Derivation and Validation of a CT Scan Scoring System for Discriminating Malignant From Benign Pleural Effusions

Porcel, José M.; Pardina, Marina; Bielsa, Silvia; González, A.; Light, Richard W.

doi:10.1378/chest.14-0013

Cited by 70 publications

(66 citation statements)

References 14 publications

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“…Porcel et al evaluated CT scan scoring system which included the presence of pleural lesion >1 cm, liver metastases, lung mass or lung nodule more than 1 cm, the absence of loculations, pericardial effusion and non-enlarged cardiac silhouette. CT score of ≥7 was found to predict malignancy with an 88% sensitivity and 94% specificity (20) Additional findings which are …”

Section: Computed Tomography (Ct)mentioning

confidence: 79%

Diagnosis and management of malignant pleural effusions: state of the art in 2017

Desai

Lee

2017

J. Thorac. Dis.

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Malignant pleural effusion (MPE) is a known complication of both thoracic and extra thoracic malignancies. The presence of MPE regardless of the primary site translates into advanced stage disease.Diagnosis and management of MPE with the goals of palliation and improving quality of life poses a challenge for chest physicians. Recently, multiple studies have made attempts to answer questions regarding optimal management in various clinical scenarios. We will review the current evidence and available options for the management of MPE.

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Section: Computed Tomography (Ct)mentioning

confidence: 79%

Diagnosis and management of malignant pleural effusions: state of the art in 2017

Desai

Lee

2017

J. Thorac. Dis.

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“…In a retrospective series involving 370 patients who had both a CT scan and a pleural biopsy for undiagnosed effusions, the sensitivity and specificity of the CT scan for malignant disease were 68% and 78%, respectively. 26 Although a prediction score has been developed to differentiate benign from malignant effusions, 27 it was derived and validated in a single centre and requires further study.…”

Section: What Should Be Done If the Initial Evaluation Is Nondiagnostic?mentioning

confidence: 99%

Evaluation of the patient with pleural effusion

Beaudoin

Gonzalez

2018

CMAJ

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“…The scoring was done based on these variables. 12 Tumour marker study has been projected as one of the investigations to be done in pleural fluid to make a diagnosis of malignancy. This is as yet not available in most of the centres.…”

Section: Resultsmentioning

confidence: 99%

Predictors of Malignancy in Lymphocytic Pleural Effusions

Nair¹,

Ghosh²,

Sankaran³

2017

jemds

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BACKGROUNDCommonest causes of exudative pleural effusions are synpneumonic, tuberculous and malignant. Synpneumonic effusions are usually neutrophilic in fluid cytology, while the other two are lymphocyte predominant. Elevated pleural fluid adenosine deaminase can suggest a tuberculous aetiology in clinically suspected cases. Malignant effusions need a fluid cytology positive for malignant cells to make a diagnosis. If not yielding, invasive biopsies need to be done. This study was undertaken to find out a group of variables, which can predict malignancy in lymphocytic pleural effusions. Aim-To identify the best predictor of malignancy in lymphocytic pleural effusions. Settings and Design-This was a cross-sectional study done in the Pulmonary Medicine Department, GMC, Trivandrum during the year 2000.

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Derivation and Validation of a CT Scan Scoring System for Discriminating Malignant From Benign Pleural Effusions

Cited by 70 publications

References 14 publications

Diagnosis and management of malignant pleural effusions: state of the art in 2017

Diagnosis and management of malignant pleural effusions: state of the art in 2017

Evaluation of the patient with pleural effusion

Predictors of Malignancy in Lymphocytic Pleural Effusions

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