Depressive symptomatology in coronary artery bypass graft surgery patients

Pirraglia, Paul A.; Peterson, Janey C.; Williams-Russo, Pamela; Gorkin, Larry; Charlson, Mary E.

doi:10.1002/(sici)1099-1166(199908)14:8<668::aid-gps988>3.0.co;2-9

Cited by 116 publications

(89 citation statements)

References 61 publications

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“…6 Depression, present in 20% to 25% of patients undergoing CABG, 7 is an independent prognostic factor for mortality, readmission, and cardiac events after CABG. 8 -10 Therefore, it is likely that depression also influences functional response after CABG.…”

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confidence: 99%

Patients With Depressive Symptoms Have Lower Health Status Benefits After Coronary Artery Bypass Surgery

et al. 2005

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Background-Depression is an established independent prognostic factor for mortality, readmission, and cardiac events after CABG surgery. However, limited data exist on whether depression influences functional outcomes after CABG. Methods and Results-We followed 963 patients who underwent first CABG between February 1999 and February 2001. At baseline and at 6 months after CABG, we interviewed patients to assess depressive symptoms using the Geriatric Depression Scale (GDS) and physical function using the Short Form-36 Physical Component Scale (PCS). The patient's physical function was considered improved if the PCS score increased Ն5 points at 6 months. Patients with high GDS scores were younger, were more often female, and had worse physical function and higher comorbidity than patients with low GDS scores. Rates of improvement in physical function were 60.1% for a GDS score Ͻ5 (below 75th percentile), 49.8% for a GDS score between 5 and 9 (75th to 90th percentile), and 39.7% for a GDS score Ն10 (Ն90th percentile; Pϭ0.002 for the trend). Depressive symptoms remained a significant independent predictor of lack of functional improvement after adjustment for severity of coronary artery disease, angina class, baseline PCS score, and medical history. A GDS score Ն10 was a stronger inverse risk factor for functional improvement after CABG than such traditional measures of disease severity as previous myocardial infarction, heart failure on admission, history of diabetes, and left ventricular ejection fraction. Conclusions-Higher levels of depressive symptoms at the time of CABG are a strong risk factor for lack of functional benefits 6 months after CABG.

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Section: See P 250mentioning

confidence: 99%

Patients With Depressive Symptoms Have Lower Health Status Benefits After Coronary Artery Bypass Surgery

et al. 2005

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“…These problems occur in up to 15% and 20% of the patients, respectively (Griffiths et al, 2007;Tully, 2012), and may hamper full recovery (Granja et al, 2012;McKhann et al, 1997;Pirraglia et al, 1999).…”

Section: Introductionmentioning

confidence: 99%

Trait anxiety mediates the effect of stress exposure on post-traumatic stress disorder and depression risk in cardiac surgery patients

Kok

Sep

Veldhuijzen

et al. 2016

Journal of Affective Disorders

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a b s t r a c tBackground: Post-traumatic stress disorder (PTSD) and depression are common after cardiac surgery. Lifetime stress exposure and personality traits may influence the development of these psychiatric conditions. Methods: Self-reported rates of PTSD and depression and potential determinants (i.e., trait anxiety and stress exposure) were established 1.5 to 4 years after cardiac surgery. Data was available for 1125 out of 1244 (90.4%) participants. Multivariable linear regressions were conducted to investigate mediating and/ or moderating effects of trait anxiety on the relationship between stress exposure, and PTSD and depression. Pre-planned subgroup analyses were performed for both sexes. Results: PTSD and depression symptoms were present in 10.2% and 13.1% of the participants, respectively. Trait anxiety was a full mediator of the association between stress exposure and depression in both the total cohort and female and male subgroups. Moreover, trait anxiety partially mediated the relationship between stress exposure and PTSD in the full cohort and the male subgroup, whereas trait anxiety fully mediated this relationship in female patients. Trait anxiety did not play a moderating role in the total patient sample, nor after stratification on gender. Limitations: The unequal distribution of male (78%) and female patients (22%) might limit the generalizability of our findings. Furthermore, risk factors were investigated retrospectively and with variable follow-up time. Conclusions: In cardiac surgery patients, trait anxiety was found to be an important mediator of postoperative PTSD and depression. Prospective research is necessary to verify whether these factors are reliable screening measures of individuals' vulnerability for psychopathology development after cardiac surgery.

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“…En un estudio de segui miento postquirúrgico tras el diagnóstico de IAM, Pirraglia et al, identificaron al apoyo social deficiente, entre otros, como un factor predictivo de depresión 29 . En suma, el presente trabajo demuestra una alta prevalencia de síntomas depresivos en pa cientes ingresados a una unidad coronaria con diagnóstico de IAM.…”

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Prevalencia y evolución de síntomas depresivos en pacientes hospitalizados por infarto agudo al miocardio y su relación con procedimientos de revascularización

et al. 2010

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follow-up (p < 0.01). At baseline BDI score was 10.2 ± 5.1 and 9.1 ± 4.4 among patients subjected or not subjected to IRT, respectively (NS). The figures at 3 months of follow up were 9. 9 ± 5.6 and 4.1 ± 2.5, respectively (p < 0,01). At baseline and three months BDI, anxiety and perceived social support were significantly correlated. Conclusions: Depressive symptoms were frequent after MI in this group of patients, and decreased at follow up only among patients not subjected to IRT. (Rev Med Chile 2010; 138: 701-706).

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Depressive symptomatology in coronary artery bypass graft surgery patients

Cited by 116 publications

References 61 publications

Patients With Depressive Symptoms Have Lower Health Status Benefits After Coronary Artery Bypass Surgery

Patients With Depressive Symptoms Have Lower Health Status Benefits After Coronary Artery Bypass Surgery

Trait anxiety mediates the effect of stress exposure on post-traumatic stress disorder and depression risk in cardiac surgery patients

Prevalencia y evolución de síntomas depresivos en pacientes hospitalizados por infarto agudo al miocardio y su relación con procedimientos de revascularización

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