Depressive symptoms prior to and following insulin initiation in patients with type 2 diabetes mellitus: Prevalence, risk factors and effect on physician resource utilisation

Dzida, Grzegorz; Karnieli, Eddy; Svendsen, Anne Louise; Sølje, K S; Hermanns, Norbert

doi:10.1016/j.pcd.2015.01.002

Cited by 9 publications

(8 citation statements)

References 50 publications

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“…Similarly, in the literature major depressive disorder rate in patients with diabetic complications were found higher than in patients without diabetic complications. [5232526]…”

Section: Discussionmentioning

confidence: 99%

Evaluation of quality of life and depression levels in individuals with Type 2 diabetes

Altinok

Marakoğlu

Kargın

2016

J Family Med Prim Care

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Introduction:Improving the quality of life in diabetic individuals is known to reduce morbidity and mortality. We aimed to investigate the quality of life and depression symptomatology situations and the related factors in patients with Type 2 diabetes mellitus (DM) in this study.Materials and Methods:In this study, 440 adult patients with Type 2 DM and under treatment admitted to Selcuk University Family Medicine Outpatient Diabetes Education Clinic were included in the study. A questionnaire containing sociodemographic characteristics of the participants, the Short Form 36 (SF-36) quality of life questionnaire was applied with Beck depression inventory face to face interviews.Results:Mean scores of females in all SF-36 subscales were statistically significantly lower than those of male patients. Physical function, physical role limitations, general health, social function, emotional role limitations, and mental health mean scores of the patients with 1–10 years duration of diabetes were found statistically significantly higher than those with 20 years and over duration of diabetes. Physical function, physical role limitations, pain, general health, and social function mean scores in patients using oral antidiabetic drug (OAD) was statistically significantly higher compared to patients using insulin + OAD. The average physical function scores of the patients with no complications were statistically significantly higher than those with two and more complications.Conclusion:Quality of life and depression symptomatology are worse in females, the elderly, the overweight, people with lower level of education, in the widowed or divorced, homemakers, those with low incomes, those with longer duration of diabetes, patients using insulin, and those with two or more complications. There are many medical and sociodemographic factors affecting the quality of life and depressive symptomatology in the individuals with diabetes, so both health care workers and patients should pay the necessary attention to this issue.

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“…Similarly, in the literature major depressive disorder rate in patients with diabetic complications were found higher than in patients without diabetic complications. [5232526]…”

Section: Discussionmentioning

confidence: 99%

Evaluation of quality of life and depression levels in individuals with Type 2 diabetes

Altinok

Marakoğlu

Kargın

2016

J Family Med Prim Care

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“…In addition to beliefs about medication, emotional well‐being, including depressive symptomology and diabetes‐related distress, is associated with optimal medication‐taking behaviours. For example, depression is associated with suboptimal medication‐taking among people with type 2 diabetes prescribed OAD medications and/or insulin , and diabetes‐related distress is associated with more negative insulin perceptions . Elsewhere, a longitudinal study concluded that severity of depressive symptoms was associated with required time and number of visits with healthcare professionals for training to self‐inject, self‐adjust and manage other aspects of insulin delivery .…”

Section: What Have the Past 25 Years Of Research Told Us?mentioning

confidence: 99%

“…For example, depression is associated with suboptimal medication‐taking among people with type 2 diabetes prescribed OAD medications and/or insulin , and diabetes‐related distress is associated with more negative insulin perceptions . Elsewhere, a longitudinal study concluded that severity of depressive symptoms was associated with required time and number of visits with healthcare professionals for training to self‐inject, self‐adjust and manage other aspects of insulin delivery . Thus, those reporting impaired emotional well‐being may be more vulnerable to delayed medication uptake, and be more likely to have suboptimal medication‐taking behaviours.…”

