acantose nigricante, papilomatose confluente e reticulada de Gougerot e Carteaud, ictioses, pitiríase versicolor e hiperpigmentação pós-inflamatória. 3 Higiene simples com álcool ou água e sabão pode definir os casos de dúvida diagnóstica.…”
Section: Discussionunclassified
“…2 Pathological examination of the plaques ethyl or isopropyl alcohol-although salicylic acidbased exfoliants or other keratolytic agents are sometimes recommended to accelerate normalisation of the skin. 7 Unfortunately, topical corticosteroids, antimycotics and retinoids are sometimes prescribed inappropriately for cases of TFFD. 8 Physicians should therefore be aware of this entity to avoid performing unnecessary skin biopsies and to ensure that they prescribe appropriate treatment.…”
Section: Commentmentioning
confidence: 99%