Dermal Configurations in the Diagnosis of the Down Syndrome: An Attempt at a Simplified Scoring Method

Dermatoglyphs of Chinese children and Down's syndrome.

“…The strict definition of a transverse palmar crease used in this work makes comparison with most other series difficult, but our Chinese controls had a higher frequency than found in European populations, though the patient groups were similar (Beckman et al, 1962;Davies and Smallpeice, 1963;Beckman et al, 1965). This observation is in agreement with an extensive comparative study by Van Der Wiel (1953).…”

Gene deletion and duplication effects on phenotype and gamma globulin levels.

“…Bilateral simian creases are rare in normal individuals. They are seen in Down's syndrome (Beckman, Gustavson, and Norring, 1965), D trisomy (Uchida, Patau, and Smith, 1962), E trisomy (Gibson, Uchida, and Lewis, 1963), and a diversity of congenital defects. Two (II.…”

“…7) of our three cases of partial trisomy had a distally placed axial triradius. Distal axial triradii are seen in Down's syndrome (Beckman et al, 1965), D and E trisomy (Uchida et al, 1962), Turner's syndrome (Holt and Lindsten, 1964), and congenital heart disease (Sinchez Cascos, 1964).…”

Beckman’s Scoring Method and Racial Admixture in Normal Individuals

“…The possibility of using dermatoglyphics as a feasible screening tool for diseases gained its major applicability with the development of scoring methods as a diagnostic aid in Down's syndrome [Turpin and Lejeune, 1953;Walker, 1957;1958;Beckman et al. 1965], but no scoring method has been developed to estimate, even grossly, the degree of racial admixture.…”