Der Stoffwechsel von Verbindungen mit Dreifachbindung. VII. Verteilung und Abbau der 9‐Octadecinsäure bei Ratten, ein Beitrag zur α‐Oxydation der C‐Kette

Abstract

SummaryOctadec-9-ynoic acid (stearolic acid) fed to rats leads to the metabolic excretion of six dicarboxylic acids with retained triple bond. The main metabolic steps are m-, p-, and presumably a-oxidation. Feeding of ''C-stearolic acid proves that the a-oxidative step involves the methyl end of the original acid. It could further be shown that this acid is incorporated partially in the body lipids. To a substantial degree it is totally oxidized and expired as l4C-CO,.