Depressive and Anxiety Disorders in Women With HIV Infection

Morrison, Mary F.; Petitto, John M.; Have, Thomas Ten; Gettes, David R.; Chiappini, Margaret S.; Weber, Anita L.; Brinker-Spence, Priscilla; Bauer, Russell M.; Douglas, Steven D.; Evans, Dwight L.

doi:10.1176/appi.ajp.159.5.789

Cited by 322 publications

(253 citation statements)

References 62 publications

(52 reference statements)

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“…Lifetime generalized anxiety disorder rates were comparable in HIV-infected men and male controls, and to reports in the general population (1-2%) (Robins et al, 1991;Kessler et al, 1994) and in HIV cross-sectional studies (Williams et al, 1991;Dew et al, 1997), but are lower than in women (Morrison et al, 2002). Prior history of psychiatric disorder was the most potent predictor of a major depressive episode.…”

Section: Discussionsupporting

confidence: 66%

Two-year prospective study of major depressive disorder in HIV-infected men

Atkinson

Heaton

Patterson

et al. 2008

Journal of Affective Disorders

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Objective-The risks and factors contributing to major depressive episodes in HIV infection remain unclear. This 2-year prospective study compared cumulative rates and predictors of a major depressive episode in HIV-infected (HIV+) men (N=297) and uninfected (HIV−) risk-group controls (N=90).Method-By design participants at entry were without current major depression, substance dependence or major anxiety disorder. Standardized neuromedical, neuropsychological, neuroimaging, life events, and psychiatric assessments (Structured Clinical Interview for DSM III-R) were conducted semi-annually for those with AIDS, and annually for all others.

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Section: Discussionsupporting

confidence: 66%

Two-year prospective study of major depressive disorder in HIV-infected men

Atkinson

Heaton

Patterson

et al. 2008

Journal of Affective Disorders

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“…[28][29][30][31][32][34][35][36][51][52][53][54][55][56][57][58][59][60][61] Significantly higher percentages of women who were HIV-positive, had experienced IPV in the past year, and had used hard drugs in the past 30 days exhibited higher depressive symptoms, without adjusting for sociodemographic factors. However, when adjusting for the other SAVA factors, sociodemographic factors, social support and alcohol abuse, only the experience of IPV in the past year and drug use in the past 30 days remained significant, as did reporting low social support.…”

Section: Discussionmentioning

confidence: 99%

“…[24][25][26] Women who experience violence in their intimate relationships are at much higher risk of experiencing depressive symptoms. [27][28][29][30][31][32][33] Living with HIV has also been associated with increased depression; studies show that HIV-positive women experience higher rates of depressive symptoms compared to their sociodemographically comparable HIV-negative counterparts. 9,32 Finally, associations between depressive symptoms and substance use have been documented; the rate of depression among women abusing illegal substances was found to be significantly higher than that of nonsubstance abusing women and the general population.…”

Section: Introductionmentioning

confidence: 99%

“…[27][28][29][30][31][32][33] Living with HIV has also been associated with increased depression; studies show that HIV-positive women experience higher rates of depressive symptoms compared to their sociodemographically comparable HIV-negative counterparts. 9,32 Finally, associations between depressive symptoms and substance use have been documented; the rate of depression among women abusing illegal substances was found to be significantly higher than that of nonsubstance abusing women and the general population. 34,35 While individual associations are well-documented in the literature, and some studies show that being HIV-positive and experiencing IPV simultaneously increases the odds of depression, 36,37 no study has evaluated the combined effect of IPV, HIV, and substance use on depressive symptoms among urban women.…”

Section: Introductionmentioning

confidence: 99%

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The Syndemic Effects of Intimate Partner Violence, HIV/AIDS, and Substance Abuse on Depression among Low-Income Urban Women

