Depressive symptoms and risk of uterine leiomyomata

Wise, Lauren A.; Li, Se; Palmer, Julie R.; Rosenberg, Lynn

doi:10.1016/j.ajog.2014.12.012

Cited by 14 publications

(9 citation statements)

References 63 publications

(73 reference statements)

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“…Total scores range from 0 to 60. Persons scoring 16 or above are generally classified as having a level of depressive symptoms compatible with a diagnosis of clinical depression (32).…”

Section: Covariatesmentioning

confidence: 99%

Attendance at Religious Services, Prayer, Religious Coping, and Religious/Spiritual Identity as Predictors of All-Cause Mortality in the Black Women's Health Study

VanderWeele¹,

Yu²,

Cozier³

et al. 2017

American Journal of Epidemiology

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Previous longitudinal studies have consistently shown an association between attendance at religious services and lower all-cause mortality, but the literature on associations between other measures of religion and spirituality (R/S) and mortality is limited. We followed 36,613 respondents from the Black Women's Health Study from 2005 through December 31, 2013 to assess the associations between R/S and incident all-cause mortality using proportional hazards models. After control for numerous demographic and health covariates, together with other R/S variables, attending religious services several times per week was associated with a substantially lower mortality rate ratio (mortality rate ratio = 0.64, 95% confidence interval: 0.51, 0.80) relative to never attending services. Engaging in prayer several times per day was not associated with mortality after control for demographic and health covariates, but the association trended towards a higher mortality rate ratio when control was made for other R/S variables (for >2 times/day vs. weekly or less, mortality rate ratio = 1.28, 95% confidence interval: 0.99, 1.67; P-trend < 0.01). Religious coping and self-identification as a very religious/spiritual person were associated with lower mortality when adjustment was made only for age, but the association was attenuated when control was made for demographic and health covariates and was almost entirely eliminated when control was made for other R/S variables. The results indicate that service attendance was the strongest R/S predictor of mortality in this cohort.

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“…Total scores range from 0 to 60. Persons scoring 16 or above are generally classified as having a level of depressive symptoms compatible with a diagnosis of clinical depression (32).…”

Section: Covariatesmentioning

confidence: 99%

Attendance at Religious Services, Prayer, Religious Coping, and Religious/Spiritual Identity as Predictors of All-Cause Mortality in the Black Women's Health Study

VanderWeele¹,

Yu²,

Cozier³

et al. 2017

American Journal of Epidemiology

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“…For participants with missing CES-D scores in 2005, their score from the 1999 questionnaire was used, if available. The CES-D score is routinely categorized as ‘absence of depressive symptoms’ (score <16), moderate depressive symptoms (score 16–23) and severe depressive symptoms (score ≥24) [ 111 ].…”

Section: Methodsmentioning

confidence: 99%

Stress and Spirituality in Relation to HPA Axis Gene Methylation Among US Black women: Results from the Black Women’s Health Study and the Study on Stress, Spirituality and Health

et al. 2021

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Background: Few epigenetics studies have been conducted within the Black community to examine the impact of diverse psychosocial stressors and resources for resiliency on the stress pathway (hypothalamus–pituitary–adrenal axis). Methods: Among 1000 participants from the Black Women's Health Study, associations between ten psychosocial stressors and DNA methylation (DNAm) of four stress-related genes ( NR3C1, HSDB1, HSD11B2 and FKBP5) were tested. Whether religiosity or spirituality (R/S) significantly modified these stress-DNAm associations was also assessed. Results: Associations were found for several stressors with DNAm of individual CpG loci and average DNAm levels across each gene, but no associations remained significant after false discovery rate (FDR) correction. Several R/S variables appeared to modify the relationship between two stressors and DNAm, but no identified interaction remained significant after FDR correction. Conclusion: There is limited evidence for a strong signal between stress and DNAm of hypothalamus–pituitary–adrenal axis genes in this general population cohort of US Black women.

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“…Mioma uteri adalah sumber morbiditas utama bagi wanita usia subur (Stewart et al, 2013) dan merupakan indikasi utama untuk histerektomi (Wise et al, 2015). Saat ini ada beberapa pilihan untuk mengobati mioma uteri, mulai dari pendekatan yang paling konservatif hingga pendekatan yang paling invasif tergantung kondisi penderita (El Balat et al, 2018).…”

Section: Pembahasanunclassified

Pengaruh Riwayat Kesehatan Reproduksi terhadap Kejadian Mioma Uteri pada Perempuan di Perkotaan Indonesia

