Der Einfluß der Phosphorversorgung auf die intestinale Absorption von Phosphor bei wachsenden Schweinen

Vemmer, Herward

doi:10.1111/j.1439-0396.1982.tb01251.x

Cited by 12 publications

(2 citation statements)

References 3 publications

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“…It may be argued that the apparent digestibility of P of the P sources is biased by the faecal endogenous excretion. However, according to Vemmer (1982) there is no great difference in the amount of endogenous P excreted in diets with 3 to 6 g total P kg '. On the other hand it is not very likely that there is a marked influence of source of inorganic feed phosphate used in the diet on the amount of endogenous P excreted.…”

Section: Discussionmentioning

confidence: 98%

A comparison of different techniques to assess the biological availability of feed phosphates in pig feeding.

Dellaert¹,

Peet²,

Jongbloed³

et al. 1990

NJAS

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Piglets from about 6 weeks old were fed on basal diets with P 0, 0.6, 1.2 or 1.8 g/kg, 0, 1.2 or 2.2 g/kg, and 0 or 2.0 g/kg in experiments 1, 2 and 3, respectively. Blood factors did not show a significant response to P intake. Plasma alkaline phosphatase activity was not linearly related to P intake, while regressing the inorganic P content to the quantity of supplemented P resulted in a low fitness of the model (Rsuperscript 2 = 53%). Results from bone fat-free DM, concentration of ash in fat-free DM, amount of ash, concentration of P in ash and bone breaking strength were better (Rsuperscript 2 = 45 to 94%). There were slight differences in the results using tibia, femur or third and fourth metatarsals. However, the highest degree of fit was found using the apparent digestibility of P as the dependent variable (Rsuperscript 2 = 96 to 100%). After relating the criteria to the retention of P, again the apparent P digestibility was the most accurate factor to determine the biological availability of P. Basing the nutritional value of feed phosphates on digestibility of P, significant differences were shown between form and origin of feed phosphate. The values within a type of feed phosphate showed a high repeatability. (Abstract retrieved from CAB Abstracts by CABI’s permission)

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Section: Discussionmentioning

confidence: 98%

A comparison of different techniques to assess the biological availability of feed phosphates in pig feeding.

Dellaert¹,

Peet²,

Jongbloed³

et al. 1990

NJAS

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“…Separate effects of calcium on parameters such as FGF23, described in genetically modified mice [78], were not expected in the own trial. It is known from practical feeding as well as preceding trials, that a nutritional supply with calcium in this magnitude does not lead to hypercalcemia in cats and dogs [7,24,70,79] nor to increased FGF23 concentrations in case of excessive calcium supply from 'organic' sources like meat and bone meal [24,70]. Furthermore, the addition of calcium carbonate caused a slight but biologically probably irrelevant increase in serum calcium concentrations with all values within the reference range.…”

Section: Discussionmentioning

confidence: 96%

The Phosphate Additives Phosphoric Acid and Sodium Phosphate Lead to Hyperphosphatemia as well as Increased FGF23 and Renal Phosphate Excretion in Healthy Cats

2023

J Urol Ren Dis

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Chronic Kidney Disease (CKD) is an increasingly frequent disease in geriatric cats, representing the leading cause of death in this species. Reports about the increasing prevalence of CKD exist also in human medicine. The intake of nutrients, notably phosphorus, can affect renal health. Dietary supply with phosphate can influence concentrations of phosphate and factors of the phosphate homeostasis in blood and urine, possibly causing adverse health effects. Investigating nutritional factors involved in the cause and aggravation of kidney damage in more detail is of high importance not only for feline health. The cat is already successfully used as model for various human diseases which highlights its potential role as translational model for phosphate toxicity in humans. Effects of the food additives H 3 PO 4 and NaH 2 PO 4 on phosphorus homeostasis were investigated in comparison to a control diet. Adding these highly available phosphate additives to the diet of healthy cats for 28 days caused a significant increase in serum phosphate, calcium, and FGF23 as well as in renal phosphorus excretion. Consequently, the use of both phosphate additives in food processing needs to be critically re-evaluated due to the high availability of these sources and therefore their potential adverse health effects. With up to 80 % prevalence, Chronic Kidney Disease (CKD) is one of the most common chronic diseases in geriatric cats [1,2], and represents the leading cause of death in this species [3]. Reports of the increasing prevalence of CKD in the last decades also exist in human medicine [4]. It has been shown in various species, including humans and cats, that the supply of nutrients, notably phosphorus, can affect renal health [5][6][7]. To investigate nutritional factors involved in cause and aggravation of kidney damage in more detail is therefore of high importance not only for feline health. The fact that the cat has been successfully used as a model for human diseases in several studies [8][9][10][11][12] supports its potential role as translational model for human medicine.

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Comparative evaluation of the efficacy of cereal and microbial phytases in growing pigs fed diets with marginal phosphorus supply

et al. 2002

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Two experiments with a total of 76 growing pigs (average initial body weight 16.6 kg) were conducted to compare the efficacy of cereal phytases (wheat and rye) and supplemented microbial phytase (Natuphos 1 ). Using the slope ratio technique, the dose-response relationship between five levels of phytase (0, 50, 100, 150 and 200 U kg À1 ) and the apparent absorption of phosphorus (P) within each source of phytase was calculated. Graded phytase levels in the diets were obtained by adding increasing amounts of microbial phytase or phytase-containing wheat (Exp 1) or rye (Exp 2) to phytase-inactivated basal diets at the expense of phytase-inactivated wheat (Exp 1) or rye (Exp 2). Except for wheat phytase, addition of phytase to the basal diets increased (P < 0.05) apparent P absorption, with microbial phytase being more efficient (P < 0.05) than cereal phytase. There were no significant differences in apparent P absorption between the wheat-or rye-based diets when either microbial or cereal phytases were supplemented from 0 to 200 U kg À1 . It could be derived from the results of this study, by means of regression analysis, that the efficacy of cereal phytases was 40% compared to microbial phytase.

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Der Einfluß der Phosphorversorgung auf die intestinale Absorption von Phosphor bei wachsenden Schweinen

Cited by 12 publications

References 3 publications

A comparison of different techniques to assess the biological availability of feed phosphates in pig feeding.

A comparison of different techniques to assess the biological availability of feed phosphates in pig feeding.

The Phosphate Additives Phosphoric Acid and Sodium Phosphate Lead to Hyperphosphatemia as well as Increased FGF23 and Renal Phosphate Excretion in Healthy Cats

Comparative evaluation of the efficacy of cereal and microbial phytases in growing pigs fed diets with marginal phosphorus supply

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