Depression in patients with pulmonary tuberculosis in a tertiary care general hospital

Balaji, Arjun Lakshmana; Ashok, Abhishekh Hulegar; Kumar, Nitish; Mehta, Ravindra

doi:10.1016/j.ajp.2012.12.017

Cited by 18 publications

(17 citation statements)

References 4 publications

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“…1 High prevalence of depression among TB patients has also been reported in various studies from different countries, with great variations between studies. Such high prevalence was reported in Nigeria (27.7%), 2 India (39.5%), 3 Ethiopia (43.4%), 4 Pakistan (46.3%), 5 and Cameroon (61.1%). 6 Findings of research indicate that patients with TB often experience depression because of the chronic nature of the TB infection or its related psychosocioeconomic stressors.…”

Section: Introductionmentioning

confidence: 82%

“…10 Previous studies showed that the prevalence of depression among TB patients was relatively high. [2][3][4][5][6] Depression is a condition that adversely affects patients' ability to cope with stress, the side effects of treatment, and everyday life. Many studies also found that depression had negative effect on treatment adherence, a very important aspect in TB control.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of Depressive Symptoms and Related Risk Factors among Patients with Tuberculosis in China: A Multistage Cross-Sectional Study

Gong

Yan

Qiu

et al. 2018

The American Journal of Tropical Medicine and Hygiene

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Poor mental health among tuberculosis (TB) patients affects not only their compliance with treatments but also their daily lives. Few studies in China have evaluated depressive symptoms among TB patients. The present study aimed to determine the prevalence of depressive symptoms and its associated risk factors among Chinese TB patients. A total of 1,342 TB patients were recruited using a multistage sampling method and interviewed using a structured questionnaire. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Multinomial logistic regression analysis was performed to identify risk factors of depressive symptoms. Of the 1,342 participants included in this study, 48.0% had depressive symptoms. Of these, 34.8% and 13.2% had mild and moderate-to-severe depressive symptoms, respectively. Factors associated with depressive symptoms included family dysfunction, TB-related stigma, poor doctor-patient communication, and lack of knowledge about TB. Depressive symptoms are common among TB patients in China. Efforts of government and stakeholders in the development of relevant policy documents to prevent stigma and create social support for TB patients are necessary. This would not only promote their mental health but also improve their compliance with treatments.

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Section: Introductionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Prevalence of Depressive Symptoms and Related Risk Factors among Patients with Tuberculosis in China: A Multistage Cross-Sectional Study

Gong

Yan

Qiu

et al. 2018

The American Journal of Tropical Medicine and Hygiene

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“…Various explanations for the link have been suggested in the literature, including the effects of stress on immune functioning and the progression from infection to disease [12], [13], the occurrence of neuropsychiatric disorders as adverse events of TB treatment [21], and the diagnosis of TB increases risk of mental illness from the stigma and social isolation that are associated with TB [2], [10], [22].…”

Section: Discussionmentioning

confidence: 99%

“…An association has been described between TB and CMDs, where approximately 39%–70% of pulmonary TB cases have been found to have anxiety or depression [8]–[10]. A link between CMDs and tuberculosis is plausible, and if such a link exists, there are implications for the control and treatment of both diseases [2].…”

Section: Introductionmentioning

confidence: 99%

Common Mental Disorders Associated with Tuberculosis: A Matched Case-Control Study

et al. 2014

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IntroductionDespite the availability of treatment and a vaccine, tuberculosis continues to be a public health problem worldwide. Mental disorders might contribute to the burden of the disease.ObjectiveThe objective of this study was to investigate the association between common mental disorders and tuberculosis.MethodsA matched case-control study was conducted. The study population included symptomatic respiratory patients who attended three referral hospitals and six community clinics in the city of Salvador, Brazil. A doctor’s diagnosis defined potential cases and controls. Cases were newly diagnosed tuberculosis cases, and controls were symptomatic respiratory patients for whom tuberculosis was excluded as a diagnosis by the attending physician. Cases and controls were ascertained in the same clinic. Data collection occurred between August 2008 and April 2010. The study instruments included a structured interview, a self-reporting questionnaire for the identification of common mental disorders, and a questionnaire for alcoholism. An univariate analysis included descriptive procedures (with chi-square statistics), and a multivariate analysis used conditional logistic regression.ResultsThe mean age of the cases was 38 years, and 61% of the cases were males. After adjusting for potential confounders, the odds of tuberculosis were significantly higher in patients dignosed with a common mental disorder (OR: 1.34; 95% CI 1.05–1.70).ConclusionThere appears to be a positive and independent association between common mental disorders and tuberculosis; further epidemiological studies are required to increase our understanding of the possible biological and social mechanisms responsible for this association. Independent of the direction of the association, this finding has implications for the provision of care for mental disorders and for tuberculosis.

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“…It has been reported that the prevalence of depression in pulmonary tuberculosis patients was 13.5% to 72% [13,14]. This difference was due to the different of measurements that used, but most of the research showed that nearly half of pulmonary TB patients were depressed [15]. A survey of 100 patients with pulmonary tuberculosis in South Africa showed that 68% had symptoms of depression, of which 22 were mildly depressed, 38 had moderate depression, and 8 had high depression [11].…”

Section: Introductionmentioning

confidence: 99%

Effect of Duration Tuberculosis Treatment on Depression Symptoms Level of Tuberculosis Patients in Karang Bahagia Primary Health Care Bekasi

Akaputra¹,

Qurrotaa'yun²

2017

Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)

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Tuberculosis (TB) is an inflammatory pulmonary parenchymal disease caused by a bacterial infection of Mycobacterium tuberculosis, which requires a long period of treatment so that it can affect the onset of depression in patients with pulmonary TB. To find out whether there is a correlation between duration of pulmonary TB treatment to depressive symptoms level in patients with pulmonary tuberculosis aged 18 to 65 years at Karang Bahagia Primary Health Care. This research is analytic observational with cross sectional approach. Sampling as many as 55 respondents with data collected in December 2016. The sampling technique using non-probability sampling technique with consecutive sampling. Data were taken from the medical record to determine the duration of treatment and used the PHQ-9 questionnaire to determine the level depression. Data were analyzed using Chi Square. Chi square test showed that there was a significant correlation between duration of lung TB treatment with depressive symptom level with PValue = 0.003. There is a significant correlation between duration of tuberculosis (TB) treatment with depressive symptoms in pulmonary tuberculosis patients aged 18 to 65 years at Karang Bahagia Primary Health Care of Bekasi.

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Depression in patients with pulmonary tuberculosis in a tertiary care general hospital

Cited by 18 publications

References 4 publications

Prevalence of Depressive Symptoms and Related Risk Factors among Patients with Tuberculosis in China: A Multistage Cross-Sectional Study

Prevalence of Depressive Symptoms and Related Risk Factors among Patients with Tuberculosis in China: A Multistage Cross-Sectional Study

Common Mental Disorders Associated with Tuberculosis: A Matched Case-Control Study

Effect of Duration Tuberculosis Treatment on Depression Symptoms Level of Tuberculosis Patients in Karang Bahagia Primary Health Care Bekasi

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