“…In bacteriological studies, these results were confirmed by the observation [15] of a much greater efficacy of caprylic acid against 'Pyococcus aureus' at pH 4 than at pH 5. Along the same lines, Rockl et al [20,21] found that "the water soluble constituents of the horny layer" as part of a so-called preliminary overall model will kill Staphylococcus aureus and "Staphylococcus albus" at pH 5, though not at pH 7 and 8. It would also appear that the pH of the skin environment can affect not only microbial counts as such, but also the enzymatic activity of the micro-organisms.…”