Deriving life‐course residential histories in brain bank cohorts: A feasibility study
Eleanna M. Melcher,
Leigha Vilen,
Aly Pfaff
et al.
Abstract:INTRODUCTIONThe exposome is theorized to interact with biological mechanisms to influence risk for Alzheimer's disease but is not well‐integrated into existing Alzheimer's Disease Research Center (ADRC) brain bank data collection.METHODSWe apply public data tracing, an iterative, dual abstraction and validation process rooted in rigorous historic archival methods, to develop life‐course residential histories for 1254 ADRC decedents.RESULTSThe median percentage of the life course with an address is 78.1% (IQR 2… Show more
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