Depressive symptom patterns and their consequences for diagnosis of affective disorders in cancer patients

Reuter, Katrin; Raugust, S; Bengel, Jiirgen; Härter, Martin

doi:10.1007/s00520-004-0694-2

Cited by 27 publications

(28 citation statements)

References 47 publications

(64 reference statements)

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“…This indicated that fatigue appears in conjunction with depression. These results are consistent with previous studies [43][44][45]. Sawada et al [46] found that many patients experienced fatigue and depression and their levels increased after beginning of the treatment.…”

Section: Discussionsupporting

confidence: 83%

An Original Research about: The Associations of Depression and Fatigue with Quality of Life among Palestinian Patients with Cancer

Dreidi¹,

Asmar²,

Al-Rjoub³

2017

Health Sci J

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Purpose: To explore the relationships between depression, fatigue and QoL among patients diagnosed with cancer in the West Bank.Method: This was a descriptive, correlational study. 172 patients with lung, breast, colon, prostate and stomach cancer participated in the study. Depression, fatigue and quality of life were assessed for patients who undergoing chemotherapy. All instruments were reliable and valid. Results:The mean score for depression was 22 (SD=8). This indicated that many patients in this study experienced depression. The participants had moderate fatigue 51 (SD=39). The same results were found in quality of life dimensions, as the mean score for functional scales and global health status ranged from 50 to 73 and for symptom scales ranged from 27 to 45. Regarding the correlation, the results showed that there were significant correlation between depression and fatigue and all quality of life dimensions (all p<0.05). Conclusion:Depression and fatigue were significantly correlated with QoL. The impact of depression should be taken into consideration by health care workers when designing or planning interventions to improve QoL for patients with cancer through accurate and early assessment. The moderate fatigue that patients with cancer experienced by the disease or by the treatment should also be taken into account. Each one of the key variables negatively affects QoL in separate. The occurrence of them simultaneously may increase the worse effect on QoL for patients with cancer. Based on that, depression and fatigue should be assessed for each patient with cancer.

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Section: Discussionsupporting

confidence: 83%

An Original Research about: The Associations of Depression and Fatigue with Quality of Life among Palestinian Patients with Cancer

Dreidi¹,

Asmar²,

Al-Rjoub³

2017

Health Sci J

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“…Results show that the loss of interest question is somewhat better than the depression question when used alone. This corresponds to research showing that, of many symptoms of depression, loss of interest best discriminated between patients with and without diagnosis of comorbid affective disorder (Reuter et al, 2004). However, two questions are significantly better than any one question for detecting depression (Youden score was 0.78 for two questions, 0.54 for the depression question and 0.69 for the interest question).…”

Section: Discussionmentioning

confidence: 99%

Are one or two simple questions sufficient to detect depression in cancer and palliative care? A Bayesian meta-analysis

Mitchell

2008

Br J Cancer

106

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The purpose of this study is to examine the value of one or two simple verbal questions in the detection of depression in cancer settings. This study is a systematic literature search of abstract and full text databases to January 2008. Key authors were contacted for unpublished studies. Seventeen analyses were found. Of these, 13 were conducted in late stage palliative settings. (1) Single depression question: across nine studies, the prevalence of depression was 16%. A single 'depression' question enabled the detection of depression in 160 out of 223 true cases, a sensitivity of 72%, and correctly reassured 964 out of 1166 non-depressed cancer sufferers, a specificity of 83%. The positive predictive value (PPV) was 44% and the negative predictive value (NPV) 94%. (2) Single interest question: there were only three studies examining the 'loss-of-interest' question, with a combined prevalence of 14%. This question allowed the detection of 60 out of 72 cases (sensitivity 83%) and excluded 394 from 459 non-depressed cases (specificity of 86%). The PPV was 48% and the NPV 97%. (3) Two questions (low mood and low interest): five studies examined two questions with a combined prevalence of 17%. The two-question combination facilitated a diagnosis of depression in 138 of 151 true cases (sensitivity 91%) and gave correct reassurance to 645 of 749 non-cases (specificity 86%). The PPV was 57% and the NPV 98%. Simple verbal methods perform well at excluding depression in the non-depressed but perform poorly at confirming depression. The 'two question' method is significantly more accurate than either single question but clinicians should not rely on these simple questions alone and should be prepared to assess the patient more thoroughly.

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“…Angesichts der uneinheitlichen Befundlage kann es kaum überraschen, dass auch hier die der Komorbidität zugrunde liegenden psychologischen und neurobiologischen Mechanismen noch weitgehend ungeklärt sind; es erscheint allerdings sehr wahrscheinlich, dass eine erhöhte Komorbidität primär auf die assoziierte Schmerzsymptomatik und Demoralisierung der Patienten zurückzuführen ist bzw. direkte oder indirekte Folge einer pharmakologischen Krebstherapie sein könnte [23].…”

Section: Krebserkrankungenunclassified

Depression als komorbide Störung in der primärärztlichen Versorgung

Pieper

Schulz

Klotsche

et al. 2008

Bundesgesundheitsbl.

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(1) 7.5 % of all primary care patients met criteria for ICD-10 depressive disorders. (2) Depression risk was increased whenever any somatic disorder was present and increased in a dose-response relationship by number of comorbid conditions. (3) Elevation of depression risk was fairly independent of type of diagnosis, although associations with coronary heart disease (OR: 1.7), diabetic complications (OR: 1.7- 2.0), stroke (OR: 2.5) and pain-related chronic disorders (OR: 1.5) were particularly pronounced. Moderate associations were found for hyperlipidaemia (OR: 1.1). (4) Associated with the increasing number of comorbid conditions, patients with comorbid depression had increasingly more disability days and lower health related quality of life. It is concluded that the degree to which the frequency and the deleterious effects of comorbid depression is underestimated and unrecognized is alarming. The use of comorbidity indices might improve recognition.

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Depressive symptom patterns and their consequences for diagnosis of affective disorders in cancer patients

Abstract: Cognitive symptoms should receive special attention in diagnostic procedures for affective disorders in cancer patients. In spite of possible symptom overlap with the cancer disease and its treatment, fatigue proves to be a useful criteria for diagnosis of depression.

Cited by 27 publications

References 47 publications

An Original Research about: The Associations of Depression and Fatigue with Quality of Life among Palestinian Patients with Cancer

An Original Research about: The Associations of Depression and Fatigue with Quality of Life among Palestinian Patients with Cancer

Are one or two simple questions sufficient to detect depression in cancer and palliative care? A Bayesian meta-analysis

Depression als komorbide Störung in der primärärztlichen Versorgung

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