Depressive symptoms in patients with obstructive sleep apnea/hypopnea syndrome

Castro, Jorge Rey de; Rosales-Mayor, Edmundo

doi:10.1007/s11325-012-0731-1

Cited by 20 publications

(13 citation statements)

References 30 publications

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“…In an Iranian sleep clinic population of 685 OSA patients, Asghari et al [29] reported that BDI depressive symptoms were present in 70 % of women versus 49 % of men. A Peruvian study conducted with 244 OSA patients reported that 18 % of patients had BDI-defined depression [30]. In a recent Australian study conducted among patients referred to a sleep clinic due to snoring, 28 % had physician-diagnosed depression and 32 % had HADS scores and 25 % had MINI scores suggesting depression [31].…”

Section: Prevalence Among Patients In Sleep Clinicsmentioning

confidence: 99%

Comorbid depression in obstructive sleep apnea: an under-recognized association

et al. 2015

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Section: Prevalence Among Patients In Sleep Clinicsmentioning

confidence: 99%

Comorbid depression in obstructive sleep apnea: an under-recognized association

et al. 2015

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“…As mentioned, several studies have already investigated the association between MDD and coexisting OSA (18,(24)(25)(26)(27). However, a few studies have examined if coexisting OSA could lead to treatment-resistance in MDD or a bidirectional association could be anticipated (i.e.…”

Section: Introductionmentioning

confidence: 99%

Higher Risk for Obstructive Sleep Apnea in Chronic Treatment-Resistant Depression

Khazaie

Alavi-Mehr

Younesi

et al. 2018

Iran J Psychiatry Behav Sci

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Objectives: Studies have reported a higher risk for obstructive sleep apnea (OSA) in major depressive disorder (MDD). However, the risk of OSA in patients with chronic treatment-resistant depressive symptoms is not well documented worldwide. Hence, the current study assessed the risk of OSA and associated factors in patients with chronic treatment resistant depression (cTRD). Methods: The study recruited 140 Iranian patients with cTRD. All patients completed the Berlin questionnaire, which evaluates the risk of OSA. Additionally, demographic data and history of cardiovascular or metabolic diseases were collected. Pearson's Chi-square test, Fisher's exact test, and independent T-test were used to assess group differences, when appropriate. Results: The study found that 89 of 140 cTRD patients (64%) were at high risk for OSA. Group comparison between cTRD patients (high vs. low risk for OSA) demonstrated that at high risk OSA-cTRD patients had an elevated rate of hypertension, diabetes mellitus, and obesity. Also, age, duration of depression, and duration of treatment were significantly higher in cTRD patients with higher risk compared to those with lower risk for OSA. Conclusions:The results suggest that a noticeable number of patients with cTRD are at high risk for OSA, which is higher than the reported magnitude in the general population. Moreover, hypertension, diabetes mellitus, and obesity are associated with a higher risk for OSA. Also, age, treatment duration, and depression duration could be considered as possible comorbid factors for OSA in patients with cTRD.

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“…Obstructive sleep apnoea (OSA) is the most common sleep disorder worldwide, affecting 2%–6% of the adult population, increasing up to 15%–26% in those aged 70–100 years old. 1 OSA is characterised by repetitive complete (apnoea) and partial (hypopnoea) obstruction of the upper airway during sleep, which decreases arterial oxygen saturation. 2 Daytime functioning may be impaired due to loss of energy, depressed mood, irritability and concentration difficulties, which are core symptoms of affective disorders.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, sleepiness itself is one of the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) criteria of depressive disorder and also overlaps with the criterion of fatigue or loss of energy. 1 These diagnostic complexities may delay proper diagnosis of OSA in patients with depression. The aim of this case report is to increase awareness of the possibility of OSA in patients with depression.…”

Section: Introductionmentioning

confidence: 99%

When a patient with depression is feeling sleepy, be aware of sleep apnoea

Wiersema¹,

Zelst

Voshaar

2018

BMJ Case Reports

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A 67-year-old man was referred to an outpatient clinic of geriatric psychiatry because of persistent symptoms of depression and anxiety, accompanied by sleepiness. The latter had been evaluated multiple times in the general practice over several years; each time it was considered to be a symptom of depression. After referral, the patient was diagnosed with severe obstructive sleep apnoea (OSA), comorbid to a depressive and anxiety disorder. Retrospectively, we conclude that affective symptoms accompanying OSA and sleepiness were wrongfully interpreted as depression, but after having led to problems at work, they have triggered psychiatric comorbidity. Treatment of OSA in addition to the psychiatric disorders resulted in a full recovery over time. The delayed diagnosis of OSA has certainly diminished the patient’s quality of life and might have precipitated the depressive disorder. Moreover, OSA poses patients at an increased risk of cardiovascular disease, hypertension, stroke and traffic accidents.

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Depressive symptoms in patients with obstructive sleep apnea/hypopnea syndrome

Abstract: No association was found between depressive symptoms and OSAH.

Cited by 20 publications

References 30 publications

Comorbid depression in obstructive sleep apnea: an under-recognized association

Comorbid depression in obstructive sleep apnea: an under-recognized association

Higher Risk for Obstructive Sleep Apnea in Chronic Treatment-Resistant Depression

When a patient with depression is feeling sleepy, be aware of sleep apnoea

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