Der Wert der MR-Mammographie in der Differentialdiagnostik von non-puerperaler Mastitis und inflammatorischem Mammakarzinom bei 1,5 Tesla

Tomczak, R; Rieber, A.; Zeitler, H.; Rilinger, N.; Brambs, H.-J.

doi:10.1055/s-2007-1015730

Cited by 9 publications

(2 citation statements)

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“…Moreover, in several studies, mammary ductal ectasia has been found to be responsible for 5–25% of all symptomatic breast conditions [ 4 , 5 ]. The clinical presentations of PDM are not specific and are easily confused with breast carcinoma in imaging manifestations [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Periductal Mastitis: An Inflammatory Disease Related to Bacterial Infection and Consequent Immune Responses?

Liu

Zhou

Wang

et al. 2017

Mediators of Inflammation

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Periductal mastitis (PDM) is a prolonged inflammatory disease, but the cause of PDM is poorly understood. In the present case control study, 87 PDM and 87 healthy controls were enrolled and the results were evaluated to identify the significant risk factors for PDM. To investigate the roles of bacterial infection and critical cytokines expression, 16S rRNA gene sequencing and bacterial culturing were conducted. We also measured the levels of interferon-γ, interleukin-12A, and interleukin-17A by semiquantitative immunohistochemistry method. In a multivariable logistic regression model, we identified overweight/obesity and late onset of menarche as independent risk factors for PDM. In contrast, age of first birth >27 years had a protective effect. With 16S rRNA gene sequencing, we confirmed bacterial infections were found in all PDM patients, but none of the control patients was positive on the gene expression of 16S rRNA. Our results also demonstrated significant increases of the IFN-γ and IL-12A expression in PDM, but there was no difference in IL-17A expression in these two groups. Taken together, this study suggests that reproductive factors and overweight/obesity are possible predisposing risk factors for PDM. Bacterial infection and the increased expression of some proinflammatory cytokines are associated with the pathogenesis of this disease.

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Section: Introductionmentioning

confidence: 99%

Periductal Mastitis: An Inflammatory Disease Related to Bacterial Infection and Consequent Immune Responses?

Liu

Zhou

Wang

et al. 2017

Mediators of Inflammation

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“…Auch bei Vorliegen inflammatorischer Mammaveränderungen ± insbesondere zur Differenzierung zwischen einer Mastitis und einem inflammatorischen Mammacarcinom ± ist die MRM wenig hilfreich [34]. Auch bei Vorliegen inflammatorischer Mammaveränderungen ± insbesondere zur Differenzierung zwischen einer Mastitis und einem inflammatorischen Mammacarcinom ± ist die MRM wenig hilfreich [34].…”

Section: Indikationen Für Die Mrmunclassified

Präoperative MR-Mammographie beim Mammacarcinom Einfluß auf die operative Behandlung aus chirurgischer Sicht

Gatzemeier

Liersch

Stylianou

et al. 1999

Chirurg

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Not only for the differential diagnosis of discrepant findings between X-ray mammography and ultrasound, but especially for the diagnosis of multifocal or multicentric lesions, MRM seems to be the method of choice. Consequently, MRM plays an important role in planning the operative procedure in breast cancer patients, especially in the context of breast preservation. To ensure optimal use of this new diagnostic tool high technical standards, proper expertise on the part of the examining radiologist, and effective cooperation among the involved disciplines (radiology, pathology, surgery) must be guaranteed.

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Inflammatory carcinoma of the breast: Characteristic findings of MR imaging

Yasumura¹,

Ogawa

Ishikawa

et al. 1997

Breast Cancer

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Inflammatory breast carcinoma (IBC) Shows a unique clinical appearance and has an extremely poor prognosis. Although immediate intensive therapy has been proposed, diagnosis of this disease tends to be delayed as its clinical features can be confused with acute mastitis. The conventional imaging modalities including mammography and ultrasonography are of limited value in the diagnosis of IBC, as it is difficult to delineate specific findings of the swollen dense breast. Recently, magnetic resonance (MR) imaging has been widely applied to breast diseases. One of the excellent features of this modality is its diagnostic ability in dense breasts. However, few trials to evaluate the capability of this new modality for IBC have been documented. In recent years, we found that a characteristic feature in 5 cases of IBC was a strong signal on T2-weighted images (T2WI) of MR imaging at the retromammary and subcutaneous area. Pathological features of the retromammary area showed marked interstitial edema and focal lymphatic involvement by tumor cells. These characteristic images obtained by MR imaging may be suggestive of inflammatroy breast carcinoma. Furthermore, subtracted dynamic MR imaging indicated the site of the tumor. Therefore, the application of MR imaging for swollen breasts would assist in the immediate diagnosis of IBC and would contribute to appropriate and timely therapy.

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Der Wert der MR-Mammographie in der Differentialdiagnostik von non-puerperaler Mastitis und inflammatorischem Mammakarzinom bei 1,5 Tesla

Abstract: MRM proved useful in the follow-up of treated mastitis to demonstrate the success of antibiotic treatment of mastitis and to diagnose a histologically unconfirmed inflammatory carcinoma by means of a different follow-up.

Cited by 9 publications

References 0 publications

Periductal Mastitis: An Inflammatory Disease Related to Bacterial Infection and Consequent Immune Responses?

Periductal Mastitis: An Inflammatory Disease Related to Bacterial Infection and Consequent Immune Responses?

Präoperative MR-Mammographie beim Mammacarcinom Einfluß auf die operative Behandlung aus chirurgischer Sicht

Inflammatory carcinoma of the breast: Characteristic findings of MR imaging

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