et al. 2013

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Intimate partner violence (IPV), HIV/AIDS, and substance use are epidemics among low-income urban women that have been described together as the "SAVA syndemic" because of their co-occurring nature. This study examines the synergistic or "syndemic" effect of these three health issues on depression among urban women and evaluates social support as a protective factor that might reduce depressive symptoms associated with the Substance Abuse, Violence, and AIDS (SAVA) syndemic. Data from 445 urban women were collected through in-person interviews. All women were over the age of 18, not pregnant, English speaking, and reported having a main partner in the past year. Twenty-five percent had experienced all three factors of the SAVA syndemic (were HIV-positive, had experienced IPV in the past year, and had used cocaine or heroin in their lifetime). HIV-positive status, hard drug use, IPV, and low levels of social support were all individually associated with greater depressive symptoms. When controlling for demographics and other SAVA factors, IPV and hard drug use in the past 30 days remained associated with depressive symptoms, as did low social support. However, social support did not modify the effect of the SAVA factors on depression. Compared to women who experienced no SAVA factors, women who had experienced all three factors were 6.77 times more likely to have depressive symptoms. These findings confirm that IPV is significantly associated with depressive symptoms and that the syndemic impact of IPV, substance use, and HIV could have even more extreme effects on depression outcomes.

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“…Quanto aos nove trabalhos sobre a prevalência de depressão em mulheres HIV-positivas (James, 1988;Brown e Rundell, 1990;Pergami et al, 1993;Lovisi e Morgado, 1996;Goggin et al, 1998;Ickovics et al, 2001;Morrison et al, 2002;Evans et al, 2002;Tostes et al, 2004), apenas três são controlados (Pergami et al, 1993;Morrison et al, 2002;Evans et al, 2002) (Tabela 3). Desses, somente um mostrou prevalência de depressão significativamente maior nas mulheres infectadas pelo HIV comparadas às soronegativas .…”

Section: Prevalência De Depressão Em Indivíduos Infectados Pelo Hivunclassified

Infecções virais e depressão

Stumpf¹,

Rocha

Proietti

2006

J. bras. psiquiatr.

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ResumoObjetivo: A associação entre depressão e viroses é estudada há quase dois séculos, com resultados conflitantes. O objetivo deste trabalho é fazer uma análise crítica dos estudos existentes na literatura sobre essa relação. Métodos: A pesquisa bibliográfica utilizou as fontes eletrônicas de busca MEDLINE e LILACS (1966 a agosto 2005). As referências dos artigos foram utilizadas como fonte adicional de consulta. Resultados: Foram abordados os trabalhos que trataram da associação entre depressão e os vírus HIV, HCV, EBV, influenza, HSV, HBV, HAV, BDV e HTLV. A relação entre HIV e depressão mostrou-se bem documentada na literatura. Existem indícios de que a prevalência desse transtorno nos indivíduos infectados pelo HIV seja maior que a encontrada nos soronegativos. Além disso, estudos constataram que a depressão está associada a pior prognóstico da infecção. Quanto à associação entre HCV e depressão, os trabalhos sugeriram maior prevalência desse transtorno psiquiátrico nos portadores do HCV comparados à população geral. Não existem evidências científicas suficientes para dar suporte à relação entre os demais vírus e depressão. Conclusão: As associações mais bem fundamentadas foram aquelas entre depressão e os vírus HIV e HCV. A relação entre as demais viroses e depressão precisa ser mais bem estudada, e trabalhos com delineamento adequado se fazem necessários. Palavras-chave: depressão, viroses, HIV, HCV, HTLV. AbstractObjective: The association between depression and viruses has been evaluated for almost two centuries now, with conflicting results. The objective of the present study is to perform a critical review of published studies in the literature about this relationship. Methods: Databases MEDLINE and LILACS were searched between 1966 and 2005 (until August). The references of the articles were used as additional source of data. Results: Studies about the link between depression and infection with viruses HIV, HCV, EBV, influenza, HSV, HBV, HAV, BDV and HTLV were analyzed. The association between HIV and depression was well documented in literature. There are evidences that the prevalence of this disorder in HIV-infected individuals is greater than that found in seronegatives. Moreover, studies concluded that depression is associated with a worse course of infection. Regarding the link between HCV and depression, studies suggested a greater prevalence of this psychiatric disorder in HCV-infected people compared with general population. There is not enough scientific evidence to support the association between other viruses and depression. Conclusion: The best-studied relationships were those between depression and viruses HIV and HCV. Regarding the association of other viruses with depression, more research is needed.

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Depressive and Anxiety Disorders in Women With HIV Infection

Cited by 322 publications

References 62 publications

Two-year prospective study of major depressive disorder in HIV-infected men

Two-year prospective study of major depressive disorder in HIV-infected men

The Syndemic Effects of Intimate Partner Violence, HIV/AIDS, and Substance Abuse on Depression among Low-Income Urban Women

Infecções virais e depressão

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