Depth-Resolved Full-Field Measurement of Corneal Deformation by Optical Coherence Tomography and Digital Volume Correlation

Fu, Jiawei; Haghighi-Abayneh, M.; Pierron, Fabrice; Ruiz, Pablo D.

doi:10.1007/s11340-016-0165-y

Cited by 32 publications

(20 citation statements)

References 61 publications

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“…In terms of 3D imaging characteristics, OCT has some specificities. First, standard optics may require refraction corrections to be applied for curved objects [72]. This is important for a genuine rendering of the microstructure.…”

Section: Optical Coherence Tomographymentioning

confidence: 99%

“…Significant progress was made in the design of new testing setups and more importantly on the understanding of various degradation mechanisms that could only be revealed thanks to observations in the bulk of materials [56,26]. Depending on the imaging modality and the studied material, the loading device had to be adapted to the experimental environment [14,164,72].…”

Section: Introductionmentioning

confidence: 99%

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Digital Volume Correlation: Review of Progress and Challenges

et al. 2018

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3D imaging has become popular for analyzing material microstructures. When time lapse series of 3D pictures are acquired during a single experiment, it is possible to measure displacement fields via digital volume correlation (DVC), thereby leading to 4D results. Such ForewordThe present paper aims at reviewing the major developments in Digital Volume Correlation (DVC) over the past ten years. It follows the first review on DVC that was published in 2008 by its pioneer [11]. In the latter, the interested reader will find all the general principles associated with what is now called local DVC. They will not be recalled hereafter. In such approaches the region of interest is subdivided into small subvolumes that are independently registered. In addition to its wider use with local approaches, DVC has been extended to global approaches in which the displacement field is defined in a dense way over the region of interest. Kinematic bases using finite element discretizations have been selected. To further add mechanical content, elastic regularization has been introduced. Last, integrated approaches use kinematic fields that are constructed from finite element simulations with chosen constitutive equations. The material parameters (and/or boundary conditions) then become the quantities of interest.These various implementations assume different degrees of integration of mechanical knowledge about the analyzed experiment. First and foremost, DVC can be considered as a stand-alone technique, which has seen its field of applications grow over the last ten years. In this case the measured displacement fields and post-processed strain fields are reported. With the introduction of finite element based DVC, the measured displacement field is continuous. It is also a standalone technique. However, given the fact that it shares common kinematic bases with numerical simulations, it can be easily combined with the latter. One route is to require local satisfaction of equilibrium via mechanical regularization. Another route is to fully merge DVC analyses and numerical simulations via integrated approaches. Different examples will illustrate how these various integration steps can be tailored and what are the current challenges associated with various approaches.

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Section: Optical Coherence Tomographymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Digital Volume Correlation: Review of Progress and Challenges

et al. 2018

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“…In this context, methods similar to those used for mapping strains in compressional OCT‐based elastography look especially promising. For example, recent OCT visualizations of corneal deformation were reported using digital image correlation (DIC) principles. However, techniques for displacement/strain mapping based on DIC (that are successfully applied to photographic image processing ) run into significant difficulties in OCT, because they are corrupted by strong deformation‐induced speckle decorrelation .…”

Section: Introductionmentioning

confidence: 99%

Optical coherence elastography for strain dynamics measurements in laser correction of cornea shape

Zaitsev

Matveyev

Matveev

et al. 2017

Journal of Biophotonics

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We describe the use of elastographic processing in phase-sensitive optical coherence tomography (OCT) for visualizing dynamics of strain and tissue-shape changes during laser-induced photothermal corneal reshaping, for applications in the emerging field of non-destructive and non-ablative (non-LASIK) laser vision correction. The proposed phase-processing approach based on fairly sparse data acquisition enabled rapid data processing and near-real-time visualization of dynamic strains. The approach avoids conventional phase unwrapping, yet allows for mapping strains even for significantly supra-wavelength inter-frame displacements of scatterers accompanied by multiple phase-wrapping. These developments bode well for real-time feedback systems for controlling the dynamics of corneal deformation with 10-100 ms temporal resolution, and for suitably long-term monitoring of resultant reshaping of the cornea. In ex-vivo experiments with excised rabbit eyes, we demonstrate temporal plastification of cornea that allows shape changes relevant for vision-correction applications without affecting its transparency. We demonstrate OCT's ability to detect achieving of threshold temperatures required for tissue plastification and simultaneously characterize transient and cumulative strain distributions, surface displacements, and scattering tissue properties. Comparison with previously used methods for studying laser-induced reshaping of cartilaginous tissues and numerical simulations is performed.

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“…Although the effective strain measurement range is limited to 0.6%, for larger strain an incremental strain measurement can be used. The minimum value of correlation coefficient for effective measurement is taken as 0.4 in this study, which is lower than the values calculated by the normalized cross correlation (NCC) criterion . If NCC is used to calculate the correlation coefficients shown in Figure A, the value will be greater than 0.9 for strains applied up to 1.6%.…”

Section: Discussionmentioning

confidence: 91%

Three‐dimensional static optical coherence elastography based on inverse compositional Gauss‐Newton digital volume correlation

Meng

Cheng

Hui

et al. 2019

Journal of Biophotonics

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The three‐dimensional (3D) mechanical properties characterization of tissue is essential for physiological and pathological studies, as biological tissue is mostly heterogeneous and anisotropic. A digital volume correlation (DVC)‐based 3D optical coherence elastography (OCE) method is developed to measure the 3D displacement and strain tensors. The DVC algorithm includes a zero‐mean normalized cross‐correlation criterion‐based coarse search regime, an inverse compositional Gauss‐Newton fine search algorithm and a local ternary quadratic polynomial fitting strain calculation method. A 3D optical coherence tomography (OCT) scanning protocol is proposed through theoretical analysis and experimental verification. Measurement errors of the DVC‐based 3D OCE method are evaluated to be less than 2.0 μm for displacements and 0.30% for strains by rigid body motion experiments. The 3D displacements and strains of a phantom and a specimen of chicken breast tissue under compression are measured. Results of the phantom show a good agreement with theoretical analysis and tensile testing. The strains of the chicken breast tissue indicate anisotropic biomechanical properties. This study provides an effective method for 3D biomechanical property studies of soft tissue and improves the development of 3D OCE techniques.

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Depth-Resolved Full-Field Measurement of Corneal Deformation by Optical Coherence Tomography and Digital Volume Correlation

Cited by 32 publications

References 61 publications

Digital Volume Correlation: Review of Progress and Challenges

Digital Volume Correlation: Review of Progress and Challenges

Optical coherence elastography for strain dynamics measurements in laser correction of cornea shape

Three‐dimensional static optical coherence elastography based on inverse compositional Gauss‐Newton digital volume correlation

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