Depressive symptoms and quality of life in people with age‐ related macular degeneration

Mathew, Remy Sheena; Delbaere, Kim; Lord, Stephen R.; Beaumont, Paul; Vaegan,; Madigan, Michele C.

doi:10.1111/j.1475-1313.2011.00848.x

Cited by 70 publications

(81 citation statements)

References 21 publications

(41 reference statements)

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“…[1][2][3][4] The advanced forms of AMD are associated with a debilitating loss of central vision, impacting on ability to perform activities of daily living, 5,6 quality of life, 5,[7][8][9] wellbeing and mood, 5,10,11 social participation, 12 and risk of falls. [13][14][15] A key aim of future interventions must be to prevent the progression to this end stage in people with intermediate AMD.…”

Section: Resultsmentioning

confidence: 99%

Determining Optimal Test Parameters for Assessing Dark Adaptation in People With Intermediate Age-Related Macular Degeneration

Binns

Taylor

Edwards

et al. 2018

Invest. Ophthalmol. Vis. Sci.

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Citation: Binns AM, Taylor DJ, Edwards LA, Crabb DP. Determining optimal test parameters for assessing dark adaptation in people with intermediate age-related macular degeneration. Invest Ophthalmol Vis Sci. 2018;59:AMD114-AMD121. https:// doi.org/10.1167/iovs.18-24211 PURPOSE. The primary aim was to determine optimal test conditions for evaluating dark adaptation in intermediate age-related macular degeneration (iAMD) in order to minimize test time while maintaining diagnostic sensitivity.METHODS. People with AMD and age-similar controls were recruited (aged >55 years). Rod intercept time (RIT) was assessed after a 76%, 70%, and 65% rhodopsin bleach at 58 eccentricity and 76% and 70% bleach at 128. Test order was randomized and a 30-minute washout period added between tests. Results were compared between control and iAMD groups and receiver operating characteristics (ROC) curves were constructed. RESULTS.A total of 26 participants with variable grades of macular health attended for two visits. There was a statistically significant difference in average RIT between the control and iAMD groups at 58 (median, IQR controls ¼ 5.8 minutes, 3.8-7.5; iAMD ¼ 20.6 minutes, 11.1-30.0; Mann-Whitney, P ¼ 0.01) and at 128 (mean, controls: 4.54 minutes 6 2.12 SD, iAMD ¼ 7.72 minutes 6 3.37 SD; independent samples t-test, P ¼ 0.03) following a 76% bleach. Area under the ROC curves was 0.83 (confidence interval [CI]: 0.64-1.0) and 0.79 (CI: 0.59-0.99) for these two test conditions, respectively. Five participants (45%) in the iAMD group had RITs >20 minutes for 76% bleach at 58, but none for any other test condition.CONCLUSIONS. Nearly half of the participants with iAMD produced unacceptably long recovery times (>20 minutes) using a 76% bleach at 58 eccentricity. The 76% bleach at 128 provided almost equivalent separation between AMD and controls but recovery was achieved within 20 minutes.

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Section: Resultsmentioning

confidence: 99%

Determining Optimal Test Parameters for Assessing Dark Adaptation in People With Intermediate Age-Related Macular Degeneration

Binns

Taylor

Edwards

et al. 2018

Invest. Ophthalmol. Vis. Sci.

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“…[8][9][10][11] Previous studies have shown the prevalence rate of depression among patients with AMD to be between 32.5% and 44.4%. 4,12,13 Older adults with both vision impairment and depression face substantially greater difficulty with a variety of functional and social roles when compared with patients with either disorder independently, suggesting that the effect on QOL may be negatively synergistic. 14 Dissatisfaction with the performance of valued activities, including living independently, socializing, reading, and driving, as well as lack of adaptation to reduced vision, has been associated with increased prevalence of depression in patients with AMD.…”

mentioning

confidence: 98%

Prevalence and impact of depressive symptoms in patients with age-related macular degeneration

Jivraj

Tennant

et al. 2013

Canadian Journal of Ophthalmology

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“…Mathew ve ark. 19 tarafından 145 YBMD'li ve kontrol hastalarında yaptıkları çalışmalarında, YBMD'li hastaların %44'de kontrol grubu hastaların ise %18'de depresif semptomlar tespit etmişlerdir. Popescu ve ark.…”

Section: Discussionunclassified

Glokom Hastalığı ve Yaşa Bağlı Makula Dejeneransının Yaşam Kalitesi Üzerine Etkileri