Tumaji¹,

Rukmini

Oktarina

et al. 2020

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Uterine myoma is a reproductive health problem that causes serious morbidity and can aﬀect the quality of life of suﬀ erers. Many factors cause uterine myoma. This study aims to analyze the factors related to reproductive health history that can inﬂuence the occurrence of uterine myoma in women in urban Indonesia. This study is a non-intervention analysis which is a further analysis of the 2016 PTM Research results. The 2016 PTM research design is cross-sectional. The population is all women aged 25-64 years in urban Indonesia. Data collection was carried out by interview. In this paper, the data analyzed were respondent characteristics, reproductive health history and the incidence of uterine myomas. Data were analyzed univariate, bivariate, and multivariate. The results showed that the age of menarche and parity did not aﬀ ect the incidence of uterine myoma (p= 0.861 and p= 0.424). Meanwhile, giving birth to a child for the ﬁ rst time under the age of 30 reduced the risk by 48% (95% CI: 0.439-0.607). Having children 1-2 has a risk of 1.3 times greater than those who have more than 2 children (95% CI: 1.126-1.463). Use of contraceptives decreases risk by 30% (95% CI: 0.613-0808). The use of hormonal drugs for infertility treatment increases the risk 3.2 times greater (95% CI: 2.562-4.013). Women who did not use hormone replacement therapy were reduced by around 74% (95% CI: 0.114-0.608). The incidence of uterine myoma is inﬂuenced by the age of ﬁ rst birth, number of children, use of contraceptives, use of hormonal drugs for infertility treatment, and hormone replacement therapy drugs. Health promotion is needed so that risk factors that can be prevented/modiﬁ ed can be minimized to reduce the chance of developing uterine myoma. Abstrak Mioma uteri merupakan masalah kesehatan reproduksi yang menyebabkan morbiditas yang cukup serius serta dapat mempengaruhi kualitas hidup penderitanya. Banyak faktor yang menjadi penyebab mioma uteri. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang terkait riwayat kesehatan reproduksi yang dapat mempengaruhi terjadinya mioma uteri pada perempuan di perkotaan Indonesia. Penelitian ini adalah analisis non-intervensi yang merupakan analisis lanjut dari data hasil riset PTM 2016. Desain riset PTM 2016 adalah potong lintang dengan populasi seluruh perempuan usia 25–64 tahun di perkotaan Indonesia. Pengumpulan data dilakukan dengan wawancara. Dalam tulisan ini, data yang dianalisis adalah karakteristik responden, riwayat kesehatan reproduksi serta kejadian mioma uteri. Data dianalisis secara univariat, bivariat, dan multivariat. Hasil menunjukkan umur menarche dan paritas tidak berpengaruh terhadap kejadian mioma uteri (p= 0,861 dan p= 0,424). Sementara itu, melahirkan anak pertama kali di bawah umur 30 tahun menurunkan risiko sebesar 48% (95%CI: 0,439–0,607). Memiliki anak 1–2 memiliki risiko 1,3 kali lebih besar dibandingkan dengan yang memiliki anak lebih dari 2 (95%CI: 1,126–1,463). Penggunaan alat kontrasepsi menurunkan risiko sebesar 30% (95%CI: 0,613–0,808). Penggunaan obat-obatan hormonal pengobatan infertilitas meningkatkan risiko 3,2 kali lebih besar (95%CI: 2,562–4,013). Perempuan yang tidak menggunakan obat-obatan terapi sulih hormon risikonya berkurang sekitar 74% (95%CI: 0,114–0,608). Kejadian mioma uteri dipengaruhi oleh umur pertama kali melahirkan, jumlah anak, penggunaan alat kontrasepsi, penggunaan obat-obatan hormonal pengobatan infertilitas, dan obat-obatan terapi sulih hormon. Diperlukan promosi kesehatan sehingga faktor risiko yang dapat dicegah/dimodiﬁ kasi dapat diminimalkan untuk mengurangi peluang terkena mioma uteri.

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Depressive symptoms and risk of uterine leiomyomata

Cited by 14 publications

References 63 publications

Attendance at Religious Services, Prayer, Religious Coping, and Religious/Spiritual Identity as Predictors of All-Cause Mortality in the Black Women's Health Study

Attendance at Religious Services, Prayer, Religious Coping, and Religious/Spiritual Identity as Predictors of All-Cause Mortality in the Black Women's Health Study

Stress and Spirituality in Relation to HPA Axis Gene Methylation Among US Black women: Results from the Black Women’s Health Study and the Study on Stress, Spirituality and Health

Pengaruh Riwayat Kesehatan Reproduksi terhadap Kejadian Mioma Uteri pada Perempuan di Perkotaan Indonesia

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