Der Darm

Patzelt, Viktor

doi:10.1007/978-3-662-36275-4_1

Cited by 14 publications

(12 citation statements)

References 456 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the nodule associated epithelium is heavily infiltrated with lymphocytes from the underlying lymph nodules (PATZELT, 1936;SHIMIZU and ANDREW, 1967;ABE and ITO, 1977;SCHMEDTJE,1980). Therefore, the intraepithelial spaces represent a contact area of lymphocytes with transported antigens.…”

mentioning

confidence: 99%

Intercellular spaces in the lymph nodule associated epithelium of the rabbit Peyer's patch and appendix.

Ogawa

Miyoshi

1985

Arch. Histol. Jap., Arch. Histol. Jpn

View full text Add to dashboard Cite

Summary. Intercellular spaces in the epithelium of the rabbit Peyer's patch and appendix were examined by scanning and transmission electron microscopy to elucidate their threedimensional structure and their relationship to the reticular spaces in the underlying lymph nodule.Two types of intercellular spaces were distinguished: regularly arranged tubular channels and irregularly winding tunnels. The tubular channels were observed around normal enterocytes on the villi or internodular folds and apical portions of nodule domes. The channel spaces were lined with a successive arrangement of belt-like intercrestal surfaces of prismatic enterocytes and variously sized processes on the crests. The processes adjoining opposed crests formed a ladder-like structure or pectinate septa between neighboring channels.The irregularly winding tunnels were formed among processes of irregularly shaped cells corresponding to FAE cells (BOCKMAN and COOPER, 1973) or M cells (OWEN and JONES, 1974) in the nodule associated epithelium. In the appendix, the tunnels were frequently organized into two-storey spaces, the adlumenal and basal spaces, which were incompletely separated by cytoplasmic processes. These tunnels continued by pores in the basement membrane to the reticular spaces in the underlying lymph nodules. Furthermore, the tunnels and the basement membrane pores constantly contained single or grouped free cells or their processes.The findings in the present study suggest that the tubular channels are intraepithelial compartments for the absorption of nutrients and fluid, and the irregular tunnels are an intraepithelial network of spaces for the housing of lymphoid cells coming from the underlying lymph nodule. The Peyer's patch and appendix are important constituents of the gut associated lymphoid tissue. In both organs, the lumenal portions of the lymph nodules bulge into the intestinal lumen and closely associate with the overlying epithelium.The nodule or follicle associated epithelium (FAE) is thought to play a mediating role in conveying immunological information from the intestinal lumen to the underlying lymphatic tissue (BOCKMAN et al., 1983). For this mediation function, specialized cells have been proposed, which are morphologically distinguishable from common enterocytes.

show abstract

mentioning

confidence: 99%

Intercellular spaces in the lymph nodule associated epithelium of the rabbit Peyer's patch and appendix.

Ogawa

Miyoshi

1985

Arch. Histol. Jap., Arch. Histol. Jpn

View full text Add to dashboard Cite

show abstract

“…Various configurations of the Golgi apparatus have been traditionally studied by osmium impregnation (Patzelt 1936). We also impregnated the mouse descending colon and found the round cage-like structures in the lower part of the crypt and cup-shaped structures in the upper part of the crypt.…”

Section: Discussionmentioning

confidence: 96%

The Golgi apparatus of goblet cells in the mouse descending colon: three-dimensional visualization using a confocal laser scanning microscope

Kataoka

Suzaki

Komura

2001

Histochem Cell Biol

View full text Add to dashboard Cite

The three-dimensional structure of the Golgi apparatus was studied in goblet cells in lectin-stained sections of the mouse descending colon by using a confocal laser scanning microscope. In the lower part of the crypt, the Golgi apparatus formed a dome- or globe-like structure in the supranuclear region. The wall of the dome had some holes, one of which usually faced toward the nucleus and others toward the apical cytoplasm. Mucous granules seemed to be initially released into the interior of the dome and transported toward the apical cytoplasm through the holes. In the upper part of the crypt, on the other hand, the Golgi apparatus formed a cup- or funnel-like structure with a larger opening toward the cell apex and a smaller opening toward the nucleus. A large mass of mucous granules occupied the inside of the cup to the apical cytoplasm. It is thought that the accumulation of mucous granules enlarges holes at the ceiling of the dome to form a large opening, which makes the configuration of the Golgi apparatus cup-shaped.

show abstract

“…11) (FARQUHAR and PALACE, 1963). These two attachment devices completely encircle each cell as described as a feature of the terminal bar by earlier light microscopists (see PATZELT, 1936). Apart from the terminal bar, another attachment apparatus often can be seen.…”

Section: Structural Specialization Of the Absorptive Surfacementioning

confidence: 92%

“…2), which are tiny adhesions between adjacent epithelial cells beneath the striated border. These devices firmly attach one cell to another and seal the intercellular clefts (see PATZELT, 1936). Later, electron microscopy has disclosed the fine structure of the terminal bars (FARQUHAR and PALACE, 1963) and their functional implications will be discussed later.…”

Section: Structural Specialization Of the Absorptive Surfacementioning

confidence: 99%