Dermal-fat graft for anophthalmic socket in children enucleated for retinoblastoma

Bosch-Canto, Vanessa; Cruz, Carlos Fabián Martínez; Ordaz-Fávila, Juan Carlos

doi:10.1016/j.oftale.2017.06.008

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…According to previous research, DFG has multiple indications, such as congenital anophthalmia [ 14 , 15 ], contracted anophthalmic socket (if there is enough vascularized tissue) [ 16 , 17 ], enucleation per primam or per secundam [ 13 ], chronic anophthalmic socket pain [ 7 , 18 ], as primary and secondary orbital implants for both adults [ 19 ] and children [ 20 ], anophthalmic socket in children enucleated for RB [ 21 ], early implant exposure [ 22 ], superior sulcus reconstruction [ 23 , 24 ], fornix reconstruction [ 25 ], and eyelid malposition [ 15 ]. Smith et al proposed that the advantage of the DFG lies in its ability to replace the orbital volume, while, at the same time, maintaining the fornix and conjunctiva [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

A Sandwich-Like Oral Mucosa Graft–Conjunctiva In Situ–Dermis-Fat Graft for Reconstruction of the Anophthalmic Socket with Ocular Infection History

et al. 2022

Ophthalmol Ther

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Introduction A novel technique of using a sandwich-like structure, namely, an oral mucosa graft (OMG)–conjunctiva in situ–dermis-fat graft (DFG) (OMG-C-DFG), to reconstruct a contracted and low-capacity anophthalmic socket for a patient with ocular infection history was evaluated. Methods This was retrospective case study of four patients (cases) who underwent anophthalmic socket reconstruction surgery in which the OMG-C-DFG technique was applied. The procedures were performed in the Department of Ophthalmology at the Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine (Shanghai, China). Postoperative cosmetic appearance, graft outcome, the ability to wear an ocular prosthesis, and postoperative complications were evaluated. Results The median (± standard deviation) age of patients was 41.5 ± 22.1 (range 10–60) years. All patients suffered from contracted and low-capacity anophthalmic sockets. Three patients had a history of orbital implant infection and one patient had a history of enucleation due to exogenous endophthalmitis after globe rupture. The DFG and OMG were harvested from the abdominal region and lower lip, respectively. All four patients achieved a good postoperative appearance, with dermal surfaces appearing pink and smooth, the orbital areas showing good fullness, the ocular prosthesis showing good wearability, and no narrowing of the sockets. There was no lipid secretion, fat lysate outflow, or infection in the graft bed. There were only small amounts of scars and no infection of the donor site. Conclusion The sandwich-like structure can be effectively used to reconstruct the contracted and low-capacity anophthalmic socket with a history of orbital infection in one stage.

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Section: Discussionmentioning

confidence: 99%

A Sandwich-Like Oral Mucosa Graft–Conjunctiva In Situ–Dermis-Fat Graft for Reconstruction of the Anophthalmic Socket with Ocular Infection History

et al. 2022

Ophthalmol Ther

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“…Porous/integrated implants have been chosen in approximately 70% of enucleations performed in developed countries and 30% in underdeveloped nations, with no worldwide consensus for children with retinoblastoma [19]. In countries where orbital implants are not readily available, dermal-fat grafts continue as a viable option for prompt anophthalmic socket reconstruction [24, 25].…”

Section: Introductionmentioning

confidence: 99%

Orbital Complications and Cost Analysis of Enucleation by Myoconjunctival versus Conventional Techniques for Retinoblastoma

Lando¹,

Mallipatna²,

Kletke³

et al. 2023

Ocul Oncol Pathol

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Introduction: To compare complication rates and hospital costs of myoconjunctival versus conventional enucleation techniques in retinoblastoma. Methods: This retrospective cohort and cost analysis reviewed patients with retinoblastoma treated by primary or secondary enucleation between 2003-2021 and a minimum 6-month follow-up. Cases were reviewed for three post-surgical complications: chronic conjunctivitis, implant exposure/extrusion, and cellulitis. Cases were excluded if surgery was performed elsewhere or documentation was incomplete. Treatment costs were estimated based on two sample cases billed in 2021 that manifested the studied complications and represented each of the two surgical techniques. Univariate and multivariate analyses were applied to compare complication rates and treatment costs. Results: Included were 180 eyes (179 patients); 140 were excluded. Patients were median age 18.9 (0-104.4) months at diagnosis, the majority male (94, 52%), with unilateral (115, 64%) Group D or E (163, 91%) eyes. Enucleation was performed by conventional techniques in 107 eyes (59%) and by myoconjunctival approach in 73 (41%). Orbital complications occurred in 61 eyes (34%) during a median follow-up of 7.9 (0.5-33.7) years, more frequently in the conventional technique group (p=0.014). The myoconjunctival technique had significantly lower costs for implant price (p<0.001) and estimated treatment cost, including complication management (p<0.001). Conclusion: Enucleation by myoconjunctival technique showed significantly less complication burden and treatment cost, indicating advantages over conventional approaches. Study limitations include the retrospective nature, confounders' complexity, and follow-up time variations.

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Dermal-fat graft for anophthalmic socket in children enucleated for retinoblastoma

Cited by 2 publications

References 8 publications

A Sandwich-Like Oral Mucosa Graft–Conjunctiva In Situ–Dermis-Fat Graft for Reconstruction of the Anophthalmic Socket with Ocular Infection History

A Sandwich-Like Oral Mucosa Graft–Conjunctiva In Situ–Dermis-Fat Graft for Reconstruction of the Anophthalmic Socket with Ocular Infection History

Orbital Complications and Cost Analysis of Enucleation by Myoconjunctival versus Conventional Techniques for Retinoblastoma

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