Koçak¹,

Onur²,

Kaya³

et al. 2014

tjo

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Amaç: Glokom hastalığı ve yaşa bağlı makula dejeneransı (YBMD) nedeniyle tedavi gören hastalarda, depresif belirtilerin ve anksiyete belirtilerinin varlığının ve yaşam kalitesinin değerlendirilmesidir. Gereç ve Yöntem: 1 Mart 2008-30 Haziran 2008 tarihleri arasında, kliniğimizde takip ve tedavisi yapılan 60 glokom ve 60 YBMD hastası çalışmaya alındı. Kontrol grubu olarak, gözlük muayenesi için gelen ve ek bir şikayeti olmayan 60 hasta dahil edildi. Glokom ve YBMD hastalarının psikiyatrik belirtiler ve yaşam kalitesi üzerine etkilerini değerlendirmek amacıyla, hastalara hastane anksiyete depresyon ölçeği (Hamilton Anksiyete Derecelendirme Ölçeği-HAD), dünya sağlık örgütü yaşam kalitesi ölçeği kısa formu (WHOQOL-BREF TR) verilerek doldurmaları istendi. Çalışma grubunu oluşturan hastaların ve kontrol grubunun yaş, cinsiyet, eğitim durumu kaydedildi. Bulgular: Glokomlu ve YBMD'li hasta gruplarında HADD (Hamilton Anksiyete Derecelendirme Ölçeği-Depresyon) ve HADA (Hamilton Anksiyete Derecelendirme Ölçeği-Anksiyete) alt puanları kontrol grubundan anlamlı düzeyde yüksek bulundu (p<0,05). Glokomlu ve YBMD'li hasta grubu arasında HADD ve HADA puanları arasında anlamlı fark bulunmadı (p>0,05). Glokomlu ve YBMD'li hasta gruplarında WHOQOL-BREF fiziksel, sosyal, çevresel ve psikolojik alanlardaki yaşam kalitesi puanı kontrol grubundan anlamlı olarak düşük bulundu (p<0,05). Glokomlu ve YBMD'li hasta grubu arasında fiziksel, sosyal, çevresel ve psikolojik alanlardaki yaşam kalitesi puanları arasında anlamlı fark bulunmadı (p>0,05). Sonuç: Glokomlu ve YBMD'li hastaların normal populasyona göre yaşam kalitesinin bozulduğu, bu hastaların depresif belirtilerin ve anksiyete belirtilerinin daha fazla bulunduğu gösterilmiştir. Bu nedenle glokomlu ve YBMD'li hastalar gibi kronik seyirli göz hastaların tedavi ve takipleri sürecinde psikiyatrik semptomlar açısından değerlendirilmesi ve desteklenmesinin, hastaların yaşam kalitesi ve prognozunu olumlu yönde etkileyeceği düşüncesindeyiz. (Turk J Ophthalmol 2014; 44: 83-7) Anahtar Kelimeler: Anksiyete, depresyon, glokom, yaşam kalitesi, YBMD Objectives: The aim of the study was to assess the depressive and anxiety symptoms and the quality of life (QofL) in patients treated for glaucoma and age-related macular degeneration (AMD). Materials and Methods: Between March 1 and June 30, 2008, 60 outpatients with glaucoma and AMD were included into the study. As controls, sixty patients with similar sociodemographic features and who applied to the Ophthalmology Clinics with refractive errors only were taken. All patients and controls were applied the 17-item Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HARS), the World Health Organization Quality of Life Assessment-BREF (WHOQOL-BREF) Turkish version. Results: The mean HDRS and HARS scores of the glaucoma and AMD patients were significantly higher than those of the controls (p<0.05). The mean HDRS and HARS scores did not show a significant difference between the patients with glaucoma and AMD (p>0.05). In the glaucoma and...

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Depressive symptoms and quality of life in people with age‐ related macular degeneration

Cited by 70 publications

References 21 publications

Determining Optimal Test Parameters for Assessing Dark Adaptation in People With Intermediate Age-Related Macular Degeneration

Determining Optimal Test Parameters for Assessing Dark Adaptation in People With Intermediate Age-Related Macular Degeneration

Prevalence and impact of depressive symptoms in patients with age-related macular degeneration

Glokom Hastalığı ve Yaşa Bağlı Makula Dejeneransının Yaşam Kalitesi Üzerine Etkileri

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