Depression Is Associated with a Higher Risk of Death among Stroke Survivors

Razmara, Ali; Valle, Natalie; Markovic, Daniela; Sanossian, Nerses; Ovbiagele, Bruce; Dutta, Tara; Towfighi, Amytis

doi:10.1016/j.jstrokecerebrovasdis.2017.07.006

Cited by 33 publications

(17 citation statements)

References 38 publications

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“…이상에서 살펴본 봐와 같이 우울증과 심뇌혈관질환은 상관 관계가 있으며 [5], 우울증은 심뇌혈관질환에서 재발과 사망률 을 높일 뿐 아니라 삶의 질을 감소시킨다 [5,7,10]. 심뇌혈관질 환과 우울증의 관련성에 대한 선행연구들이 대부분 유럽, 미국 등의 국외에서 이루어졌으나 [4,5,11,13,14,17,18] Missing value on diagnosis from doctor in depression, stroke, and ischemic heart disease, PHQ-9, and socio-demographic, health and diseases related factors (n=2,155)…”

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Association between Cardio-Cerebro Vascular Disease and Depression and Factors Influencing Depression: The Korean National Health and Nutrition Examination Survey in 2014, 2016

Kim¹,

Song²

2020

J Korean Acad Fundam Nurs

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Purpose: In this study investigated the association between cardio-cerebro vascular disease and depression was examined and factors influencing depression in adults with cardio-cerebro vascular disease were identified. The Korean National Health and Nutrition Examination Survey (KNHANES) data (2014, 2016), which is representative of the Korean population was used.Methods: Data on 9,651 people (male 4,148, female 5,503; age≥19 years old from the KNHANES (Ⅵ-2, Ⅷ-1) were analyzed using frequency, percentage, <i>x</i><sup>2</sup> test, and logistic regression analysis. Depression is defined as major depression with doctor diagnosis or Patient Health Questionnaire-9 score ≥10. Ischemic heart disease (IHD)(myocardial infarction or angina) and stroke were defined as a doctor diagnosis.Results: The prevalence of depression was 20.4% in the IHD group and 22.9% in stroke group, which were statistically significant. After adjusting by sociodemographic, health-related, and independent variables in a logistic regression analysis, IHD (OR=1.91, 95% CI 1.36~2.69) and stroke (OR=1.83, 95% CI 1.23~2.72) were associated with depression. In addition, IHD was significantly associated with depression in women, people divorced or separated, current smokers, people with perceived stress, and hypercholesterolemia. In addition, stroke was significantly associated with depression in women, under the age of 65, with perceived stress.Conclusion: The results of this study show that cardio-cerebro vascular disease is associated with the depression and influencing factors on depression were socio-demographic and health-related characteristics. Therefore, intensive management of depression risk factors and development and application of a program reducing depression for patients with cardio-cerebro vascular disease should be developed.

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Association between Cardio-Cerebro Vascular Disease and Depression and Factors Influencing Depression: The Korean National Health and Nutrition Examination Survey in 2014, 2016

Kim¹,

Song²

2020

J Korean Acad Fundam Nurs

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“…Investigating outcomes that extend beyond motor function is imperative, as an increasing body of literature has shown that survivors of stroke experience feelings of social isolation, difficulty re-integrating into the community, 4 and post-stroke depression (PSD). 5 Post-stroke depression is associated with increased disability, lower HRQOL, and higher mortality, [6][7][8] and approximately 1 in 3 survivors of stroke exhibit symptoms of PSD. 6,9,10 A challenge to reducing depression and improving HRQOL after stroke is the persistent upper extremity (UE) paresis experienced by >60% of survivors of stroke, 11 which leads to greater dependency in mobility and activities of daily living (ADLs).…”

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confidence: 99%

Combined Aerobic Exercise and Task Practice Improve Health-Related Quality of Life Poststroke: A Preliminary Analysis

Rosenfeldt

Linder

Davidson

et al. 2019

Archives of Physical Medicine and Rehabilitation

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Objective: The aim of this project was to determine the effects of lower extremity aerobic exercise coupled with upper extremity repetitive task practice (RTP) on health related quality of life (HRQOL) and depressive symptomology in individuals with chronic stroke. Design: Secondary analysis of data from two randomized controlled trials. Setting: Research laboratory. Participants: Individuals (N=40) with chronic stroke. Interventions: Participants received one of the following interventions: forced exercise + RTP (FE+RTP, n=16), voluntary exercise + RTP (VE+RTP, n=16), or stroke education + RTP (EDU +RTP, n=8). All groups completed 24 sessions, each session lasting 90 minutes. Main Outcome Measure: The Center for Epidemiological Studies-Depression Scale (CES-D) and Stroke Impact Scale (SIS) were used to assess depressive symptomology and HRQOL. Results: There were no significant group-by-time interactions for any of the SIS domains or composite scores. Examining the individual groups following the intervention, those in the FE +RTP and VE+RTP groups demonstrated significant improvements in the following SIS domains: strength, mobility, hand function, activities of daily living, and the physical composite. Additionally, the FE+RTP group demonstrated significant improvements in memory, cognitive

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“…27 Depression after stroke may be associated with increased risk of, and shorter interval to, recurrent stroke, 28,29 though a recent systematic review and meta-analysis found the data on this point to be inconclusive. 30 Of greatest concern is an association between PSD and increased mortality, with several large cohort studies 31,32 and meta-analyses 30,33-35 demonstrating a significantly higher risk of death in depressed stroke survivors (1.4-1.5 times greater in most meta-analyses) as compared with nondepressed stroke patients, consistent with the broader literature linking depression with increased cardiovascular mortality. 36 The nature of the association between depression and poorer outcomes remains unclear.…”

Section: Discussionmentioning

confidence: 67%

Neuropsychiatric Complications after Stroke

Nemani

Gurin

2021

Semin Neurol

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Neuropsychiatric disturbances represent a common and uniquely challenging consequence of stroke. These disorders arise at the intersection of lesion-related brain dysfunction and psychological distress related to the event and its aftermath, making it difficult to identify what symptom is a direct physiological consequence of the stroke. Depression, anxiety, fatigue, apathy, emotionalism, and anger are the most common of these syndromes, and posttraumatic stress disorder related to the stroke event has become increasingly recognized as a relevant entity. Mania, obsessive–compulsive disorder, and psychosis are less commonly encountered but potentially highly debilitating conditions that may be underrecognized. Early identification and treatment may mitigate functional impairment and improve quality of life. Evidence-based guidelines from the general population are often relied upon to guide treatment. Further research is needed to understand and tailor treatment of these disorders in the poststroke population.

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Depression Is Associated with a Higher Risk of Death among Stroke Survivors

Cited by 33 publications

References 38 publications

Association between Cardio-Cerebro Vascular Disease and Depression and Factors Influencing Depression: The Korean National Health and Nutrition Examination Survey in 2014, 2016

Association between Cardio-Cerebro Vascular Disease and Depression and Factors Influencing Depression: The Korean National Health and Nutrition Examination Survey in 2014, 2016

Combined Aerobic Exercise and Task Practice Improve Health-Related Quality of Life Poststroke: A Preliminary Analysis

Neuropsychiatric Complications after Stroke

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