Depressive behavior induced by unpredictable chronic mild stress increases dentin hypersensitivity in rats

Electroacupuncture Reduces Cold Stress-Induced Pain through Microglial Inactivation and Transient Receptor Potential V1 in Mice

“…Furthermore, spared nerve injury increased IL-1β expression in the plasma, spinal dorsal horn, hippocampus, prefrontal cortex, and amygdala [35]. Remarkably, neuropathic pain-inducing nerve injury increased IL-6 expression [32,33]. Injection of IL-6 antibody reliably attenuated peripheral nerve injuryinduced mechanical hyperalgesia [36].…”

“…In ammatory mediators such as IL-1β, IL-6, and TNF-α are mainly produced by non-neuronal cells such as astrocytes and microglia. Chronic unpredictable mild stress can induce depression in mice and increase serum cytokines such as IL-1β, IL6, and TNFα [32,33]. Recently, researchers suggested that peripheral nerve injury, CNS trauma, and nociceptive DRG neurons increased IL-1β expression [34].…”

Electroacupuncture reduces cold stress-induced pain through microglial inactivation and transient receptor potential V1 in mice

“…Inflammatory mediators such as IL-1β, IL-6, and TNF-α are mainly produced by non-neuronal cells such as astrocytes and microglia. Chronic unpredictable mild stress can induce depression in mice and increase serum cytokines such as IL-1β, IL6, and TNFα [ 31 , 32 ]. Recently, researchers suggested that peripheral nerve injury, CNS trauma, and nociceptive DRG neurons increased IL-1β expression [ 33 ].…”

Clinical evaluation of therapeutic efficacy of selected chemical preparations in the treatment of dentine hypersensitivity in patients utilizing fixed dental prostheses

“…zmiany nastroju, stres, depresja czy współwystępowanie chorób ogólnoustrojowych. [20][21][22] Do oceny skuteczności leczenia przeciwbólowego w medycynie często jest wykorzystywna skala wizualno-analogowa VAS, gdyż pozwala na porównanie wyników z kilku systematycznie powtarzanych pomiarów, wykonanych w określonym przedziale czasowym przez tego samego pacjenta oraz dokonanie porównania wyników pomiędzy różnymi metodami. 23 Podczas zabiegu szlifowania zębów dochodzi do mechanicznego urazu tkanek twardych zęba i utraty szkliwa i/ lub zębiny na dużym obszarze.…”

“…mood changes, stress, depression or coexistence of systemic diseases. [20][21][22] To evaluate the effectiveness of analgesic treatment in medicine, the visualanalogue scale (VAS) is often used, because it allows comparing the results of several systematically repeated measurements taken in a specific time period by the same patient, as well as comparing the results between different methods. 23 During the tooth grinding procedure, mechanical damage to the tooth hard tissues and loss of enamel and/or dentine occurs over a large area.…”