Section: What Have the Past 25 Years Of Research Told Us?mentioning

confidence: 99%

Psychosocial aspects and contributions of behavioural science to medication‐taking for adults with type 2 diabetes

et al. 2019

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The aim of this narrative review was to determine the contribution of behavioural and psychosocial research to the field of medication‐taking for adults with type 2 diabetes over the past 25 years. We review the behavioural and psychosocial literature relevant to adults with type 2 diabetes who are treated with oral antidiabetes agents, glucagon‐like peptide‐1 receptor agonists and insulin. Delayed uptake of, omission of and non‐persistence with medications are significant problems among adults with type 2 diabetes. At each stage of the course of diabetes, during which medication to lower blood glucose is initiated or intensified, ~50% of people take less medication than prescribed. Research aimed at increasing optimal medication‐taking behaviour has targeted ‘forgetfulness’, developing interventions which aid medication‐taking, such as reminder devices, with limited success. In parallel, investigation of beliefs about medication has provided insights into the perceived necessity of and concerns about medication and how these inform medication‐taking decisions. Guidance is available for health professionals to facilitate shared decision‐making, particularly with insulin therapy; however, interventions addressing medication beliefs are limited. Optimal medication‐taking behaviour is essential to prevent hyperglycaemia in adults with type 2 diabetes. Evidence from the past 25 years has demonstrated the association between medication beliefs and medication‐taking behaviour. Health professionals need to address medication concerns, and establish and demonstrate the utility of diabetes medication with the individual within the clinical consultation. There are interventions that may assist diabetes health professionals in the shared decision‐making process, but further development and more robust evaluation of these tools and techniques is required.

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“…In contrast to these results, other studies have found that higher depressive symptoms predict increases in HbA1c and more difficulty with self-management over time. 31,55 However one previous study examining the effect of pre-intervention depressive symptoms for people with diabetes in a lifestyle-focused weight loss intervention showed that participants at all levels of baseline depressive symptoms lost similar amounts of weight during the intervention. 56 Two similar studies of participants in DSME/S interventions showed that changes in depressive symptoms over the course of an intervention were not correlated with changes in HbA1c over the course of the intervention.…”

Section: Discussionmentioning

confidence: 99%

Do pre-existing diabetes social support or depressive symptoms influence the effectiveness of a diabetes management intervention?

Rosland

Kieffer

Spencer

et al. 2015

Patient Education and Counseling

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Objective Examine influences of diabetes-specific social support (D-SS) and depressive symptoms on glycemic control over time, among adults randomized to a diabetes self-management education and support (DSME/S) intervention or usual care. Methods Data were from 108 African-American and Latino participants in a six-month intervention trial. Multivariable linear regression models assessed associations between baseline D-SS from family and friends and depressive symptoms with changes in HbA1c. We then examined whether baseline D-SS or depression moderated intervention-associated effects on HbA1c. Results Higher baseline D-SS was associated with larger improvements in HbA1c (adjusted ΔHbA1c -0.39% for each +1-point D-SS, p=0.02), independent of intervention-associated HbA1c decreases. Baseline depressive symptoms had no significant association with subsequent HbA1c change. Neither D-SS nor depression moderated intervention-associated effects on HbA1c. Conclusions and Practice Implications Diabetes self-management education and support programs have potential to improve glycemic control for participants starting with varying levels of social support and depressive symptoms. Participants starting with more support for diabetes management from family and friends improved HbA1c significantly more over six months than those with less support, independent of additional significant DSME/S intervention-associated HbA1c improvements. Social support from family and friends may improve glycemic control in ways additive to DSME/S.

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Depressive symptoms prior to and following insulin initiation in patients with type 2 diabetes mellitus: Prevalence, risk factors and effect on physician resource utilisation

Abstract: Depressive symptoms are common with type 2 diabetes and associated with increased healthcare utilisation, reinforcing the need for holistic interdisciplinary management approaches.

Cited by 9 publications

References 50 publications

Evaluation of quality of life and depression levels in individuals with Type 2 diabetes

Evaluation of quality of life and depression levels in individuals with Type 2 diabetes

Psychosocial aspects and contributions of behavioural science to medication‐taking for adults with type 2 diabetes

Do pre-existing diabetes social support or depressive symptoms influence the effectiveness of a diabetes management intervention?

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