Depressive symptoms in midlife: the role of reproductive stage

Almeida, Osvaldo P.; Marsh, Kylie; Flicker, Leon; Hickey, Martha; Sim, Moira; Ford, Andrew H.

doi:10.1097/gme.0000000000000598

Cited by 22 publications

(16 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Having persistent and/or troublesome VMS and sleep problems can make women feel stressed and irritable, which in turn can exacerbate menopausal symptoms. An estimated 9–10% of women report an increase in psychological symptoms, including depressed mood and/or anxiety, during the menopause transition (Almeida et al, 2016 ; Mishra & Kuh, 2012 ), which tends to be relatively transient, and is associated with troublesome VMS, current stress, low self‐esteem, and hormone fluctuations (Arnot, Emmott, & Mace, 2021 ; Campbell, Dennerstein, Finch, & Szoeke, 2017 ; Willi, Süss, Grub, & Ehlert, 2021 ). Longer duration of VMS has been linked with higher levels of perceived stress (Avis et al, 2015 ); acute psychological stress has been shown to provoke VMS (Swartzman, Edelberg, & Kemmann, 1990 ); there is also some evidence of altered physiological stress responsivity in women with VMS (Nathan et al, 2020 ).…”

Section: Figurementioning

confidence: 99%

Is cognitive behaviour therapy an effective option for women who have troublesome menopausal symptoms?

Hunter

Chilcot

2021

British J Health Psychol

View full text Add to dashboard Cite

Hot flushes and night sweats, or vasomotor symptoms (VMS), are the main physical symptoms attributable to the menopause, affecting approximately 80% of women, and the main reason that women seek treatment (Guthrie, Dennerstein, Taffe, & Donnelly, 2003). Temperature regulation is affected by reducing levels of oestrogen and is associated with changes in central nervous system neurotransmitters, causing heat, sweating, redness and sometimes shivering, with varied duration and severity (Archer et al., 2011). An estimated 25-30% of women report problematic VMS (i.e., flushes that impact on daily life). Interestingly, it is the extent to which the VMS are perceived as problematic, rather than their frequency, that is associated with quality of life (QOL) and help-seeking behaviours Hunter, Nuttall, & Fenlon, 2019), which consequently is the main outcome that we seek to change.There are bi-directional relationships between VMS and mood, and both can lead to sleep problems and reduced QOL (Maki et al., 2019). Having persistent and/or troublesome VMS and sleep problems can make women feel stressed and irritable, which in turn can exacerbate menopausal symptoms. An estimated 9-10% of women report an increase in psychological symptoms, including depressed mood and/or anxiety, during the menopause transition (

show abstract

Section: Figurementioning

confidence: 99%

Is cognitive behaviour therapy an effective option for women who have troublesome menopausal symptoms?

Hunter

Chilcot

2021

British J Health Psychol

View full text Add to dashboard Cite

show abstract

“…Women with a history of depression or anxiety were more prone to develop mood symptoms during menopause. 3,9,12,15,17,22 A history of anxiety also increased the risk of development of depressive symptoms during menopause. 3,9 The prospective long-term Zurich study 12 demonstrated that neuroticism (a personality trait disposition to negative mood and anxiety) at age 30 significantly predicted increased prevalence of major depression and anxiety disorders during menopause.…”

Section: Synthesis Of Resultsmentioning

confidence: 99%

“…Pimenta et al 8 showed that psychological symptoms were significantly elevated in peri-menopausal women compared to matched pre-menopausal women. Almeida et al 9 reported that reproductive status did not affect the prevalence of MDD, but when contrasted with pre-menopause, the peri-menopausal phase was associated with an elevated risk of developing depressive symptoms.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Does menopause elevate the risk for developing depression and anxiety? Results from a systematic review

Alblooshi

Taylor

Gill

2023

Australas Psychiatry

View full text Add to dashboard Cite

Objective To determine whether menopause elevates the risk for developing diagnostic depression and anxiety. Menopause-associated vasomotor symptoms such as insomnia and hot flushes are well recognized, but no systematic review of the psychological consequences of menopause has been undertaken. Menopause can be a time of social change for women, confounding any correlation. Methods Using PRISMA methodology, we conducted a systematic review of all published (in English) original data examining a relationship between menopause and depression and anxiety. We ranked the quality of all included studies using Grading of Recommendations, Assessment, Development and Evaluation (GRADE) criteria. Results Twenty-two selected studies were summarized and compared, being eight cross-sectional surveys; one retrospective cohort, and 13 prospective cohort studies. Depression and anxiety are common during menopause and the post-menopause, with vasomotor symptoms and a prior history of major depression elevating risk of menopausal associated depression. Psychosocial factors also may increase risk of depression during menopause. Conclusions Menopause increases vulnerability to depression and anxiety, perhaps via estrogen fluctuations affecting serotonin and GABA. Underlying neuroticism and contemporaneous adverse life events are also risk factors for menopausal decompensation with depression.

show abstract

“…Although depressive symptoms during the menopausal transition cannot be attributed directly to the reproductive status [12], women with a depressive episode earlier in life show a higher risk for the recurrence of depressive symptoms during the perimenopause [13][14][15]. However, even women who have been mentally healthy throughout their life may experience negative mood states through to depression during this phase [10,11,16,17].…”

Section: Introductionmentioning

confidence: 99%

Psychological resilience during the perimenopause

Süss

Ehlert

2020

Maturitas

View full text Add to dashboard Cite

A B S T R A C TThe menopausal transition is a critical phase for psychological disorders such as depression and anxiety, with prevalence rates of depression ranging up to 20% during the menopause. Nevertheless, the majority of women cope adequately with this reproductive transition phase and thus appear to be resilient. We assert that a variety of psychological factors influence the menopausal transition and result in an individual state on a continuum from successful adjustment to maladjustment. The purpose of this review is to offer a conceptual framework of resilience factors during the menopausal transition and to reveal which dimensions of resilience have already been verified for a healthy menopausal transition.We searched the databases PubMed and PsycINFO for studies investigating resilience factors during the menopausal transition which influence psychological and physical adjustment or maladjustment. A total of 23 articles were included.Altogether, we identified 15 different resilience factors, assessed with 23 different questionnaires. These factors can be grouped into six categories: core resilience, spirituality, control, optimism, emotion and selfrelated resilience. They are associated with a better adjustment to menopausal symptoms, milder physical symptoms, a better quality of and satisfaction with life, better well-being, less perceived stress and fewer depressive symptoms compared with women with lower levels of the respective resilience factors.Our conceptual framework includes resilience factors which have already been verified by empirical data. Further research is needed to determine whether these resilience factors can be assigned to a common factor and to incorporate biological resilience markers. already accompanied by various family, social and professional changes

show abstract

Depressive symptoms in midlife: the role of reproductive stage

Abstract: The slight, but not significant, excess of depressive symptoms during MT and early postmenopause cannot be attributed to a direct effect of reproductive status.

Cited by 22 publications

References 22 publications

Is cognitive behaviour therapy an effective option for women who have troublesome menopausal symptoms?

Is cognitive behaviour therapy an effective option for women who have troublesome menopausal symptoms?

Does menopause elevate the risk for developing depression and anxiety? Results from a systematic review

Psychological resilience during the perimenopause

Contact Info

Product

Resources

About