Case historyA 27-year-old Caucasian woman presented to the accident and emergency department in September 2014 with a 24-h history of left hip pain, difficult walking, and altered sensation in her leg. She was referred to the trauma and orthopedic teams. Pain was present in the groin and buttock, radiating down to the knee. There was no history of trauma. She had a past medical history of depression for which she took pregabalin and quetiapine, which was started 6 weeks before. She had no known drug allergies and lived alone.On examination, she was afebrile and hemodynamically stable. There was maximal tenderness over her left ischial tuberosity, with minor tenderness in the buttock but not in the groin. Passive hip movements were pain free. The abdomen was soft and non-tender. There was a graze on the extensor surface of her left elbow, with associated minor erythema but no tracking cel-69 ABSTRACT Introduction: Lumbosacral plexopathies are rare in patients who present to both primary care and the accident and emergency departments. Presenting symptoms are often non-specific, such as lower back pain, sciatica, or pelvic pain, making diagnosis difficult. Furthermore, there are numerous and diverse causes of lumbosacral plexopathy. Case Report: We present a case of a previously well 27-year-old female who presented to the accident and emergency department with hip pain, difficult walking, and altered sensation in her leg. She was referred to the orthopedic team, where magnetic resonance imaging (MRI) suggested that necrotizing fasciitis was a possible diagnosis because of abundant edema and muscle swelling and thus subsequently underwent surgical exploration. Following subsequent investigation, her symptoms and MRI features were determined to be a result of lumbosacral plexopathy secondary to immobility with rhabdomyolysis. Conclusion: This case highlights the importance of a robust initial clinical history accompanied with appropriate investigations to elicit an accurate diagnosis and also discusses lumbosacral plexopathies in general.